Gene: Nrg1 (neuregulin 1)  Rattus norvegicus

Symbol: Nrg1
Name: neuregulin 1
Description: ENCODES a protein that exhibits ErbB-3 class receptor binding; ErbB-2 class receptor binding (ortholog); growth factor activity (ortholog); INVOLVED IN glucose transport; myelination; regulation of blood pressure; PARTICIPATES IN angiotensin II signaling pathway; epidermal growth factor/neuregulin signaling pathway; glypican signaling pathway; FOUND IN apical plasma membrane (ortholog); axon (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neuregulin 1; neuregulin 1 type III beta 3; pro-neuregulin-1, membrane-bound isoform; pro-NRG1
Orthologs: Homo sapiens : NRG1 (neuregulin 1)  HGNC
Mus musculus : Nrg1 (neuregulin 1)  MGI
Allele / Splice: Nrg1Tn(sb-T2/Bart3)2.183Mcwi  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map16q12.3 NCBI
RGSC Genome Assembly v5.01663,540,649 - 63,718,738+NCBI
RGSC Genome Assembly v3.41663,937,796 - 64,126,183+NCBI
Rat Celera Assembly1658,125,632 - 58,311,856+NCBI
Genome Assembly 3.11663,937,870 - 64,126,262+NCBI
Model

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Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nrg1
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Ensembl Gene
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RGD Object Information
RGD ID: 621341
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE