Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | ISO | RGD:1351174 | 6480464 | Estradiol promotes the reaction [NR1I2 protein binds to MED1 protein] | CTD | PMID:15650019 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1617613 | 6480464 | Tetrachlorodibenzodioxin affects the expression of MED1 mRNA | CTD | PMID:20702594 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1617613 | 6480464 | Tetrachlorodibenzodioxin affects the expression of MED1 mRNA | CTD | PMID:20702594 PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MED1 mRNA | CTD | PMID:22298810 | 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | RGD:1617613 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl affects the expression of MED1 mRNA | CTD | PMID:20702594 | 4-vinylcyclohexene dioxide | increases expression | ISO | RGD:1617613 | 6480464 | 4-vinyl-1-cyclohexene dioxide results in increased expression of MED1 mRNA | CTD | PMID:20829426 | all-trans-retinoic acid | affects response to substance | ISO | RGD:1617613 | 6480464 | MED1 protein affects the susceptibility to Tretinoin | CTD | PMID:16723356 | all-trans-retinoic acid | increases expression | ISO | RGD:1617613 | 6480464 | Tretinoin results in increased expression of MED1 mRNA | CTD | PMID:16324150 | all-trans-retinoic acid | multiple interactions | ISO | RGD:1617613 | 6480464 | MED1 protein affects the reaction [Tretinoin results in increased expression of RARB mRNA alternative form] | CTD | PMID:16723356 | all-trans-retinoic acid | multiple interactions | ISO | RGD:1351174 | 6480464 | Tretinoin promotes the reaction [MED1 protein binds to HAS2 promoter] | CTD | PMID:17307735 | arsenic atom | decreases expression | ISO | RGD:1617613 | 6480464 | Arsenic results in decreased expression of MED1 mRNA | CTD | PMID:19654921 | benzo[a]pyrene | multiple interactions | ISO | RGD:1617613 | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to MED1 promoter] | CTD | PMID:19654925 | benzo[a]pyrene | increases expression | ISO | RGD:1617613 | 6480464 | Benzo(a)pyrene results in increased expression of MED1 mRNA | CTD | PMID:20127859 PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGD:1617613 | 6480464 | Benzo(a)pyrene results in increased expression of MED1 mRNA | CTD | PMID:20127859 | bisphenol A | multiple interactions | ISO | RGD:1351174 | 6480464 | bisphenol A promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein] | CTD | PMID:22214767 | bisphenol A | increases expression | ISO | RGD:1617613 | 6480464 | bisphenol A results in increased expression of MED1 mRNA; more ... | CTD | PMID:14664715 | calcitriol | multiple interactions | ISO | RGD:1351174 | 6480464 | Calcitriol promotes the reaction [[VDR protein binds to MED1 protein] which binds to CYP24A1 promoter] | CTD | PMID:15919092 | calcitriol | multiple interactions | ISO | RGD:1617613 | 6480464 | MED1 protein promotes the reaction [Calcitriol results in increased activity of VDR protein] | CTD | PMID:16324150 | calcitriol | increases expression | ISO | RGD:1617613 | 6480464 | Calcitriol results in increased expression of MED1 mRNA | CTD | PMID:16324150 | calcitriol | multiple interactions | ISO | RGD:1617613 | 6480464 | Calcitriol promotes the reaction [MED1 protein binds to CYP24A1 promoter]; more ... | CTD | PMID:15647825 | calcitriol | affects localization | ISO | RGD:1617613 | 6480464 | Calcitriol affects the localization of MED1 protein | CTD | PMID:15647825 | carmustine | decreases expression | ISO | RGD:1351174 | 6480464 | Carmustine results in decreased expression of MED1 mRNA | CTD | PMID:15980968 | chloroethene | decreases expression | ISO | RGD:1617613 | 6480464 | Vinyl Chloride results in decreased expression of MED1 mRNA | CTD | PMID:18579281 | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of MED1 mRNA | CTD | PMID:23125180 | chlorpyrifos | decreases expression | ISO | RGD:1617613 | 6480464 | Chlorpyrifos results in decreased expression of MED1 mRNA | CTD | PMID:20350560 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of MED1 mRNA | CTD | PMID:18668222 | cisplatin | multiple interactions | ISO | RGD:1351174 | 6480464 | Cisplatin promotes the reaction [NR1I2 protein binds to MED1 protein] | CTD | PMID:15650019 | copper(2+) sulfate | decreases expression | ISO | RGD:1617613 | 6480464 | Copper Sulfate results in decreased expression of MED1 mRNA | CTD | PMID:18579281 | dexamethasone | affects response to substance | ISO | RGD:1617613 | 6480464 | MED1 affects the susceptibility to Dexamethasone | CTD | PMID:19630272 | dibutyl phthalate | decreases expression | ISO | RGD:1617613 | 6480464 | Dibutyl Phthalate results in decreased expression of MED1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of MED1 mRNA | CTD | PMID:21266533 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of MED1 gene | CTD | PMID:22079235 | methoxychlor | increases expression | ISO | RGD:1617613 | 6480464 | Methoxychlor results in increased expression of MED1 mRNA | CTD | PMID:20829426 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:1351174 | 6480464 | mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to MED1 protein] | CTD | PMID:20123618 | N-nitrosodiethylamine | increases response to substance | ISO | RGD:1617613 | 6480464 | MED1 protein results in increased susceptibility to Diethylnitrosamine | CTD | PMID:20007298 | okadaic acid | multiple interactions | ISO | RGD:1351174 | 6480464 | [1,25-dihydroxyvitamin D co-treated with Okadaic Acid] promotes the reaction [VDR protein mutant form binds to MED1 protein] | CTD | PMID:16059639 | paclitaxel | multiple interactions | ISO | RGD:1351174 | 6480464 | Paclitaxel promotes the reaction [NR1I2 protein binds to MED1 protein] | CTD | PMID:15650019 | pentobarbital | multiple interactions | ISO | RGD:1617613 | 6480464 | MED1 protein affects the localization of [Pentobarbital binds to NR1I3 protein] | CTD | PMID:16828057 | phenobarbital | increases response to substance | ISO | RGD:1617613 | 6480464 | MED1 gene mutant form results in increased susceptibility to Phenobarbital | CTD | PMID:16109766 | phenobarbital | increases localization | ISO | RGD:1617613 | 6480464 | Phenobarbital results in increased localization of MED1 protein | CTD | PMID:16109766 | phenobarbital | multiple interactions | ISO | RGD:1617613 | 6480464 | MED1 protein promotes the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]; more ... | CTD | PMID:16109766 | phthalic acid | multiple interactions | ISO | RGD:1351174 | 6480464 | phthalic acid promotes the reaction [NR1I2 protein binds to MED1 protein] | CTD | PMID:15650019 | pirinixic acid | multiple interactions | ISO | RGD:1351174 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MED1 mRNA | CTD | PMID:19710929 | pirinixic acid | multiple interactions | ISO | RGD:1617613 | 6480464 | MED1 protein promotes the reaction [pirinixic acid affects the localization of NR1I3 protein] | CTD | PMID:17962186 | pirinixic acid | multiple interactions | ISO | RGD:1617613 | 6480464 | pirinixic acid promotes the reaction [PPARA protein binds to MED1 protein] | CTD | PMID:20123618 | pirinixic acid | multiple interactions | ISO | RGD:1351174 | 6480464 | pirinixic acid promotes the reaction [PPARA protein binds to MED1 protein] | CTD | PMID:20123618 | pirinixic acid | increases response to substance | ISO | RGD:1617613 | 6480464 | MED1 protein results in increased susceptibility to pirinixic acid | CTD | PMID:20007298 | rifampicin | multiple interactions | ISO | RGD:1351174 | 6480464 | Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein] | CTD | PMID:22214767 | rifampicin | multiple interactions | ISO | RGD:1351174 | 6480464 | Rifampin promotes the reaction [MED1 protein binds to HNF4A protein] | CTD | PMID:21292004 | tunicamycin | decreases expression | ISO | RGD:1617613 | 6480464 | Tunicamycin results in decreased expression of MED1 mRNA | CTD | PMID:17127020 | | |||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process











