Gene: Lepr (leptin receptor) Rattus norvegicus
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Symbol: Lepr
Name: leptin receptor
Description: ENCODES a protein that exhibits peptide hormone binding; protein-hormone receptor activity; identical protein binding (ortholog); INVOLVED IN aging; angiogenesis; cellular response to organic substance; PARTICIPATES IN leptin system pathway; altered leptin system pathway; obesity disease pathway; ASSOCIATED WITH Hypertrophy, Left Ventricular; Liver Cirrhosis, Experimental; Myocardial Reperfusion Injury; FOUND IN extracellular space; plasma membrane; receptor complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fa; LEP-R; Leptin receptor (fatty); OB receptor; OB-R
Orthologs:
Allele / Splice: Lepr_v2   Lepr_v1   Leprem2Mcwi   Leprm1Rll  
Is Marker For: Strains:   ZUC-LeprfaSte   ZUC-Lepr+Ste   KZ-LeprfaTky   F344.ZUC-Leprfa/Tj   ZDF-LeprfaCrlCrlj   F344.ZUC-(Leprfa),OLETF-(D14Rat23-D14Rat12)/Tj  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05120,503,475 - 120,682,281 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05124,380,327 - 124,525,200 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.05124,555,678 - 124,556,585 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.45122,320,075 - 122,503,449NCBIRGSC3.4rn4RGSC3.4
Celera5114,817,255 - 114,982,861 (+)NCBI
Cytogenetic Map5q33NCBImapview
RH 3.4 Map5 RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lepr
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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RGD Object Information
RGD ID: 3001
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-06
Status: ACTIVE