Gene: Aldh2 (aldehyde dehydrogenase 2 family (mitochondrial)) Rattus norvegicus
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Symbol: Aldh2
Name: aldehyde dehydrogenase 2 family (mitochondrial)
Description: ENCODES a protein that exhibits aldehyde dehydrogenase (NAD) activity; identical protein binding; NADH binding; INVOLVED IN cellular response to fatty acid; cellular response to hormone stimulus; liver development; PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH alcohol preference; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; Fatty Liver, Alcoholic; heart disease; FOUND IN mitochondrion; extracellular exosome (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aldehyde dehydrogenase 2; aldehyde dehydrogenase 2 mitochondrial; aldehyde dehydrogenase 2, mitochondrial; aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDH1; mitochondrial aldehyde dehydrogenase
Orthologs:
Homo sapiens (human) : ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial))  HGNC  AGR
Mus musculus (house mouse) : Aldh2 (aldehyde dehydrogenase 2, mitochondrial)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Aldh2 (aldehyde dehydrogenase 2 family (mitochondrial))
Pan paniscus (bonobo/pygmy chimpanzee) : ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial))
Canis lupus familiaris (dog) : ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldh2 (aldehyde dehydrogenase 2 family (mitochondrial))
more info ...
Allele / Splice: Aldh2em2Mcwi  
Genetic Models: SS-Aldh2em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01240,466,418 - 40,498,813 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01242,334,057 - 42,366,049 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41236,081,778 - 36,116,445 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,945,165 - 35,979,833 (+)NCBI
Celera1236,614,188 - 36,647,218 (+)NCBI
Cytogenetic Map12q16NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Aldh2
AGR Gene
NCBI Gene
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RGD Object Information
RGD ID: 69219
Created: 2001-11-13
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE