Mfsd2a (MFSD2 lysolipid transporter A, lysophospholipid)

Gene: Mfsd2a (MFSD2 lysolipid transporter A, lysophospholipid) Rattus norvegicus

Analyze

Symbol:

Mfsd2a

Name:

MFSD2 lysolipid transporter A, lysophospholipid

RGD ID:

1310174

Description:

Predicted to enable lysophosphatidylcholine flippase activity; lysophospholipid:sodium symporter activity; and oleate transmembrane transporter activity. Predicted to be involved in central nervous system development; lipid transport; and transcytosis. Predicted to act upstream of or within several processes, including photoreceptor cell development; regulation of lipid metabolic process; and retina development in camera-type eye. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 15. Orthologous to human MFSD2A (MFSD2 lysolipid transporter A, lysophospholipid); INTERACTS WITH 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical LOC298504; LOC298504; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; Mfsd2; RGD1310174; sodium-dependent lysophosphatidylcholine symporter 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	140,510,933 - 140,525,828 (-)	NCBI		GRCr8
mRatBN7.2	5	135,225,801 - 135,240,744 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	135,225,816 - 135,240,690 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	137,932,684 - 137,947,368 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	139,702,687 - 139,717,377 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	139,709,784 - 139,724,468 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	140,642,865 - 140,657,759 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	140,642,885 - 140,657,745 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	144,433,445 - 144,448,324 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	142,260,560 - 142,275,435 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	142,265,780 - 142,280,604 (-)	NCBI
Celera	5	133,764,543 - 133,779,074 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

cryptorchidism (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

intellectual disability (ISO)

microcephaly (ISO)

primary autosomal recessive microcephaly 15 (ISO)

speech disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

15-acetyldeoxynivalenol (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,4,7,8-Pentachlorodibenzofuran (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-hydroxypropanoic acid (ISO)

2-palmitoylglycerol (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,3',5-triiodo-L-thyronine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

Benzo[k]fluoranthene (ISO)

beta-naphthoflavone (ISO)

bexarotene (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromobenzene (EXP)

buspirone (EXP)

butanal (ISO)

C60 fullerene (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

choline (ISO)

chrysene (ISO)

ciguatoxin CTX1B (ISO)

clobetasol (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

dextran sulfate (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

diclofenac (ISO)

dioxygen (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

fenofibrate (ISO)

folic acid (ISO)

fructose (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glucose (ISO)

glycidol (EXP)

glyphosate (ISO)

GW 4064 (ISO)

inulin (ISO)

iron dichloride (ISO)

ketamine (EXP)

L-methionine (ISO)

levofloxacin (EXP)

lipopolysaccharide (ISO)

lysophosphatidylcholine (ISO)

malathion (ISO)

melphalan (ISO)

metformin (EXP)

methimazole (EXP)

methotrexate (ISO)

methylisothiazolinone (ISO)

N-nitrosodiethylamine (ISO)

N-Nitrosopyrrolidine (ISO)

naphthalene (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

obeticholic acid (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (EXP)

pentanal (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenformin (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sevoflurane (EXP)

sodium arsenite (ISO)

sodium dichromate (EXP)

succimer (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (ISO)

trimellitic anhydride (ISO)

Triptolide (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

brain development (ISO)

carbohydrate transport (IEA)

cellular response to starvation (ISO)

cognition (ISO)

embryonic brain development (ISO)

energy homeostasis (ISO)

establishment of blood-brain barrier (ISO)

establishment of blood-retinal barrier (ISO)

fatty acid transport (IBA,ISO)

hippocampus development (ISO)

lipid transport across blood-brain barrier (IBA,ISO)

long-chain fatty acid transport (ISO)

lysophospholipid translocation (IBA,ISO)

lysophospholipid transport (ISO)

maintenance of blood-brain barrier (ISO)

motor behavior (ISO)

negative regulation of fatty acid beta-oxidation (ISO)

photoreceptor cell morphogenesis (ISO)

photoreceptor cell outer segment organization (ISO)

positive regulation of cell growth (ISO)

positive regulation of triglyceride biosynthetic process (ISO)

regulation of dendrite development (ISO)

regulation of multicellular organism growth (ISO)

regulation of neuron projection arborization (ISO)

regulation of phosphatidylcholine metabolic process (ISO)

regulation of phosphatidylethanolamine metabolic process (ISO)

regulation of phosphatidylserine metabolic process (ISO)

retina morphogenesis in camera-type eye (ISO)

retinal pigment epithelium development (ISO)

transcytosis (ISO)

transmembrane transport (IEA)

very-low-density lipoprotein particle assembly (ISO)

Cellular Component

endoplasmic reticulum membrane (IEA)

plasma membrane (IBA,ISO)

Molecular Function

fatty acid transmembrane transporter activity (IBA,ISO)

long-chain fatty acid transmembrane transporter activity (ISO)

lysophosphatidylcholine flippase activity (ISO)

lysophospholipid:sodium symporter activity (IBA,ISO)

oleate transmembrane transporter activity (ISO)

protein binding (ISO)

symporter activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:23209793	PMID:24828040	PMID:24828044	PMID:26005865	PMID:26005868	PMID:26945070	PMID:27008858	PMID:30074985	PMID:31907728	PMID:36631446	PMID:37458379

Genomics

Comparative Map Data

Mfsd2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	140,510,933 - 140,525,828 (-)	NCBI		GRCr8
mRatBN7.2	5	135,225,801 - 135,240,744 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	135,225,816 - 135,240,690 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	137,932,684 - 137,947,368 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	139,702,687 - 139,717,377 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	139,709,784 - 139,724,468 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	140,642,865 - 140,657,759 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	140,642,885 - 140,657,745 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	144,433,445 - 144,448,324 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	142,260,560 - 142,275,435 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	142,265,780 - 142,280,604 (-)	NCBI
Celera	5	133,764,543 - 133,779,074 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

MFSD2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	39,955,145 - 39,969,956 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	39,955,112 - 39,969,968 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	40,420,817 - 40,435,628 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	40,193,397 - 40,208,215 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	38,702,422 - 38,717,260 (+)	NCBI		Celera
Cytogenetic Map	1	p34.2	NCBI
HuRef	1	38,539,329 - 38,554,171 (+)	NCBI		HuRef
CHM1_1	1	40,536,427 - 40,551,270 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	39,824,591 - 39,839,402 (+)	NCBI		T2T-CHM13v2.0

Mfsd2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	122,840,643 - 122,855,844 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	122,840,643 - 122,854,981 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	122,946,850 - 122,961,194 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	122,946,850 - 122,961,188 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	122,624,093 - 122,638,431 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	122,449,153 - 122,463,473 (-)	NCBI		MGSCv36	mm8
Celera	4	121,276,713 - 121,291,009 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	57.34	NCBI

Mfsd2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	17,430,219 - 17,443,830 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	17,430,850 - 17,443,830 (+)	NCBI	ChiLan1.0	ChiLan1.0

MFSD2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	186,853,107 - 186,867,856 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	185,990,715 - 186,005,462 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	39,244,438 - 39,259,156 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	40,569,706 - 40,584,438 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	40,569,706 - 40,584,438 (+)	Ensembl	panpan1.1		panPan2

MFSD2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	2,966,433 - 2,979,030 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	2,966,461 - 2,978,968 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	3,223,537 - 3,236,132 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	3,053,922 - 3,066,514 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	3,053,950 - 3,066,453 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	2,960,820 - 2,973,412 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	3,020,725 - 3,033,317 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	3,037,135 - 3,049,729 (-)	NCBI		UU_Cfam_GSD_1.0

Mfsd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	55,966,002 - 55,978,559 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	21,790,747 - 21,803,360 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	21,790,807 - 21,803,336 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MFSD2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	95,738,969 - 95,753,245 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	95,738,961 - 95,753,245 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	88,931,112 - 88,945,386 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MFSD2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	92,926,217 - 92,941,191 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	92,926,067 - 92,941,159 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	23,896,232 - 23,911,104 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mfsd2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	22,422,423 - 22,435,416 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	22,422,520 - 22,435,332 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mfsd2a
99 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	63
Count of miRNA genes:	58
Interacting mature miRNAs:	63
Transcripts:	ENSRNOT00000019080
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
631527	Tls1	T-lymphoma susceptibility QTL 1	0	0.001	thymus integrity trait (VT:0010555)	post-insult time to onset of T-cell lymphoma (CMO:0001907)	5	90450144	135450144	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	120740824	143608494	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1300122	Wbc1	White blood cell count QTL 1	2.75		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	5	125392826	139989768	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	129132428	143070159	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
7411722	Strs6	Sensitivity to stroke QTL 6	3.9		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	5	134972980	138113556	Rat

Markers in Region

BF400287

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	135,239,524 - 135,239,728 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	140,656,586 - 140,656,789	NCBI	Rnor6.0
Rnor_5.0	5	144,447,166 - 144,447,369	UniSTS	Rnor5.0
RGSC_v3.4	5	142,274,276 - 142,274,479	UniSTS	RGSC3.4
Celera	5	133,777,915 - 133,778,118	UniSTS
RH 3.4 Map	5	890.0	UniSTS
Cytogenetic Map	5	q36	UniSTS

BF387250

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	135,239,532 - 135,239,728 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	140,656,594 - 140,656,789	NCBI	Rnor6.0
Rnor_5.0	5	144,447,174 - 144,447,369	UniSTS	Rnor5.0
RGSC_v3.4	5	142,274,284 - 142,274,479	UniSTS	RGSC3.4
Celera	5	133,777,923 - 133,778,118	UniSTS
Cytogenetic Map	5	q36	UniSTS

BF404032

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	135,239,268 - 135,239,420 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	140,656,330 - 140,656,481	NCBI	Rnor6.0
Rnor_5.0	5	144,446,910 - 144,447,061	UniSTS	Rnor5.0
RGSC_v3.4	5	142,274,020 - 142,274,171	UniSTS	RGSC3.4
Celera	5	133,777,659 - 133,777,810	UniSTS
RH 3.4 Map	5	874.1	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			14	14		14			69		4
Low	3	14	17	9	18	9	1	1	5	22	37	11	1
Below cutoff		12	26	18	1	18	6	8		8			6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC106432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000019080 ⟹ ENSRNOP00000019080

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	135,225,816 - 135,240,690 (-)	Ensembl
Rnor_6.0 Ensembl	5	140,642,885 - 140,657,745 (-)	Ensembl

RefSeq Acc Id:

NM_001106683 ⟹ NP_001100153

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	140,510,938 - 140,525,817 (-)	NCBI
mRatBN7.2	5	135,225,801 - 135,240,690 (-)	NCBI
Rnor_6.0	5	140,642,870 - 140,657,745 (-)	NCBI
Rnor_5.0	5	144,433,445 - 144,448,324 (-)	NCBI
RGSC_v3.4	5	142,260,560 - 142,275,435 (-)	RGD
Celera	5	133,764,543 - 133,779,074 (-)	RGD

Sequence:

show sequence

GTTTTCCTCGCCGGCGTTGCTGGTTTGCTAAGAGCTAGCGAACAGAGAGAGTAGTAGCTGCGGC
TGCGCCTAGGACCGGAGCCTCAGGAGAGTGCCGGCCGGCAGAACACTAGAGCATCCCGGCGTCC
GGGTCCCAGGCGGCGTGGCCCGCGGGTCATGGCCAAAGGAGAGGGCGCCGAGAGCGGTTCCGCG
GCGGGGCTGCTCCCCACCGGCATCCTCCAAGCCAGCGAACGACCAGCCCAGGTGAAGAAGGAAC
CAAAAAAGAAGCAGCAACTGTCCATTTGCAATAAGCTTTGCTATGCGGTTGGAGGGGCCCCATA
CCAGTTGACCGGCTGCGCGCTGGGATTCTTCCTGCAGATCTACCTGTTGGATGTGGCTAAGGTG
GAGCCACTCCCTGCTTCCATTATCCTTTTCGTGGGCCGAGCGTGGGATGCCTTCACTGACCCTC
TCGTGGGCTTCTGCATCAGCAAGTCCTCCTGGACCCGCCTGGGCCGCCTCATGCCCTGGATCAT
CTTCTCCACTCCTCTGGCCATCATTGCTTACTTTCTCATCTGGTTTGTGCCTGACTTCCCATCA
GGGACAGAAAGTTCGCACGGGTTCCTTTGGTACCTGCTTTTCTATTGCCTCTTTGAGACACTGG
TCACGTGCTTCCACGTTCCCTACTCAGCGCTCACCATGTTCATCAGTACCGAGCAGAGTGAGCG
TGACTCCGCCACTGCCTATAGGATGACTGTGGAGGTTCTGGGCACAGTGATAGGCACAGCGATC
CAAGGACAAATTGTGGGCCAAGCCAAGGCACCTTGTCTCCAGGACCAGAATGGCTCTGCAGTGG
CCTCAGAAGTTGTCAATCGTACCCAGAGCACTGCCTCCCTCAAAGAAACGCAAAATGCATACCT
GCTGGCAGCAGGGATCATCGCCTCCATCTACGTCATCTGTGCCGTCATTCTGATTTTAGGCGTG
CGGGAGCAGAGAGAACCCTACGAGGCCCAGCAGGCCGAGTCAATGCCCTTCTTTCAGGGCCTCC
GGCTGGTTATGAGTCATGGCCCCTATGTCAAGCTCATTGCCGGCTTCCTTTTTACCTCCCTGGC
TTTCATGCTGGTAGAAGGTAATTTTGCCTTGTTCTGCACCTACACCTTGGGCTTCCGGAACGAG
TTCCAGAACCTCCTCCTGGCCATCATGCTCTCGGCCACATTCACCATCCCCATCTGGCAATGGT
TCCTAACCCGGTTTGGCAAGAAGACGGCTGTATACGTTGGGATCTCTTCTGCAGTTCCTTTTCT
CATCTTGGTGGCCCTCATGAAGAGTAATCTAATCGTCACTTACGTGGTGGCCATAGCAGCTGGT
GTCAGTGTAGCAGCTGCCTTCTTACTACCATGGTCCATGCTGCCTGATGTTATCGATGACTTCC
ACCTGAAACACCCTCACTCCCCTGGCACGGAGCCCATCTTCTTCTCCTTCTATGTCTTCTTCAC
CAAGTTTGCCTCTGGAGTCTCACTGGGTGTCTCTACCCTCAGTCTCGACTTTGCTAAGTACCAG
ACGCAGGGGTGCTCCCAGCCAGAAGAGGTCAAGTTTACACTGAAGATGCTGGTGACCATGGCTC
CTATCATCCTCATCCTGCTGGGCCTGCTGCTCTTCAAGCTGTACCCCATTGATGAGGAGAAGCG
GCGACAGAACAAGAAAGCTCTGCAGGCTTTACGAGATGAAGCCAGCAGCTCAGGCTGCTCGGAT
ACAGACTCCACAGAGCTGGCCAGCATTCTCTAGGACTTGCCGGGTTGCCTGAAGCCACCGCACA
AAGGACCTGGGGCACCAGGTAGCATTAGGGCATGGGATCTTTTTGCCCTTGCACTGAGCAGCTG
TTCTTCCTATGTCAAGACAGGGACCAAGGACTGGAGGGTGAGCAGCCCAGGACATCTGTGCTCA
CTGCTGGGCTGGCCGTTCTGTAAACTCCTCACTGCCCGCCCATGGGCCAAGCCCTAGGGCTGCT
ACTGTGAATATGCCAAGGACTGACTGGGCCTAGCTCGGAACACTAATGTAGAAACGTTTTATAC
AGAGACTAATTAATAACTTAATGACTATGTATATAGGGATGTGTGTATGTATATGTCTGTGAGG
TATTAATGTTATTAATTTTCATAAAAACTGGAAAC

hide sequence

RefSeq Acc Id:

XM_006238792 ⟹ XP_006238854

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	140,510,933 - 140,525,826 (-)	NCBI
mRatBN7.2	5	135,225,948 - 135,240,697 (-)	NCBI
Rnor_6.0	5	140,642,865 - 140,657,759 (-)	NCBI
Rnor_5.0	5	144,433,445 - 144,448,324 (-)	NCBI

Sequence:

show sequence

GGGCGTGCAAAGGAGTTTTCCTCGCCGGCGTTGCTGGTTTGCTAAGAGCTAGCGAACAGAGAGA
GTAGTAGCTGCGGCTGCGCCTAGGACCGGAGCCTCAGGAGAGTGCCGGCCGGCAGAACACTAGA
GCATCCCGGCGTCCGGGTCCCAGGCGGCGTGGCCCGCGGGTCATGGCCAAAGGAGAGGGCGCCG
AGAGCGGTTCCGCGGCGGGGCTGCTCCCCACCGGCATCCTCCAAGCCAGCGAACGACCAGCCCA
GGTGAAGGAACCAAAAAAGAAGCAGCAACTGTCCATTTGCAATAAGCTTTGCTATGCGGTTGGA
GGGGCCCCATACCAGTTGACCGGCTGCGCGCTGGGATTCTTCCTGCAGATCTACCTGTTGGATG
TGGCTAAGGTGGAGCCACTCCCTGCTTCCATTATCCTTTTCGTGGGCCGAGCGTGGGATGCCTT
CACTGACCCTCTCGTGGGCTTCTGCATCAGCAAGTCCTCCTGGACCCGCCTGGGCCGCCTCATG
CCCTGGATCATCTTCTCCACTCCTCTGGCCATCATTGCTTACTTTCTCATCTGGTTTGTGCCTG
ACTTCCCATCAGGGACAGAAAGTTCGCACGGGTTCCTTTGGTACCTGCTTTTCTATTGCCTCTT
TGAGACACTGGTCACGTGCTTCCACGTTCCCTACTCAGCGCTCACCATGTTCATCAGTACCGAG
CAGAGTGAGCGTGACTCCGCCACTGCCTATAGGATGACTGTGGAGGTTCTGGGCACAGTGATAG
GCACAGCGATCCAAGGACAAATTGTGGGCCAAGCCAAGGCACCTTGTCTCCAGGACCAGAATGG
CTCTGCAGTGGCCTCAGAAGTTGTCAATCGTACCCAGAGCACTGCCTCCCTCAAAGAAACGCAA
AATGCATACCTGCTGGCAGCAGGGATCATCGCCTCCATCTACGTCATCTGTGCCGTCATTCTGA
TTTTAGGCGTGCGGGAGCAGAGAGAACCCTACGAGGCCCAGCAGGCCGAGTCAATGCCCTTCTT
TCAGGGCCTCCGGCTGGTTATGAGTCATGGCCCCTATGTCAAGCTCATTGCCGGCTTCCTTTTT
ACCTCCCTGGCTTTCATGCTGGTAGAAGGTAATTTTGCCTTGTTCTGCACCTACACCTTGGGCT
TCCGGAACGAGTTCCAGAACCTCCTCCTGGCCATCATGCTCTCGGCCACATTCACCATCCCCAT
CTGGCAATGGTTCCTAACCCGGTTTGGCAAGAAGACGGCTGTATACGTTGGGATCTCTTCTGCA
GTTCCTTTTCTCATCTTGGTGGCCCTCATGAAGAGTAATCTAATCGTCACTTACGTGGTGGCCA
TAGCAGCTGGTGTCAGTGTAGCAGCTGCCTTCTTACTACCATGGTCCATGCTGCCTGATGTTAT
CGATGACTTCCACCTGAAACACCCTCACTCCCCTGGCACGGAGCCCATCTTCTTCTCCTTCTAT
GTCTTCTTCACCAAGTTTGCCTCTGGAGTCTCACTGGGTGTCTCTACCCTCAGTCTCGACTTTG
CTAAGTACCAGACGCAGGGGTGCTCCCAGCCAGAAGAGGTCAAGTTTACACTGAAGATGCTGGT
GACCATGGCTCCTATCATCCTCATCCTGCTGGGCCTGCTGCTCTTCAAGCTGTACCCCATTGAT
GAGGAGAAGCGGCGACAGAACAAGAAAGCTCTGCAGGCTTTACGAGATGAAGCCAGCAGCTCAG
GCTGCTCGGATACAGACTCCACAGAGCTGGCCAGCATTCTCTAGGACTTGCCGGGTTGCCTGAA
GCCACCGCACAAAGGACCTGGGGCACCAGGTAGCATTAGGGCATGGGATCTTTTTGCCCTTGCA
CTGAGCAGCTGTTCTTCCTATGTCAAGACAGGGACCAAGGACTGGAGGGTGAGCAGCCCAGGAC
ATCTGTGCTCACTGCTGGGCTGGCCGTTCTGTAAACTCCTCACTGCCCGCCCATGGGCCAAGCC
CTAGGGCTGCTACTGTGAATATGCCAAGGACTGACTGGGCCTAGCTCGGAACACTAATGTAGAA
ACGTTTTATACAGAGACTAATTAATAACTTAATGACTATGTATATAGGGATGTGTGTATGTATA
TGTCTGTGAGGTATTAATGTTATTAATTTTCATAAAAACTGGAAACAAAAA

hide sequence

RefSeq Acc Id:

XM_039109607 ⟹ XP_038965535

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	140,510,933 - 140,525,826 (-)	NCBI
mRatBN7.2	5	135,225,948 - 135,240,697 (-)	NCBI

RefSeq Acc Id:

XM_039109609 ⟹ XP_038965537

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	140,514,694 - 140,525,828 (-)	NCBI
mRatBN7.2	5	135,229,558 - 135,240,744 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100153	(Get FASTA)	NCBI Sequence Viewer
	XP_006238854	(Get FASTA)	NCBI Sequence Viewer
	XP_038965535	(Get FASTA)	NCBI Sequence Viewer
	XP_038965537	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61915	(Get FASTA)	NCBI Sequence Viewer
	EDL80363	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019080
	ENSRNOP00000019080.4

RefSeq Acc Id:

NP_001100153 ⟸ NM_001106683

- UniProtKB:

B1WBW6 (UniProtKB/TrEMBL), F7F9H0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKGEGAESGSAAGLLPTGILQASERPAQVKKEPKKKQQLSICNKLCYAVGGAPYQLTGCALGF
FLQIYLLDVAKVEPLPASIILFVGRAWDAFTDPLVGFCISKSSWTRLGRLMPWIIFSTPLAIIA
YFLIWFVPDFPSGTESSHGFLWYLLFYCLFETLVTCFHVPYSALTMFISTEQSERDSATAYRMT
VEVLGTVIGTAIQGQIVGQAKAPCLQDQNGSAVASEVVNRTQSTASLKETQNAYLLAAGIIASI
YVICAVILILGVREQREPYEAQQAESMPFFQGLRLVMSHGPYVKLIAGFLFTSLAFMLVEGNFA
LFCTYTLGFRNEFQNLLLAIMLSATFTIPIWQWFLTRFGKKTAVYVGISSAVPFLILVALMKSN
LIVTYVVAIAAGVSVAAAFLLPWSMLPDVIDDFHLKHPHSPGTEPIFFSFYVFFTKFASGVSLG
VSTLSLDFAKYQTQGCSQPEEVKFTLKMLVTMAPIILILLGLLLFKLYPIDEEKRRQNKKALQA
LRDEASSSGCSDTDSTELASIL

hide sequence

RefSeq Acc Id:

XP_006238854 ⟸ XM_006238792

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAKGEGAESGSAAGLLPTGILQASERPAQVKEPKKKQQLSICNKLCYAVGGAPYQLTGCALGFF
LQIYLLDVAKVEPLPASIILFVGRAWDAFTDPLVGFCISKSSWTRLGRLMPWIIFSTPLAIIAY
FLIWFVPDFPSGTESSHGFLWYLLFYCLFETLVTCFHVPYSALTMFISTEQSERDSATAYRMTV
EVLGTVIGTAIQGQIVGQAKAPCLQDQNGSAVASEVVNRTQSTASLKETQNAYLLAAGIIASIY
VICAVILILGVREQREPYEAQQAESMPFFQGLRLVMSHGPYVKLIAGFLFTSLAFMLVEGNFAL
FCTYTLGFRNEFQNLLLAIMLSATFTIPIWQWFLTRFGKKTAVYVGISSAVPFLILVALMKSNL
IVTYVVAIAAGVSVAAAFLLPWSMLPDVIDDFHLKHPHSPGTEPIFFSFYVFFTKFASGVSLGV
STLSLDFAKYQTQGCSQPEEVKFTLKMLVTMAPIILILLGLLLFKLYPIDEEKRRQNKKALQAL
RDEASSSGCSDTDSTELASIL

hide sequence

RefSeq Acc Id:

ENSRNOP00000019080 ⟸ ENSRNOT00000019080

RefSeq Acc Id:	XP_038965535 ⟸ XM_039109607
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038965537 ⟸ XM_039109609
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WBW6-F1-model_v2	AlphaFold	B1WBW6	1-534	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694000

Promoter ID:

EPDNEW_R4525

Type:

multiple initiation site

Name:

Mfsd2a_1

Description:

major facilitator superfamily domain containing 2A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	140,657,746 - 140,657,806	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310174	AgrOrtholog
BioCyc Gene	G2FUF-40027	BioCyc
Ensembl Genes	ENSRNOG00000014008	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019080	ENTREZGENE
	ENSRNOT00000019080.8	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8369688	IMAGE-MGC_LOAD
InterPro	MFS_2	UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/TrEMBL
KEGG Report	rno:298504	UniProtKB/TrEMBL
MGC_CLONE	MGC:187650	IMAGE-MGC_LOAD
NCBI Gene	298504	ENTREZGENE
PANTHER	PTHR11328	UniProtKB/TrEMBL
	SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1	UniProtKB/TrEMBL
Pfam	MFS_2	UniProtKB/TrEMBL
PhenoGen	Mfsd2a	PhenoGen
RatGTEx	ENSRNOG00000014008	RatGTEx
Superfamily-SCOP	MFS_gen_substrate_transporter	UniProtKB/TrEMBL
UniProt	B1WBW6	ENTREZGENE, UniProtKB/TrEMBL
	F7F9H0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-10-27	Mfsd2a	MFSD2 lysolipid transporter A, lysophospholipid	Mfsd2a	major facilitator superfamily domain containing 2A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-02	Mfsd2a	major facilitator superfamily domain containing 2A	Mfsd2	major facilitator superfamily domain containing 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Mfsd2	major facilitator superfamily domain containing 2	RGD1310174_predicted	hypothetical LOC298504 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1310174_predicted	hypothetical LOC298504 (predicted)	LOC298504_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC298504_predicted	hypothetical LOC298504 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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