Gene: Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2)  Rattus norvegicus
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Description: ENCODES a protein that exhibits monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; caffeine oxidase activity (ortholog); INVOLVED IN response to drug; response to estradiol stimulus; response to lipopolysaccharide; PARTICIPATES IN caffeine metabolic pathway; linoleic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH Depressive Disorder; Jaundice; Sepsis; FOUND IN intracellular membrane-bounded organelle; INTERACTS WITH (+)-alpha-tocopherol; (+)-artemisinin; (-)-epigallocatechin 3-gallate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CYPD45; CYPIA2; cytochrome P-448; cytochrome P-450d; cytochrome P450 1A2; Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450, 1a2; Cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450-D; P-448; P-450d; P450-D; RATCYPD45
Orthologs: Homo sapiens : CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2)  HGNC
Mus musculus : Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map8q24 NCBI
RGSC Genome Assembly v5.0862,228,271 - 62,235,203-NCBI
RGSC Genome Assembly v3.4861,439,062 - 61,447,861-NCBI
Rat Celera Assembly857,541,217 - 57,547,956-NCBI
Genome Assembly 3.1861,458,143 - 61,464,586-NCBI
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