Gene: Map3k1 (mitogen-activated protein kinase kinase kinase 1) Rattus norvegicus
Analyze
Symbol: Map3k1
Name: mitogen-activated protein kinase kinase kinase 1
Description: ENCODES a protein that exhibits JUN kinase binding; JUN kinase kinase kinase activity; MAP kinase kinase kinase activity; INVOLVED IN activation of JNKK activity; activation of MAPKK activity; MAPK cascade; PARTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; ceramide signaling pathway; ASSOCIATED WITH 46,XY Sex Reversal 6 (ortholog); Breast Neoplasms (ortholog); Microphthalmia, Syndromic 1 (ortholog); FOUND IN cytoplasm; cytoskeleton; membrane; INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1; Mekk1; mitogen activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0243,329,516 - 43,393,203 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0262,373,717 - 62,440,715 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4243,062,252 - 43,126,058 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1242,987,560 - 43,051,968 (-)NCBI
Celera239,134,930 - 39,199,049 (-)NCBI
Cytogenetic Map2q14NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Map3k1
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 620966
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-11-18
Status: ACTIVE