Gene: Epas1 (endothelial PAS domain protein 1) Rattus norvegicus
Symbol: Epas1
Name: endothelial PAS domain protein 1
Description: ENCODES a protein that exhibits cobalt ion binding; sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding; INVOLVED IN negative regulation of transcription from RNA polymerase II promoter; positive regulation of lung alveolus development; positive regulation of transcription from RNA polymerase II promoter; PARTICIPATES IN hypoxia inducible factor pathway; renal cell cancer pathway; ASSOCIATED WITH Acute Kidney Injury; Brain Injuries; Bronchopulmonary Dysplasia; FOUND IN cytoplasm; nucleus; nuclear speck (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 1H-benzimidazole; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: endothelial PAS domain-containing protein 1; EPAS-1; HIF-2 alpha; HIF-2-alpha; HIF2 alpha; HIF2-alpha; Hif2a; HLF; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0610,306,508 - 10,385,239+NCBI
Rat Cytogenetic Map6q12 NCBI
RGSC Genome Assembly v5.0620,299,603 - 20,379,864+NCBI
RGSC Genome Assembly v3.4610,203,108 - 10,297,215+NCBI
Rat Celera Assembly67,526,511 - 7,605,382-NCBI
Genome Assembly 3.1610,203,107 - 10,297,215+NCBI

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QTLs in Region (RGSC Genome Assembly v5.0)
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Nucleotide Sequences
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Strain Variation

Strain Sequence Variants

Additional Information

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Nomenclature History
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More on Epas1
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RGD Object Information
RGD ID: 68404
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2015-11-10
Status: ACTIVE