Gene: Ptk2 (protein tyrosine kinase 2)  Rattus norvegicus

Symbol: Ptk2
Name: protein tyrosine kinase 2
Description: ENCODES a protein that exhibits integrin binding; phosphatidylinositol 3-kinase binding; protein complex binding; INVOLVED IN cellular chloride ion homeostasis; fat cell differentiation; JNK cascade; PARTICIPATES IN long term potentiation; integrin mediated signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; Hypertension; Hypertrophy, Left Ventricular; FOUND IN apical plasma membrane; basolateral plasma membrane; focal adhesion; INTERACTS WITH 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FADK 1; FAK; focal adhesion kinase; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; Protein tyrosine kinase; protein-tyrosine kinase 2; PTK2 protein tyrosine kinase 2
Orthologs: Homo sapiens : PTK2 (protein tyrosine kinase 2)  HGNC
Mus musculus : Ptk2 (PTK2 protein tyrosine kinase 2)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map7q34 NCBI
RGSC Genome Assembly v5.07114,371,992 - 114,525,553-NCBI
RGSC Genome Assembly v3.47110,933,298 - 111,084,554-NCBI
Rat Celera Assembly7101,534,970 - 101,690,471-NCBI
Genome Assembly 3.17110,967,527 - 111,118,784-NCBI
RH 3.47725.6 RGD
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ptk2
Entrez Gene
Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 3443
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-23
Status: ACTIVE