Recql (RecQ like helicase) - Rat Genome Database

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Gene: Recql (RecQ like helicase) Rattus norvegicus
Analyze
Symbol: Recql
Name: RecQ like helicase
RGD ID: 1311071
Description: Predicted to enable DNA helicase activity and DNA/DNA annealing activity. Predicted to be involved in DNA unwinding involved in DNA replication; double-strand break repair via homologous recombination; and replication fork processing. Predicted to be located in nucleoplasm. Predicted to be active in chromosome and cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and pancreatic cancer. Orthologous to human RECQL (RecQ like helicase); INTERACTS WITH 2,6-dinitrotoluene; acrylamide; allethrin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent DNA helicase Q1; DNA-dependent ATPase Q1; LOC312824; RecQ helicase-like; RecQ protein-like; RecQ protein-like (DNA helicase Q1-like); recQ protein-like 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,039,351 - 177,063,968 (-)NCBIGRCr8
mRatBN7.24175,308,337 - 175,332,965 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,304,117 - 175,332,945 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4181,603,185 - 181,627,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,387,454 - 177,411,941 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,008,012 - 176,032,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,581,892 - 176,606,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,581,897 - 176,606,382 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04240,795,675 - 240,820,290 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44179,927,255 - 179,951,742 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14180,172,380 - 180,196,866 (-)NCBI
Celera4163,841,046 - 163,865,533 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
allethrin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
clofibric acid  (EXP)
cocaine  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
FR900359  (ISO)
glafenine  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
kojic acid  (ISO)
levonorgestrel  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
piroxicam  (ISO)
propanal  (ISO)
pyrethrins  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
Testosterone propionate  (ISO)
testosterone undecanoate  (ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IBA,IEA)
cytoplasm  (IBA,IEA)
mediator complex  (IEA)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Single nucleotide polymorphism in RECQL and survival in resectable pancreatic adenocarcinoma. Cotton RT, etal., HPB (Oxford). 2009;11(5):435-44.
2. Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models. Futami K, etal., Cancer Sci. 2008 Jun;99(6):1227-36. Epub 2008 Apr 14.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. Li D, etal., Cancer Res. 2006 Mar 15;66(6):3323-30.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11562355   PMID:12477932   PMID:15489334   PMID:19177149   PMID:19946888  


Genomics

Comparative Map Data
Recql
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,039,351 - 177,063,968 (-)NCBIGRCr8
mRatBN7.24175,308,337 - 175,332,965 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,304,117 - 175,332,945 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4181,603,185 - 181,627,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,387,454 - 177,411,941 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,008,012 - 176,032,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,581,892 - 176,606,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,581,897 - 176,606,382 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04240,795,675 - 240,820,290 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44179,927,255 - 179,951,742 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14180,172,380 - 180,196,866 (-)NCBI
Celera4163,841,046 - 163,865,533 (-)NCBICelera
Cytogenetic Map4q44NCBI
RECQL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,468,910 - 21,501,635 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,468,910 - 21,501,669 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,621,844 - 21,654,569 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,513,965 - 21,545,796 (-)NCBINCBI36Build 36hg18NCBI36
Build 341221,514,353 - 21,545,796NCBI
Celera1226,777,229 - 26,809,985 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1221,395,874 - 21,428,641 (-)NCBIHuRef
CHM1_11221,587,472 - 21,620,203 (-)NCBICHM1_1
T2T-CHM13v2.01221,347,594 - 21,380,648 (-)NCBIT2T-CHM13v2.0
Recql
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396142,296,068 - 142,332,802 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6142,296,068 - 142,332,813 (-)EnsemblGRCm39 Ensembl
GRCm386142,350,342 - 142,387,100 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6142,350,342 - 142,387,087 (-)EnsemblGRCm38mm10GRCm38
MGSCv376142,310,420 - 142,335,607 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366142,319,368 - 142,344,253 (-)NCBIMGSCv36mm8
Celera6145,421,861 - 145,447,035 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map673.91NCBI
Recql
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541317,113,408 - 17,148,708 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541317,115,443 - 17,148,708 (-)NCBIChiLan1.0ChiLan1.0
RECQL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21075,300,616 - 75,333,274 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11275,297,014 - 75,329,247 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01264,796,383 - 64,829,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11267,400,315 - 67,432,724 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1267,400,315 - 67,432,724 (+)Ensemblpanpan1.1panPan2
RECQL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12725,590,326 - 25,636,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2725,590,831 - 25,636,685 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2720,715,583 - 20,761,524 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02725,818,962 - 25,865,150 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2725,819,030 - 25,865,148 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12725,611,850 - 25,658,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02725,634,863 - 25,681,036 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02720,891,461 - 20,937,671 (-)NCBIUU_Cfam_GSD_1.0
Recql
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494587,426,992 - 87,463,355 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365485,362,517 - 5,384,338 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365485,349,878 - 5,384,603 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RECQL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl551,953,451 - 52,003,740 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1551,953,460 - 51,995,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2555,229,615 - 55,272,155 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RECQL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,334,601 - 21,366,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,331,584 - 21,366,979 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606913,777,790 - 13,810,627 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Recql
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475217,185,129 - 17,220,707 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475217,183,624 - 17,220,954 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Recql
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:71
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000065576
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat

Markers in Region
RH130945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24175,308,472 - 175,308,664 (+)MAPPERmRatBN7.2
Rnor_6.04176,582,028 - 176,582,219NCBIRnor6.0
Rnor_5.04240,795,811 - 240,796,002UniSTSRnor5.0
RGSC_v3.44179,927,388 - 179,927,579UniSTSRGSC3.4
Celera4163,841,179 - 163,841,370UniSTS
RH 3.4 Map41031.2UniSTS
Cytogenetic Map4q44UniSTS
BI295118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24175,317,447 - 175,317,546 (+)MAPPERmRatBN7.2
Rnor_6.04176,591,002 - 176,591,100NCBIRnor6.0
Rnor_5.04240,804,785 - 240,804,883UniSTSRnor5.0
RGSC_v3.44179,936,362 - 179,936,460UniSTSRGSC3.4
Celera4163,850,153 - 163,850,251UniSTS
RH 3.4 Map41044.7UniSTS
Cytogenetic Map4q44UniSTS
RH141072  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24175,310,780 - 175,310,971 (+)MAPPERmRatBN7.2
Rnor_6.04176,584,336 - 176,584,526NCBIRnor6.0
Rnor_5.04240,798,119 - 240,798,309UniSTSRnor5.0
RGSC_v3.44179,929,696 - 179,929,886UniSTSRGSC3.4
Celera4163,843,487 - 163,843,677UniSTS
RH 3.4 Map41032.2UniSTS
Cytogenetic Map4q44UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 47 31 19 31 2 3 74 35 41 11 2
Low 6 10 10 10 6 8 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC134270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000065576   ⟹   ENSRNOP00000060671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4175,308,342 - 175,332,828 (-)Ensembl
Rnor_6.0 Ensembl4176,581,897 - 176,606,382 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086365   ⟹   ENSRNOP00000073537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4175,309,759 - 175,322,961 (-)Ensembl
Rnor_6.0 Ensembl4176,582,006 - 176,596,591 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110058   ⟹   ENSRNOP00000077921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4175,308,344 - 175,332,945 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114762   ⟹   ENSRNOP00000085782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4175,304,117 - 175,332,917 (-)Ensembl
RefSeq Acc Id: NM_001012098   ⟹   NP_001012098
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,838 (-)NCBI
mRatBN7.24175,308,340 - 175,332,828 (-)NCBI
Rnor_6.04176,581,895 - 176,606,382 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
RGSC_v3.44179,927,255 - 179,951,742 (-)RGD
Celera4163,841,046 - 163,865,533 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237617   ⟹   XP_006237679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
mRatBN7.24175,308,337 - 175,332,965 (-)NCBI
Rnor_6.04176,581,892 - 176,606,515 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237618   ⟹   XP_006237680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,891 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
Rnor_6.04176,581,892 - 176,606,421 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237619   ⟹   XP_006237681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
mRatBN7.24175,308,337 - 175,332,960 (-)NCBI
Rnor_6.04176,581,892 - 176,606,520 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237620   ⟹   XP_006237682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,883 (-)NCBI
mRatBN7.24175,308,337 - 175,332,858 (-)NCBI
Rnor_6.04176,581,892 - 176,606,420 (-)NCBI
Rnor_5.04240,795,675 - 240,820,290 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107700   ⟹   XP_038963628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,877 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
RefSeq Acc Id: XM_039107701   ⟹   XP_038963629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,891 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
RefSeq Acc Id: XM_039107702   ⟹   XP_038963630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
mRatBN7.24175,308,639 - 175,332,960 (-)NCBI
RefSeq Acc Id: XM_039107703   ⟹   XP_038963631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,891 (-)NCBI
mRatBN7.24175,308,337 - 175,332,867 (-)NCBI
RefSeq Acc Id: XM_063286165   ⟹   XP_063142235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,958 (-)NCBI
RefSeq Acc Id: XM_063286166   ⟹   XP_063142236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
RefSeq Acc Id: XM_063286167   ⟹   XP_063142237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
RefSeq Acc Id: XM_063286169   ⟹   XP_063142239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,875 (-)NCBI
RefSeq Acc Id: XM_063286170   ⟹   XP_063142240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,957 (-)NCBI
RefSeq Acc Id: XM_063286171   ⟹   XP_063142241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,968 (-)NCBI
RefSeq Acc Id: XM_063286172   ⟹   XP_063142242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84177,039,351 - 177,063,873 (-)NCBI
RefSeq Acc Id: NP_001012098   ⟸   NM_001012098
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237681   ⟸   XM_006237619
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237679   ⟸   XM_006237617
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237680   ⟸   XM_006237618
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237682   ⟸   XM_006237620
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y8C0 (UniProtKB/TrEMBL),   A6IMT7 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000060671   ⟸   ENSRNOT00000065576
RefSeq Acc Id: ENSRNOP00000073537   ⟸   ENSRNOT00000086365
RefSeq Acc Id: XP_038963628   ⟸   XM_039107700
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963631   ⟸   XM_039107703
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963629   ⟸   XM_039107701
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963630   ⟸   XM_039107702
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL),   A0A8I6A2E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000085782   ⟸   ENSRNOT00000114762
RefSeq Acc Id: ENSRNOP00000077921   ⟸   ENSRNOT00000110058
RefSeq Acc Id: XP_063142236   ⟸   XM_063286166
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063142241   ⟸   XM_063286171
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142237   ⟸   XM_063286167
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142235   ⟸   XM_063286165
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063142240   ⟸   XM_063286170
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142239   ⟸   XM_063286169
- Peptide Label: isoform X3
- UniProtKB: Q6AYJ1 (UniProtKB/Swiss-Prot),   A6IMT6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142242   ⟸   XM_063286172
- Peptide Label: isoform X4
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYJ1-F1-model_v2 AlphaFold Q6AYJ1 1-621 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693486
Promoter ID:EPDNEW_R4010
Type:initiation region
Name:Recql_1
Description:RecQ like helicase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04176,606,447 - 176,606,507EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311071 AgrOrtholog
BioCyc Gene G2FUF-42495 BioCyc
Ensembl Genes ENSRNOG00000012602 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065576 ENTREZGENE
  ENSRNOT00000065576.3 UniProtKB/Swiss-Prot
  ENSRNOT00000086365.2 UniProtKB/TrEMBL
  ENSRNOT00000110058.1 UniProtKB/TrEMBL
  ENSRNOT00000114762.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114009 IMAGE-MGC_LOAD
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_helicase_ATP-dep_RecQ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RecQ_Zn-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:312824 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93953 IMAGE-MGC_LOAD
NCBI Gene 312824 ENTREZGENE
PANTHER ATP-DEPENDENT DNA HELICASE Q1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA HELICASE RECQ FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DEAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RecQ_Zn_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Recql PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012602 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5S2_RAT UniProtKB/TrEMBL
  A0A8I5Y8C0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2E6 ENTREZGENE, UniProtKB/TrEMBL
  A6IMT6 ENTREZGENE, UniProtKB/TrEMBL
  A6IMT7 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYJ1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Recql  RecQ like helicase  Recql  RecQ helicase-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-03-13 Recql  RecQ helicase-like  Recql  RecQ protein-like (DNA helicase Q1-like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Recql  RecQ protein-like (DNA helicase Q1-like)  Recql  RecQ protein-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Recql  RecQ protein-like  Recql_predicted  RecQ protein-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Recql_predicted  RecQ protein-like (predicted)      Symbol and Name status set to approved 70820 APPROVED