| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | RGD:68595 | 6480464 | [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EPAS1 mRNA | CTD | PMID:19679656 |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of EPAS1 mRNA | CTD | PMID:17351261 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:68595 | 6480464 | Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA | CTD | PMID:16962184 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:68595 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EPAS1 mRNA | CTD | PMID:19933214 |
| 2-amino-2-deoxy-D-glucopyranose | decreases expression | EXP | | 6480464 | Glucosamine results in decreased expression of EPAS1 mRNA | CTD | PMID:17109745 |
| 2-amino-2-deoxy-D-glucopyranose | multiple interactions | EXP | | 6480464 | Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; more ... | CTD | PMID:17109745 |
| 2-methylcholine | affects expression | ISO | RGD:68594 | 6480464 | beta-methylcholine affects the expression of EPAS1 mRNA | CTD | PMID:21179406 |
| 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:68595 | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of EPAS1 mRNA | CTD | PMID:18648102 |
| 4-hydroperoxycyclophosphamide | increases expression | ISO | RGD:68595 | 6480464 | perfosfamide results in increased expression of EPAS1 protein | CTD | PMID:23251655 |
| 5-fluorouracil | increases expression | ISO | RGD:68594 | 6480464 | Fluorouracil results in increased expression of EPAS1 mRNA | CTD | PMID:16557594 |
| aldehydo-D-glucosamine | decreases expression | EXP | | 6480464 | Glucosamine results in decreased expression of EPAS1 mRNA | CTD | PMID:17109745 |
| aldehydo-D-glucosamine | multiple interactions | EXP | | 6480464 | Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; more ... | CTD | PMID:17109745 |
| all-trans-retinoic acid | increases expression | ISO | RGD:68594 | 6480464 | Tretinoin results in increased expression of EPAS1 mRNA | CTD | PMID:17138961 |
| all-trans-retinoic acid | increases expression | ISO | RGD:68594 | 6480464 | Tretinoin results in increased expression of EPAS1 mRNA | CTD | PMID:15894607 more ... |
| all-trans-retinoic acid | increases expression | ISO | RGD:68594 | 6480464 | Tretinoin results in increased expression of EPAS1 mRNA | CTD | PMID:17138961 PMID:21934132 |
| all-trans-retinoic acid | increases expression | ISO | RGD:68594 | 6480464 | Tretinoin results in increased expression of EPAS1 mRNA | CTD | PMID:21934132 PMID:17138961 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of EPAS1 mRNA | CTD | PMID:16483693 |
| antimycin A | multiple interactions | EXP | | 6480464 | Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] | CTD | PMID:18353899 |
| aristolochic acid | increases expression | ISO | RGD:68594 | 6480464 | aristolochic acid I results in increased expression of EPAS1 protein | CTD | PMID:21554934 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:68595 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of EPAS1 mRNA | CTD | PMID:21715664 |
| benzo[a]pyrene | increases expression | ISO | RGD:68595 | 6480464 | Benzo(a)pyrene results in increased expression of EPAS1 mRNA | CTD | PMID:22228805 |
| benzo[a]pyrene | decreases expression | ISO | RGD:68595 | 6480464 | Benzo(a)pyrene results in decreased expression of EPAS1 mRNA | CTD | PMID:19770486 PMID:22228805 |
| benzo[a]pyrene | decreases expression | ISO | RGD:68595 | 6480464 | Benzo(a)pyrene results in decreased expression of EPAS1 mRNA | CTD | PMID:19770486 |
| beta-D-glucosamine | decreases expression | EXP | | 6480464 | Glucosamine results in decreased expression of EPAS1 mRNA | CTD | PMID:17109745 |
| beta-D-glucosamine | multiple interactions | EXP | | 6480464 | Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; more ... | CTD | PMID:17109745 |
| bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:68595 | 6480464 | Mustard Gas results in increased expression of EPAS1 mRNA | CTD | PMID:15674843 |
| cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of EPAS1 promoter | CTD | PMID:22457795 |
| chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of EPAS1 mRNA | CTD | PMID:18668222 |
| choline | multiple interactions | ISO | RGD:68595 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA; more ... | CTD | PMID:20938992 |
| ciglitazone | multiple interactions | ISO | RGD:68594 | 6480464 | [ciglitazone binds to PPARG protein] which results in increased expression of EPAS1 mRNA | CTD | PMID:16197558 |
| cobalt atom | increases expression | EXP | | 6480464 | Cobalt results in increased expression of EPAS1 protein | CTD | PMID:17967803 |
| cobalt dichloride | increases stability | ISO | RGD:68594 | 6480464 | cobaltous chloride results in increased stability of EPAS1 protein | CTD | PMID:18515279 |
| copper(2+) sulfate | increases expression | ISO | RGD:68594 | 6480464 | Copper Sulfate results in increased expression of EPAS1 mRNA | CTD | PMID:19549813 |
| crocidolite asbestos | increases expression | ISO | RGD:68594 | 6480464 | Asbestos, Crocidolite results in increased expression of EPAS1 mRNA | CTD | PMID:18687144 |
| cyclosporin A | decreases expression | ISO | RGD:68594 | 6480464 | Cyclosporine results in decreased expression of EPAS1 mRNA | CTD | PMID:20106945 |
| cyclosporin A | decreases expression | ISO | RGD:68595 | 6480464 | Cyclosporine results in decreased expression of EPAS1 mRNA | CTD | PMID:19770486 |
| dasatinib (anhydrous) | increases expression | ISO | RGD:68594 | 6480464 | dasatinib results in increased expression of EPAS1 mRNA | CTD | PMID:20579391 |
| delphinidin | multiple interactions | ISO | RGD:68594 | 6480464 | delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] | CTD | PMID:18603805 |
| desferrioxamine B | increases expression | EXP | | 6480464 | Deferoxamine results in increased expression of EPAS1 protein | CTD | PMID:18353899 |
| desferrioxamine B | increases stability | ISO | RGD:68594 | 6480464 | Deferoxamine results in increased stability of EPAS1 protein | CTD | PMID:18515279 |
| desferrioxamine B | multiple interactions | ISO | RGD:68594 | 6480464 | Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] | CTD | PMID:18515279 |
| diclofenac | decreases expression | ISO | RGD:68594 | 6480464 | Diclofenac results in decreased expression of EPAS1 protein | CTD | PMID:12912967 |
| dioxygen | multiple interactions | ISO | RGD:68594 | 6480464 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] | CTD | PMID:21994956 |
| dioxygen | increases expression | ISO | RGD:68594 | 6480464 | Oxygen deficiency results in increased expression of EPAS1 mRNA | CTD | PMID:20862257 |
| dioxygen | multiple interactions | ISO | RGD:68595 | 6480464 | Oxygen deficiency affects the localization of and results in increased activity of EPAS1 protein | CTD | PMID:20880076 |
| dioxygen | affects response to substance | EXP | | 6480464 | EPAS1 protein affects the susceptibility to Oxygen deficiency | CTD | PMID:12679337 |
| dioxygen | multiple interactions | EXP | | 6480464 | EPAS1 protein affects the reaction [Oxygen deficiency results in increased expression of CACNA1H mRNA] | CTD | PMID:12679337 |
| dioxygen | multiple interactions | ISO | RGD:68594 | 6480464 | [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [Oxygen deficiency results in decreased expression of USP28 protein]; more ... | CTD | PMID:20046830 |
| dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of EPAS1 protein | CTD | PMID:18353899 |
| dioxygen | multiple interactions | EXP | | 6480464 | COX10 protein affects the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]; more ... | CTD | PMID:18353899 |
| dioxygen | increases expression | ISO | RGD:68594 | 6480464 | Oxygen deficiency results in increased expression of EPAS1 protein | CTD | PMID:21994956 |
| folic acid | multiple interactions | ISO | RGD:68595 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene; more ... | CTD | PMID:20938992 |
| galangin | multiple interactions | ISO | RGD:68594 | 6480464 | ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein]; more ... | CTD | PMID:17973296 |
| galangin | increases expression | ISO | RGD:68594 | 6480464 | galangin results in increased expression of EPAS1 protein | CTD | PMID:17973296 |
| hydralazine | multiple interactions | ISO | RGD:68594 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA | CTD | PMID:17183730 |
| hydrogen peroxide | multiple interactions | ISO | RGD:68594 | 6480464 | delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] | CTD | PMID:18603805 |
| hydrogen peroxide | increases expression | ISO | RGD:68594 | 6480464 | Hydrogen Peroxide results in increased expression of EPAS1 protein | CTD | PMID:18603805 |
| hydrogen peroxide | affects expression | ISO | RGD:68594 | 6480464 | Hydrogen Peroxide affects the expression of EPAS1 mRNA | CTD | PMID:20044591 |
| ibuprofen | decreases expression | ISO | RGD:68594 | 6480464 | Ibuprofen results in decreased expression of EPAS1 protein | CTD | PMID:12912967 |
| iron atom | multiple interactions | ISO | RGD:68594 | 6480464 | Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein]; more ... | CTD | PMID:17973296 |
| L-ascorbic acid | multiple interactions | ISO | RGD:68594 | 6480464 | Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] | CTD | PMID:16288478 |
| L-methionine | multiple interactions | ISO | RGD:68595 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene; more ... | CTD | PMID:20938992 |
| manganese(II) chloride | increases expression | ISO | RGD:68595 | 6480464 | manganese chloride results in increased expression of EPAS1 mRNA | CTD | PMID:17467022 |
| menadione | affects expression | ISO | RGD:68594 | 6480464 | Vitamin K 3 affects the expression of EPAS1 mRNA | CTD | PMID:20044591 |
| methotrexate | increases expression | ISO | RGD:68594 | 6480464 | Methotrexate results in increased expression of EPAS1 mRNA | CTD | PMID:17400583 |
| myxothiazol | multiple interactions | EXP | | 6480464 | myxothiazol inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] | CTD | PMID:18353899 |
| nickel sulfate | increases stability | ISO | RGD:68594 | 6480464 | nickel sulfate results in increased stability of EPAS1 protein | CTD | PMID:20046830 |
| nickel sulfate | multiple interactions | ISO | RGD:68594 | 6480464 | Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] | CTD | PMID:16288478 |
| nickel sulfate | multiple interactions | ISO | RGD:68594 | 6480464 | [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]; more ... | CTD | PMID:20046830 |
| nickel sulfate | increases expression | ISO | RGD:68594 | 6480464 | nickel sulfate results in increased expression of EPAS1 protein | CTD | PMID:16288478 |
| ochratoxin A | multiple interactions | ISO | RGD:68594 | 6480464 | EPAS1 protein inhibits the reaction [ochratoxin A results in decreased expression of VEGFA protein] | CTD | PMID:21554934 |
| ochratoxin A | decreases expression | ISO | RGD:68594 | 6480464 | ochratoxin A results in decreased expression of EPAS1 protein | CTD | PMID:21554934 |
| phenylephrine | decreases expression | EXP | | 6480464 | Phenylephrine results in decreased expression of EPAS1 mRNA | CTD | PMID:18158353 |
| pirinixic acid | increases expression | ISO | RGD:68595 | 6480464 | pirinixic acid results in increased expression of EPAS1 mRNA | CTD | PMID:17426115 PMID:18301758 |
| pirinixic acid | increases expression | ISO | RGD:68595 | 6480464 | pirinixic acid results in increased expression of EPAS1 mRNA | CTD | PMID:18301758 PMID:17426115 |
| piroxicam | decreases expression | ISO | RGD:68594 | 6480464 | Piroxicam results in decreased expression of EPAS1 mRNA | CTD | PMID:21858171 |
| quercetin | multiple interactions | ISO | RGD:68594 | 6480464 | Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]; more ... | CTD | PMID:17973296 |
| quercetin | increases expression | ISO | RGD:68594 | 6480464 | Quercetin results in increased expression of EPAS1 protein | CTD | PMID:17973296 |
| rifampicin | multiple interactions | ISO | RGD:68594 | 6480464 | [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA | CTD | PMID:21127053 |
| rotenone | multiple interactions | EXP | | 6480464 | Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] | CTD | PMID:18353899 |
| sodium cyanide | multiple interactions | EXP | | 6480464 | Sodium Cyanide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] | CTD | PMID:18353899 |
| trichloroethene | decreases expression | ISO | RGD:68595 | 6480464 | Trichloroethylene results in decreased expression of EPAS1 mRNA | CTD | PMID:19448997 |
| trichloroethene | increases expression | ISO | RGD:68595 | 6480464 | Trichloroethylene results in increased expression of EPAS1 mRNA | CTD | PMID:15363585 |
| valproic acid | multiple interactions | ISO | RGD:68594 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA | CTD | PMID:17183730 |
| valproic acid | affects expression | ISO | RGD:68595 | 6480464 | Valproic Acid affects the expression of EPAS1 mRNA | CTD | PMID:17292431 |