| (S)-nicotine | multiple interactions | ISO | RGD:1558600 | 6480464 | Nicotine affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of ERN1 mRNA]; more ... | CTD | PMID:20230807 |
| 1,4-dithiothreitol | multiple interactions | EXP | | 6480464 | Dithiothreitol results in increased phosphorylation of and results in increased activity of ERN1 protein | CTD | PMID:12486162 |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | RGD:1558600 | 6480464 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of ERN1 mRNA | CTD | PMID:20230807 |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | RGD:1558600 | 6480464 | Caffeine promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of ERN1 mRNA]; more ... | CTD | PMID:20230807 |
| 17beta-estradiol | increases expression | ISO | RGD:1605125 | 6480464 | Estradiol results in increased expression of ERN1 mRNA | CTD | PMID:23373633 |
| 1H-pyrazole | increases expression | ISO | RGD:1558600 | 6480464 | pyrazole results in increased expression of ERN1 mRNA | CTD | PMID:17945193 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1558600 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ERN1 mRNA | CTD | PMID:18796159 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1558600 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ERN1 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ERN1 mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ERN1 mRNA | CTD | PMID:18796159 |
| 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in decreased expression of ERN1 mRNA | CTD | PMID:19162173 |
| 4-hydroxynon-2-enal | decreases expression | ISO | RGD:1558600 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of ERN1 mRNA | CTD | PMID:19191707 |
| 4-phenylbutyric acid | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] | CTD | PMID:20399799 |
| aflatoxin B1 | increases expression | ISO | RGD:1558600 | 6480464 | Aflatoxin B1 results in increased expression of ERN1 mRNA | CTD | PMID:19770486 |
| all-trans-retinoic acid | increases expression | ISO | RGD:1558600 | 6480464 | Tretinoin results in increased expression of ERN1 protein; more ... | CTD | PMID:22498432 |
| amiloride | multiple interactions | ISO | RGD:1558600 | 6480464 | Amiloride inhibits the reaction [Tunicamycin results in increased phosphorylation of and results in increased activity of ERN1 protein] | CTD | PMID:20015086 |
| apigenin | multiple interactions | ISO | RGD:1558600 | 6480464 | Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein]; more ... | CTD | PMID:20493918 |
| brefeldin A | multiple interactions | ISO | RGD:1558600 | 6480464 | Apigenin inhibits the reaction [Brefeldin A results in increased phosphorylation of ERN1 protein] | CTD | PMID:20493918 |
| brefeldin A | increases phosphorylation | ISO | RGD:1558600 | 6480464 | Brefeldin A results in increased phosphorylation of ERN1 protein | CTD | PMID:20493918 |
| caffeine | multiple interactions | ISO | RGD:1558600 | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of ERN1 mRNA; more ... | CTD | PMID:20230807 |
| capsaicin | increases expression | ISO | RGD:1605125 | 6480464 | Capsaicin results in increased expression of ERN1 protein | CTD | PMID:19699254 PMID:19139269 |
| capsaicin | increases expression | ISO | RGD:1605125 | 6480464 | Capsaicin results in increased expression of ERN1 protein | CTD | PMID:19139269 PMID:19699254 |
| cerulenin | multiple interactions | ISO | RGD:1605125 | 6480464 | Cerulenin affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA] | CTD | PMID:17283163 |
| chloropicrin | increases expression | ISO | RGD:1605125 | 6480464 | chloropicrin results in increased expression of ERN1 protein | CTD | PMID:22516760 |
| choline | multiple interactions | ISO | RGD:1558600 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene | CTD | PMID:20938992 |
| cobalt dichloride | increases expression | ISO | RGD:1605125 | 6480464 | cobaltous chloride results in increased expression of ERN1 mRNA | CTD | PMID:19320972 |
| cocaine | multiple interactions | EXP | | 6480464 | 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; more ... | CTD | PMID:17303341 |
| cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of ERN1 protein | CTD | PMID:17303341 |
| copper(2+) sulfate | increases expression | ISO | RGD:1605125 | 6480464 | Copper Sulfate results in increased expression of ERN1 mRNA | CTD | PMID:19549813 |
| curcumin | decreases expression | ISO | RGD:1605125 | 6480464 | Curcumin results in decreased expression of ERN1 mRNA | CTD | PMID:17999991 |
| cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of ERN1 protein | CTD | PMID:20136702 |
| cyclosporin A | multiple interactions | EXP | | 6480464 | Melatonin promotes the reaction [Cyclosporine results in increased expression of ERN1 protein] | CTD | PMID:20136702 |
| diarsenic trioxide | increases expression | ISO | RGD:1605125 | 6480464 | arsenic trioxide results in increased expression of ERN1 mRNA | CTD | PMID:19176121 |
| diarsenic trioxide | increases expression | ISO | RGD:1605125 | 6480464 | arsenic trioxide results in increased expression of ERN1 mRNA | CTD | PMID:19176121 PMID:22521957 |
| dihydrocapsaicin | multiple interactions | ISO | RGD:1605125 | 6480464 | anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [dihydrocapsaicin results in increased expression of ERN1 protein] | CTD | PMID:19139269 |
| dihydrocapsaicin | increases expression | ISO | RGD:1605125 | 6480464 | dihydrocapsaicin results in increased expression of ERN1 protein | CTD | PMID:19139269 |
| edaravone | increases expression | EXP | | 6480464 | phenylmethylpyrazolone results in increased expression of ERN1 mRNA | CTD | PMID:19558813 |
| ethanol | increases expression | ISO | RGD:1558600 | 6480464 | Ethanol results in increased expression of ERN1 protein | CTD | PMID:18377926 |
| folic acid | multiple interactions | ISO | RGD:1558600 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene | CTD | PMID:20938992 |
| formaldehyde | increases expression | ISO | RGD:1605125 | 6480464 | Formaldehyde results in increased expression of ERN1 mRNA | CTD | PMID:17938736 PMID:20655997 |
| formaldehyde | increases expression | ISO | RGD:1605125 | 6480464 | Formaldehyde results in increased expression of ERN1 mRNA | CTD | PMID:20655997 PMID:17938736 |
| gadolinium trichloride | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein] | CTD | PMID:21198628 |
| gadolinium trichloride | increases expression | EXP | | 6480464 | gadolinium chloride results in increased expression of ERN1 protein | CTD | PMID:21198628 |
| L-methionine | multiple interactions | ISO | RGD:1558600 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ERN1 gene | CTD | PMID:20938992 |
| lead diacetate | increases expression | ISO | RGD:1558600 | 6480464 | lead acetate results in increased expression of ERN1 mRNA | CTD | PMID:21829687 |
| melatonin | multiple interactions | EXP | | 6480464 | Melatonin promotes the reaction [Cyclosporine results in increased expression of ERN1 protein] | CTD | PMID:20136702 |
| methotrexate | affects expression | ISO | RGD:1558600 | 6480464 | Methotrexate affects the expression of ERN1 mRNA | CTD | PMID:18502557 |
| minocycline | increases phosphorylation | EXP | | 6480464 | Minocycline results in increased phosphorylation of ERN1 protein | CTD | PMID:22245251 |
| N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein] | CTD | PMID:21198628 |
| N-methyl-4-phenylpyridinium | multiple interactions | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in increased activity of ERN1 protein | CTD | PMID:12486162 |
| paracetamol | affects expression | ISO | RGD:1558600 | 6480464 | Acetaminophen affects the expression of ERN1 mRNA | CTD | PMID:17562736 |
| paracetamol | increases expression | ISO | RGD:1605125 | 6480464 | Acetaminophen results in increased expression of ERN1 mRNA | CTD | PMID:21420995 |
| paracetamol | increases expression | ISO | RGD:1558600 | 6480464 | Acetaminophen results in increased expression of ERN1 mRNA | CTD | PMID:18544908 |
| paraquat | multiple interactions | ISO | RGD:1605125 | 6480464 | Paraquat promotes the reaction [MAP3K5 protein results in increased phosphorylation of ERN1 protein] | CTD | PMID:20929985 |
| paraquat | increases phosphorylation | EXP | | 6480464 | Paraquat results in increased phosphorylation of ERN1 protein | CTD | PMID:22245251 |
| paraquat | increases phosphorylation | ISO | RGD:1605125 | 6480464 | Paraquat results in increased phosphorylation of ERN1 protein | CTD | PMID:20929985 |
| perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ERN1 mRNA | CTD | PMID:19162173 |
| pirinixic acid | decreases expression | ISO | RGD:1558600 | 6480464 | pirinixic acid results in decreased expression of ERN1 mRNA | CTD | PMID:16985257 |
| pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ERN1 mRNA | CTD | PMID:19162173 |
| pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of ERN1 mRNA | CTD | PMID:19162173 |
| propiconazole | increases expression | ISO | RGD:1558600 | 6480464 | propiconazole results in increased expression of ERN1 mRNA | CTD | PMID:21278054 |
| rotenone | multiple interactions | EXP | | 6480464 | Rotenone results in increased phosphorylation of and results in increased activity of ERN1 protein | CTD | PMID:12486162 |
| streptozocin | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] | CTD | PMID:20399799 |
| streptozocin | increases expression | EXP | | 6480464 | Streptozocin results in increased expression of ERN1 protein modified form | CTD | PMID:20399799 |
| succimer | multiple interactions | ISO | RGD:1558600 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ERN1 mRNA | CTD | PMID:21641980 |
| thapsigargin | multiple interactions | ISO | RGD:1558600 | 6480464 | Apigenin inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein] | CTD | PMID:20493918 |
| thapsigargin | increases expression | ISO | RGD:1605125 | 6480464 | Thapsigargin results in increased expression of ERN1 protein | CTD | PMID:19139269 |
| thapsigargin | increases phosphorylation | ISO | RGD:1558600 | 6480464 | Thapsigargin results in increased phosphorylation of ERN1 protein | CTD | PMID:20493918 |
| tunicamycin | multiple interactions | ISO | RGD:1558600 | 6480464 | Amiloride inhibits the reaction [Tunicamycin results in increased phosphorylation of and results in increased activity of ERN1 protein] | CTD | PMID:20015086 |
| tunicamycin | increases expression | ISO | RGD:1558600 | 6480464 | Tunicamycin results in increased expression of ERN1 mRNA | CTD | PMID:17127020 |
| tunicamycin | increases expression | ISO | RGD:1605125 | 6480464 | Tunicamycin results in increased expression of ERN1 protein | CTD | PMID:19139269 |
| tunicamycin | increases phosphorylation | ISO | RGD:1558600 | 6480464 | Tunicamycin results in increased phosphorylation of ERN1 protein | CTD | PMID:22001960 |
| tunicamycin | increases expression | ISO | RGD:1558600 | 6480464 | Tunicamycin results in increased expression of ERN1 mRNA | CTD | PMID:17127020 PMID:21432213 |