Gene: Plk4 (polo-like kinase 4) Rattus norvegicus
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Symbol: Plk4
Name: polo-like kinase 4
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN centriole replication (ortholog); de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (ortholog); positive regulation of centriole replication (ortholog); ASSOCIATED WITH Microcephaly and Chorioretinopathy, Autosomal Recessive, 2 (ortholog); Dwarfism (ortholog); Eye Diseases, Hereditary (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); cytosol (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC310344; PLK-4; polo-like kinase 4 (Drosophila); serine/threonine-protein kinase PLK4; serine/threonine-protein kinase Sak
Orthologs:
Homo sapiens (human) : PLK4 (polo like kinase 4)  HGNC  AGR
Mus musculus (house mouse) : Plk4 (polo like kinase 4)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Plk4 (polo like kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PLK4 (polo like kinase 4)
Canis lupus familiaris (dog) : PLK4 (polo like kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk4 (polo like kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02127,686,911 - 127,705,518 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02147,289,950 - 147,308,585 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42127,760,508 - 127,779,640 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12127,710,374 - 127,729,098 (+)NCBI
Celera2118,710,474 - 118,728,860 (+)NCBI
Cytogenetic Map2q25NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Plk4
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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RGD Object Information
RGD ID: 1305390
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE