Gene: Epas1 (endothelial PAS domain protein 1) Rattus norvegicus
Analyze
Symbol: Epas1
Name: endothelial PAS domain protein 1
Description: ENCODES a protein that exhibits cobalt ion binding; sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding; INVOLVED IN cellular response to hypoxia; cellular response to interleukin-1; cellular response to lipopolysaccharide; PARTICIPATES IN hypoxia inducible factor pathway; renal cell cancer pathway; ASSOCIATED WITH acute kidney failure; Acute Kidney Injury; acute myocardial infarction; FOUND IN cytoplasm; nucleus; nuclear speck (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 1H-benzimidazole; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endothelial PAS domain-containing protein 1; EPAS-1; HIF-2 alpha; HIF-2-alpha; HIF2 alpha; HIF2-alpha; Hif2a; HLF; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha
Orthologs:
Homo sapiens (human) : EPAS1 (endothelial PAS domain protein 1)  HGNC
Mus musculus (house mouse) : Epas1 (endothelial PAS domain protein 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Epas1 (endothelial PAS domain protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPAS1 (endothelial PAS domain protein 1)
Canis lupus familiaris (dog) : EPAS1 (endothelial PAS domain protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epas1 (endothelial PAS domain protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0610,306,508 - 10,385,239 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0620,299,603 - 20,379,864 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4610,203,108 - 10,297,215 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1610,203,107 - 10,297,215 (+)NCBI
Celera67,526,511 - 7,605,382 (-)NCBI
Cytogenetic Map6q12NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Epas1
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 68404
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2017-07-11
Status: ACTIVE