Pten (phosphatase and tensin homolog)

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Keyword

Gene: Pten (phosphatase and tensin homolog) Rattus norvegicus

Symbol:

Pten

Name:

phosphatase and tensin homolog

Description:

ENCODES a protein that exhibits PDZ domain binding; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; platelet-derived growth factor receptor binding; INVOLVED IN aging; long term synaptic depression; memory; PARTICIPATES IN altered phosphatidylinositol 3-kinase-Akt signaling pathway; endometrial cancer pathway; non-small cell lung cancer pathway; ASSOCIATED WITH Cardiomegaly; Diabetes Mellitus; Diabetic Nephropathies; FOUND IN cytoplasm; dendritic spine; mitochondrion; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; 17beta-estradiol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Mmac; MMAC1; mutated in multiple advanced cancers 1; phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; TEP1

Orthologs:

Homo sapiens : PTEN (phosphatase and tensin homolog) HGNC
Mus musculus : Pten (phosphatase and tensin homolog) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	1	q41-q43		NCBI
RGSC Genome Assembly v5.0	1	258,651,829 - 258,717,009	+	NCBI
RGSC Genome Assembly v3.4	1	236,771,027 - 236,837,261	+	NCBI
Rat Celera Assembly	1	227,746,622 - 227,812,108	+	NCBI
Genome Assembly 3.1	1	236,935,049 - 237,001,284	+	NCBI