Gene: Ins2 (insulin 2) Rattus norvegicus
Symbol: Ins2
Name: insulin 2
Description: ENCODES a protein that exhibits protease binding; protein complex binding; hormone activity (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of protein kinase B activity (ortholog); acute-phase response (ortholog); PARTICIPATES IN altered insulin signaling pathway; forkhead class A signaling pathway; gliclazide pharmacodynamics pathway; ASSOCIATED WITH Alzheimer Disease; Diabetic Nephropathies; Hypertension; FOUND IN extracellular space; secretory granule; cytoplasm (ortholog); INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: insulin-2
Homo sapiens : INS (insulin)  HGNC
Mus musculus : Ins2 (insulin II)  MGI
more info ...
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01215,856,967 - 215,858,034-NCBI
Rat Cytogenetic Map1q41 NCBI
RGSC Genome Assembly v5.01222,751,786 - 222,756,821-NCBI
RGSC Genome Assembly v3.41202,935,548 - 202,936,379-NCBI
Rat Celera Assembly1195,461,309 - 195,462,376-NCBI
Genome Assembly 3.11203,123,613 - 203,124,445-NCBI

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Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
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Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ins2
Entrez Gene
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RGD Object Information
RGD ID: 2916
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-11-10
Status: ACTIVE