Gene: Plk4 (polo-like kinase 4) Rattus norvegicus
Analyze
Symbol: Plk4
Name: polo-like kinase 4
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN centriole replication (ortholog); de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (ortholog); positive regulation of centriole replication (ortholog); ASSOCIATED WITH Dwarfism (ortholog); Eye Diseases, Hereditary (ortholog); Microcephaly (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); cytosol (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC310344; PLK-4; polo-like kinase 4 (Drosophila); serine/threonine-protein kinase PLK4; serine/threonine-protein kinase Sak
Orthologs:
Homo sapiens (human) : PLK4 (polo like kinase 4)  HGNC
Mus musculus (house mouse) : Plk4 (polo-like kinase 4)  MGI
Pan paniscus (bonobo/pygmy chimpanzee) : PLK4 (polo like kinase 4)
Canis lupus familiaris (dog) : PLK4 (polo like kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk4 (polo like kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02127,686,911 - 127,705,518 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02147,289,950 - 147,308,585 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42127,760,508 - 127,779,640 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12127,710,374 - 127,729,098 (+)NCBI
Celera2118,710,474 - 118,728,860 (+)NCBI
Cytogenetic Map2q25NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Plk4
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1305390
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-03-14
Status: ACTIVE