Gene: Park2 (parkinson protein 2, E3 ubiquitin protein ligase) Rattus norvegicus
Symbol: Park2
Name: parkinson protein 2, E3 ubiquitin protein ligase
Description: ENCODES a protein that exhibits protein complex binding; chaperone binding (ortholog); cullin family protein binding (ortholog); INVOLVED IN negative regulation of neuron death; negative regulation of oxidative stress-induced neuron death; neuron maturation; PARTICIPATES IN altered ubiquitin/proteasome degradation pathway; Parkinson disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Adenocarcinoma of lung (ortholog); Carcinoma, Non-Small-Cell Lung (ortholog); Leprosy (ortholog); FOUND IN cytoplasm; cytoplasmic vesicle; endoplasmic reticulum; INTERACTS WITH ammonium chloride; Aroclor 1254; C60 fullerene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase parkin; Park; parkin; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Prkn
Orthologs:
Allele / Splice: Park2em1Sage  
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.0148,880,015 - 50,069,998-NCBI
Rat Cytogenetic Map1q11 NCBI
RGSC Genome Assembly v5.0149,684,308 - 50,875,397+NCBI
RGSC Genome Assembly v3.4143,151,265 - 44,374,470-NCBI
Rat Celera Assembly144,478,407 - 45,666,902-NCBI
Genome Assembly 3.1143,154,209 - 44,377,415-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Park2
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 61797
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2014-11-11
Status: ACTIVE