| (R)-carnitine | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Carnitine | CTD | PMID:20567778 |
| (R)-pantothenic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Pantothenic Acid | CTD | PMID:20567778 |
| (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of LEPR mRNA | CTD | PMID:22265867 |
| 1-methylnicotinamide | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of N(1)-methylnicotinamide | CTD | PMID:20567778 |
| 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:10865 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LEPR mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | increases expression | ISO | RGD:10865 | 6480464 | Ethinyl Estradiol results in increased expression of LEPR mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of LEPR mRNA | CTD | PMID:17351261 |
| 17beta-estradiol | affects abundance | EXP | | 6480464 | LEPR protein affects the abundance of Estradiol | CTD | PMID:15093691 |
| 17beta-estradiol | decreases expression | ISO | RGD:735832 | 6480464 | Estradiol results in decreased expression of LEPR mRNA | CTD | PMID:19167446 |
| 17beta-estradiol | decreases expression | ISO | RGD:10865 | 6480464 | Estradiol results in decreased expression of LEPR mRNA | CTD | PMID:14664709 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:735832 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LEPR mRNA | CTD | PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LEPR mRNA | CTD | PMID:20959002 PMID:21724226 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LEPR mRNA | CTD | PMID:21724226 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:735832 | 6480464 | Tetrachlorodibenzodioxin affects the expression of LEPR mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LEPR mRNA | CTD | PMID:15977195 PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LEPR mRNA | CTD | PMID:15977195 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:10865 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LEPR mRNA | CTD | PMID:17942748 |
| 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of LEPR mRNA | CTD | PMID:21346803 |
| 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of LEPR mRNA | CTD | PMID:21346803 |
| 2-amino-2-deoxy-D-galactopyranose | increases response to substance | ISO | RGD:10865 | 6480464 | LEPR gene mutant form results in increased susceptibility to Galactosamine | CTD | PMID:19913045 |
| 2-amino-2-deoxy-D-galactopyranose | multiple interactions | ISO | RGD:10865 | 6480464 | [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA; more ... | CTD | PMID:19913045 |
| 2-hydroxy-4-methylvaleric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of alpha-hydroxyisocaproic acid | CTD | PMID:20567778 |
| 2-hydroxyisobutyric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of 2-hydroxyisobutyric acid | CTD | PMID:20567778 |
| 2-oxoadipic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of alpha-ketoadipic acid | CTD | PMID:20567778 |
| 2-oxoglutaric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of alpha-ketoglutaric acid | CTD | PMID:20567778 |
| 3-methyl-2-oxobutanoic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of alpha-ketoisovalerate | CTD | PMID:20567778 |
| 3-methyl-2-oxovaleric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of alpha-keto-beta-methylvaleric acid | CTD | PMID:20567778 |
| 4,4'-diaminodiphenylmethane | affects expression | ISO | RGD:10865 | 6480464 | 4,4'-diaminodiphenylmethane affects the expression of LEPR mRNA | CTD | PMID:18648102 |
| acetohydrazide | decreases expression | ISO | RGD:10865 | 6480464 | acetylhydrazine results in decreased expression of LEPR mRNA | CTD | PMID:15282401 |
| acetylcholine | decreases response to substance | ISO | RGD:10865 | 6480464 | LEPR gene mutant form results in decreased susceptibility to Acetylcholine | CTD | PMID:19478208 |
| acetylcholine | multiple interactions | ISO | RGD:10865 | 6480464 | acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; more ... | CTD | PMID:19478208 |
| allantoin | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Allantoin | CTD | PMID:20567778 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of LEPR mRNA | CTD | PMID:16483693 |
| apocynin | multiple interactions | ISO | RGD:10865 | 6480464 | acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; more ... | CTD | PMID:19478208 |
| arsenic atom | decreases expression | ISO | RGD:10865 | 6480464 | Arsenic results in decreased expression of LEPR mRNA | CTD | PMID:19654921 |
| astaxanthin | multiple interactions | ISO | RGD:10865 | 6480464 | astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA]; more ... | CTD | PMID:16964424 |
| benzo[a]pyrene | decreases expression | ISO | RGD:10865 | 6480464 | Benzo(a)pyrene results in decreased expression of LEPR mRNA | CTD | PMID:19770486 |
| benzo[a]pyrene | decreases expression | ISO | RGD:735832 | 6480464 | Benzo(a)pyrene results in decreased expression of LEPR mRNA | CTD | PMID:22316170 |
| benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of LEPR mRNA | CTD | PMID:21839799 |
| bisphenol A | increases expression | ISO | RGD:735832 | 6480464 | bisphenol A results in increased expression of LEPR mRNA; more ... | CTD | PMID:22343039 |
| butyric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Butyric Acid | CTD | PMID:20567778 |
| caffeine | increases expression | EXP | | 6480464 | Caffeine results in increased expression of LEPR mRNA | CTD | PMID:22583948 |
| calcium atom | affects expression | EXP | | 6480464 | Calcium affects the expression of LEPR mRNA | CTD | PMID:15913539 |
| calcium(0) | affects expression | EXP | | 6480464 | Calcium affects the expression of LEPR mRNA | CTD | PMID:15913539 |
| caproic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of hexanoic acid | CTD | PMID:20567778 |
| choline | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Choline | CTD | PMID:20567778 |
| choline | multiple interactions | ISO | RGD:10865 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LEPR mRNA | CTD | PMID:20938992 |
| chromium atom | multiple interactions | ISO | RGD:10865 | 6480464 | LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in decreased expression of BTC mRNA]; more ... | CTD | PMID:16940432 |
| ciguatoxin CTX1B | affects expression | ISO | RGD:10865 | 6480464 | Ciguatoxins affects the expression of LEPR mRNA | CTD | PMID:18353800 |
| citric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Citric Acid | CTD | PMID:20567778 |
| clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of LEPR mRNA | CTD | PMID:22008536 |
| clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of LEPR mRNA | CTD | PMID:17602206 |
| coumestrol | decreases expression | ISO | RGD:735832 | 6480464 | Coumestrol results in decreased expression of LEPR mRNA | CTD | PMID:19167446 |
| coumestrol | multiple interactions | ISO | RGD:735832 | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of LEPR mRNA | CTD | PMID:19167446 |
| creatinine | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Creatinine | CTD | PMID:20567778 |
| cytarabine | decreases expression | ISO | RGD:735832 | 6480464 | Cytarabine results in decreased expression of LEPR mRNA | CTD | PMID:21198554 |
| D-glucose | decreases response to substance | ISO | RGD:10865 | 6480464 | LEPR results in decreased susceptibility to Glucose | CTD | PMID:20567778 |
| D-glucose | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Glucose | CTD | PMID:20567778 |
| diazoxide | increases expression | EXP | | 6480464 | Isoproterenol results in increased expression of LEPR mRNA; more ... | CTD | PMID:20307649 |
| diazoxide | multiple interactions | EXP | | 6480464 | CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA]; more ... | CTD | PMID:20307649 |
| dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of LEPR mRNA | CTD | PMID:21266533 |
| diethyl maleate | decreases expression | EXP | | 6480464 | diethyl maleate results in decreased expression of LEPR mRNA | CTD | PMID:21161181 |
| dobutamine | affects response to substance | ISO | RGD:10865 | 6480464 | LEPR protein affects the susceptibility to Dobutamine | CTD | PMID:20175764 |
| estrone | multiple interactions | ISO | RGD:10865 | 6480464 | Estrone inhibits the reaction [LEPR gene mutant form inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein]]; more ... | CTD | PMID:1753381 |
| ethanol | multiple interactions | EXP | | 6480464 | LEPR gene mutant form inhibits the reaction [Ethanol results in increased expression of MT1A mRNA]; more ... | CTD | PMID:15475485 |
| ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of LEPR mRNA | CTD | PMID:16098508 |
| ethanol | multiple interactions | EXP | | 6480464 | Drugs, Chinese Herbal inhibits the reaction [[Carbon Tetrachloride co-treated with Ethanol] results in increased expression of LEPR protein] | CTD | PMID:18227024 |
| ethanol | increases response to substance | EXP | | 6480464 | LEPR gene mutant form results in increased susceptibility to Ethanol | CTD | PMID:15475485 |
| ethylmalonic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Methylmalonic Acid | CTD | PMID:20567778 |
| folic acid | multiple interactions | ISO | RGD:10865 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LEPR mRNA | CTD | PMID:20938992 |
| formic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of formic acid | CTD | PMID:20567778 |
| fumaric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of fumaric acid | CTD | PMID:20567778 |
| furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of LEPR gene | CTD | PMID:22079235 |
| galactaric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of galactaric acid | CTD | PMID:20567778 |
| gefitinib | decreases expression | ISO | RGD:735832 | 6480464 | gefitinib results in decreased expression of LEPR mRNA | CTD | PMID:16685379 |
| glucose | decreases response to substance | ISO | RGD:10865 | 6480464 | LEPR results in decreased susceptibility to Glucose | CTD | PMID:20567778 |
| glucose | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Glucose | CTD | PMID:20567778 |
| glutaric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of glutaric acid | CTD | PMID:20567778 |
| hydrazine | increases expression | EXP | | 6480464 | hydrazine results in increased expression of LEPR mRNA | CTD | PMID:15370871 |
| indoxyl sulfate | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Indican | CTD | PMID:20567778 |
| isobutyric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of isobutyric acid | CTD | PMID:20567778 |
| isoprenaline | increases expression | EXP | | 6480464 | Isoproterenol results in increased expression of LEPR mRNA; more ... | CTD | PMID:20307649 |
| isoprenaline | multiple interactions | EXP | | 6480464 | CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA]; more ... | CTD | PMID:20307649 |
| isovaleric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of isovaleric acid | CTD | PMID:20567778 |
| L-methionine | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Methionine | CTD | PMID:20567778 |
| L-methionine | multiple interactions | ISO | RGD:10865 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LEPR mRNA | CTD | PMID:20938992 |
| lactic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Lactic Acid | CTD | PMID:20567778 |
| malonic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of malonic acid | CTD | PMID:20567778 |
| mercury atom | decreases expression | ISO | RGD:735832 | 6480464 | Mercury results in decreased expression of LEPR mRNA | CTD | PMID:16823088 |
| mercury(0) | decreases expression | ISO | RGD:735832 | 6480464 | Mercury results in decreased expression of LEPR mRNA | CTD | PMID:16823088 |
| methylmalonic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Methylmalonic Acid | CTD | PMID:20567778 |
| morphine | increases expression | ISO | RGD:10865 | 6480464 | Morphine results in increased expression of LEPR mRNA | CTD | PMID:20144693 |
| N-ethyl-N-nitrosourea | increases mutagenesis | ISO | RGD:10865 | 6480464 | Ethylnitrosourea results in increased mutagenesis of LEPR gene | CTD | PMID:16724327 |
| N-methyl-6-pyridone-3-carboxamide | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of N'-methyl-2-pyridone-5-carboxamide | CTD | PMID:20567778 |
| N-methylnicotinate | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of trigonelline | CTD | PMID:20567778 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LEPR mRNA | CTD | PMID:18164116 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of LEPR mRNA | CTD | PMID:17602206 |
| nicotinic acid | multiple interactions | ISO | RGD:10865 | 6480464 | LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in decreased expression of BTC mRNA]; more ... | CTD | PMID:16940432 |
| orotic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Orotic Acid | CTD | PMID:20567778 |
| ozone | multiple interactions | ISO | RGD:10865 | 6480464 | LEPR gene mutant form promotes the reaction [Ozone results in increased expression of CCL11 protein]; more ... | CTD | PMID:16373670 |
| ozone | increases response to substance | ISO | RGD:10865 | 6480464 | LEPR gene mutant form results in increased susceptibility to Ozone | CTD | PMID:16373670 |
| perfluorooctanoic acid | increases expression | ISO | RGD:10865 | 6480464 | perfluorooctanoic acid results in increased expression of LEPR mRNA | CTD | PMID:17681415 |
| phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of LEPR mRNA | CTD | PMID:22008536 |
| phenobarbital | affects expression | ISO | RGD:10865 | 6480464 | Phenobarbital affects the expression of LEPR mRNA | CTD | PMID:23091169 |
| pirinixic acid | multiple interactions | ISO | RGD:735832 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LEPR mRNA | CTD | PMID:19710929 |
| pirinixic acid | increases expression | ISO | RGD:10865 | 6480464 | pirinixic acid results in increased expression of LEPR mRNA | CTD | PMID:18301758 more ... |
| pirinixic acid | increases expression | ISO | RGD:10865 | 6480464 | pirinixic acid results in increased expression of LEPR mRNA | CTD | PMID:20813756 more ... |
| pirinixic acid | increases expression | ISO | RGD:10865 | 6480464 | pirinixic acid results in increased expression of LEPR mRNA | CTD | PMID:18445702 more ... |
| pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of LEPR mRNA | CTD | PMID:19162173 |
| razoxane | decreases expression | EXP | | 6480464 | Razoxane results in decreased expression of LEPR mRNA | CTD | PMID:19915844 |
| resveratrol | multiple interactions | ISO | RGD:10865 | 6480464 | resveratrol inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; more ... | CTD | PMID:19478208 |
| riddelliine | increases expression | EXP | | 6480464 | riddelliine results in increased expression of LEPR mRNA | CTD | PMID:18047727 |
| simvastatin | affects response to substance | ISO | RGD:735832 | 6480464 | LEPR polymorphism affects the susceptibility to Simvastatin | CTD | PMID:18854995 PMID:14625131 |
| simvastatin | affects response to substance | ISO | RGD:735832 | 6480464 | LEPR polymorphism affects the susceptibility to Simvastatin | CTD | PMID:14625131 PMID:18854995 |
| succinic acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Succinic Acid | CTD | PMID:20567778 |
| sucrose | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Sucrose | CTD | PMID:20567778 |
| superoxide | multiple interactions | ISO | RGD:10865 | 6480464 | resveratrol inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides]; more ... | CTD | PMID:19478208 |
| superoxide | increases abundance | ISO | RGD:10865 | 6480464 | LEPR gene mutant form results in increased abundance of Superoxides | CTD | PMID:19478208 |
| tacrine | increases expression | EXP | | 6480464 | Tacrine results in increased expression of LEPR mRNA | CTD | PMID:12832660 |
| taurine | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of Taurine | CTD | PMID:20567778 |
| testosterone | affects abundance | EXP | | 6480464 | LEPR protein affects the abundance of Testosterone | CTD | PMID:15093691 |
| tetrachloromethane | multiple interactions | EXP | | 6480464 | Drugs, Chinese Herbal inhibits the reaction [[Carbon Tetrachloride co-treated with Ethanol] results in increased expression of LEPR protein] | CTD | PMID:18227024 |
| thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of LEPR mRNA; more ... | CTD | PMID:17621560 |
| thioacetamide | multiple interactions | EXP | | 6480464 | Lipopolysaccharides inhibits the reaction [Thioacetamide results in decreased expression of LEPR mRNA] | CTD | PMID:17621560 |
| thioacetamide | multiple interactions | EXP | | 6480464 | LEPR gene mutant form inhibits the reaction [Thioacetamide results in increased expression of TGFB1 mRNA]; more ... | CTD | PMID:11984526 |
| topotecan | affects response to substance | ISO | RGD:735832 | 6480464 | LEPR protein affects the susceptibility to Topotecan | CTD | PMID:16217747 |
| trans-resveratrol | multiple interactions | ISO | RGD:10865 | 6480464 | resveratrol inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]; more ... | CTD | PMID:19478208 |
| trimellitic anhydride | decreases expression | ISO | RGD:10865 | 6480464 | trimellitic anhydride results in decreased expression of LEPR mRNA | CTD | PMID:19042947 |
| valeric acid | affects abundance | ISO | RGD:10865 | 6480464 | LEPR affects the abundance of n-pentanoic acid | CTD | PMID:20567778 |
| zinc atom | multiple interactions | EXP | | 6480464 | [LEPR gene mutant form results in increased susceptibility to Ethanol] which results in decreased abundance of Zinc | CTD | PMID:15475485 |
| zinc(0) | multiple interactions | EXP | | 6480464 | [LEPR gene mutant form results in increased susceptibility to Ethanol] which results in decreased abundance of Zinc | CTD | PMID:15475485 |