Gene: Epas1 (endothelial PAS domain protein 1) Rattus norvegicus
Symbol: Epas1
Name: endothelial PAS domain protein 1
Description: ENCODES a protein that exhibits sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; DNA binding (ortholog); INVOLVED IN positive regulation of transcription from RNA polymerase II promoter; response to hypoxia; angiogenesis (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; renal cell cancer pathway; ASSOCIATED WITH Myocardial Ischemia; Cardiomegaly (ortholog); Erythrocytosis, Familial, 4 (ortholog); FOUND IN cytoplasm; nucleus; transcription factor complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endothelial PAS domain-containing protein 1; EPAS-1; HIF-2 alpha; HIF-2-alpha; HIF2 alpha; HIF2-alpha; Hif2a; HLF; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.0610,306,508 - 10,385,239+NCBI
Rat Cytogenetic Map6q12 NCBI
RGSC Genome Assembly v5.0620,299,603 - 20,379,864+NCBI
RGSC Genome Assembly v3.4610,203,108 - 10,297,215+NCBI
Rat Celera Assembly67,526,511 - 7,605,382-NCBI
Genome Assembly 3.1610,203,107 - 10,297,215+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Epas1
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 68404
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2014-10-21
Status: ACTIVE