Gene: Acsl4 (acyl-CoA synthetase long-chain family member 4) Rattus norvegicus
Symbol: Acsl4
Name: acyl-CoA synthetase long-chain family member 4
Description: ENCODES a protein that exhibits long-chain fatty acid-CoA ligase activity; arachidonate-CoA ligase activity (ortholog); very long-chain fatty acid-CoA ligase activity (ortholog); INVOLVED IN dendritic spine development; fatty acid transport; response to interleukin-15; PARTICIPATES IN fatty acid beta degradation pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; fatty acid metabolic pathway; ASSOCIATED WITH Arthritis, Experimental (ortholog); Carcinoma, Hepatocellular (ortholog); Depressive Disorder (ortholog); FOUND IN endoplasmic reticulum; mitochondrial membrane; neuronal cell body; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: Acs4; Facl4; fatty acid Coenzyme A ligase, long chain 4; fatty acid-Coenzyme A ligase long chain 4; fatty acid-Coenzyme A ligase, long chain 4; LACS 4; long-chain acyl-CoA synthetase 4; long-chain-fatty-acid--CoA ligase 4
Homo sapiens (human) : ACSL4 (acyl-CoA synthetase long chain family member 4)  HGNC  AGR
Mus musculus (house mouse) : Acsl4 (acyl-CoA synthetase long-chain family member 4)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Acsl4 (acyl-CoA synthetase long chain family member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ACSL4 (acyl-CoA synthetase long chain family member 4)
Canis lupus familiaris (dog) : ACSL4 (acyl-CoA synthetase long chain family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acsl4 (acyl-CoA synthetase long chain family member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X113,596,247 - 113,660,024 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X112,046,187 - 112,109,974 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X36,168,547 - 36,232,162 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X36,222,015 - 36,285,631 (+)NCBI
CeleraX105,356,949 - 105,420,560 (-)NCBICelera
Cytogenetic MapXq33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acsl4
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69401
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE