Gpc3 (glypican 3) - Rat Genome Database

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Keyword

Gene: Gpc3 (glypican 3) Rattus norvegicus

Symbol:

Gpc3

Name:

glypican 3

Description:

ENCODES a protein that exhibits peptidyl-dipeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of canonical Wnt receptor signaling pathway; positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; anterior/posterior axis specification (ortholog); PARTICIPATES IN glypican signaling pathway; Hedgehog signaling pathway; ASSOCIATED WITH Heart Defects, Congenital (ortholog); Muscle Hypotonia (ortholog); SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1 (ortholog); FOUND IN anchored to plasma membrane (ortholog); lysosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

defective in Simpson-Golabi-Behmel overgrowth syndrome; glypican 3; glypican-3; intestinal protein OCI-5; MGC93606; OCI-5; proteoglycan GPC3

Orthologs:

Homo sapiens : GPC3 (glypican 3) HGNC
Mus musculus : Gpc3 (glypican 3) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	X	q36		NCBI
RGSC Genome Assembly v5.0	X	139,625,383 - 139,993,328	-	NCBI
RGSC Genome Assembly v3.4	X	139,192,115 - 139,560,649	-	NCBI
Rat Celera Assembly	X	130,783,069 - 131,149,772	-	NCBI
Genome Assembly 3.1	X	139,264,617 - 139,634,082	-	NCBI