Gene: Pten (phosphatase and tensin homolog) Rattus norvegicus
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Symbol: Pten
Name: phosphatase and tensin homolog
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding; PDZ domain binding; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; INVOLVED IN aging; cellular response to ethanol; cellular response to insulin stimulus; PARTICIPATES IN altered phosphatidylinositol 3-kinase signaling pathway; altered phosphatidylinositol 3-kinase-Akt signaling pathway; endometrial cancer pathway; ASSOCIATED WITH alcohol-related neurodevelopmental disorder; Carcinoma, Renal Cell; Cardiomegaly; FOUND IN cytoplasm; cytosol; dendritic spine; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-nicotine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Mmac; MMAC1; mutated in multiple advanced cancers 1; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; TEP1
Orthologs:
Homo sapiens (human) : PTEN (phosphatase and tensin homolog)  HGNC  AGR
Mus musculus (house mouse) : Pten (phosphatase and tensin homolog)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pten (phosphatase and tensin homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : PTEN (phosphatase and tensin homolog)
Canis lupus familiaris (dog) : PTEN (phosphatase and tensin homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pten (phosphatase and tensin homolog)
more info ...
Allele / Splice: Ptenem1Sage  
Genetic Models: SD-Ptenem1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01251,421,814 - 251,487,634 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01258,651,829 - 258,717,009 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41236,771,027 - 236,837,261 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,935,049 - 237,001,284 (+)NCBI
Celera1227,746,622 - 227,812,108 (+)NCBI
Cytogenetic Map1q52NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants