Gene: Ace (angiotensin I converting enzyme) Rattus norvegicus
Symbol: Ace
Name: angiotensin I converting enzyme
Description: ENCODES a protein that exhibits drug binding; metallopeptidase activity; peptidyl-dipeptidase activity; INVOLVED IN aging; angiogenesis involved in coronary vascular morphogenesis; bradykinin catabolic process; PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angiotensin cascade pathway; angiotensin II signaling pathway; ASSOCIATED WITH decreased angiotensin I-converting enzyme activity; increased angiotensin I-converting enzyme activity; ASSOCIATED WITH Acute Kidney Injury; Alzheimer Disease; Arthritis, Experimental; FOUND IN basal plasma membrane; brush border membrane; extracellular space; INTERACTS WITH (S)-colchicine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: angiotensin 1 converting enzyme; angiotensin 1 converting enzyme 1; angiotensin converting enzyme; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); angiotensin-converting enzyme; Dcp1; Dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); dipeptidyl carboxypeptidase I; kininase II; StsRR92
Allele / Splice: Aceem1Mcwi   Aceem2Mcwi  
Is Marker For: QTLs:   Bp9   Bw57   Bp342   Bw102  
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.01094,170,766 - 94,213,831+NCBI
Rat Cytogenetic Map10q32.1 NCBI
RGSC Genome Assembly v5.01093,922,062 - 93,965,127+NCBI
RGSC Genome Assembly v3.41095,361,338 - 95,381,455+NCBI
Rat Celera Assembly1089,588,544 - 89,608,666+NCBI
Genome Assembly 3.11095,375,707 - 95,395,825+NCBI

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RGD Object Information
RGD ID: 2493
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-03-18
Status: ACTIVE