Gene: Park2 (parkin RBR E3 ubiquitin protein ligase) Rattus norvegicus
Symbol: Park2
Name: parkin RBR E3 ubiquitin protein ligase
Description: ENCODES a protein that exhibits protein complex binding; actin binding (ortholog); chaperone binding (ortholog); INVOLVED IN mitochondrion degradation; mitochondrion localization; negative regulation of neuron death; PARTICIPATES IN altered ubiquitin/proteasome degradation pathway; Parkinson disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Adenocarcinoma of lung (ortholog); Leprosy (ortholog); Lung Neoplasms (ortholog); FOUND IN cytoplasm; cytoplasmic vesicle; endoplasmic reticulum; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; Aroclor 1254
Type: protein-coding
Also known as: E3 ubiquitin-protein ligase parkin; Park; parkin; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson protein 2, E3 ubiquitin protein ligase; Prkn
Allele / Splice: Park2em1Sage  
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.0148,880,015 - 50,069,998-NCBI
Rat Cytogenetic Map1q11 NCBI
RGSC Genome Assembly v5.0149,684,308 - 50,875,397+NCBI
RGSC Genome Assembly v3.4143,151,265 - 44,374,470-NCBI
Rat Celera Assembly144,478,407 - 45,666,902-NCBI
Genome Assembly 3.1143,154,209 - 44,377,415-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Park2
Entrez Gene
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RGD Object Information
RGD ID: 61797
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE