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GENE - TERM ANNOTATION REPORT

8 Annotations Found.

An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Tu W, etal., J Biochem. 2019 May 1;165(5):423-431. doi: 10.1093/jb/mvy120.
  • The annotation has been inferred from sequence orthology with PTEN (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Tu W, etal., J Biochem. 2019 May 1;165(5):423-431. doi: 10.1093/jb/mvy120.
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Curation Notes: associated with hepatitis B;protein:decreased expression:liver (human)


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Rahman MA, etal., Int J Cancer. 2002 Jul 10;100(2):152-7. doi: 10.1002/ijc.10458.
  • The annotation has been inferred from sequence orthology with PTEN (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Rahman MA, etal., Int J Cancer. 2002 Jul 10;100(2):152-7. doi: 10.1002/ijc.10458.
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Qualifier: exacerbates
  • Curation Notes: associated with hepatitis C, liver cirrhosis;protein:decreased expression:liver (human)


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Hu TH, etal., Cancer. 2003 Apr 15;97(8):1929-40. doi: 10.1002/cncr.11266.
  • The annotation has been inferred from sequence orthology with PTEN (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Hu TH, etal., Cancer. 2003 Apr 15;97(8):1929-40. doi: 10.1002/cncr.11266.
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Qualifier: exacerbates
  • Curation Notes: protein:decreased expression:liver (human)


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with PTEN (Homo sapiens) [(EXP) inferred from experiment]
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:27022031


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Li N, etal., Molecules. 2019 Nov 30;24(23). pii: molecules24234384. doi: 10.3390/molecules24234384.
  • 11 additional annotations were made from Li N, etal., Molecules. 2019 Nov 30;24(23). pii: molecules24234384. doi: 10.3390/molecules24234384.
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Qualifier: treatment


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Xu Z, etal., Exp Mol Med. 2018 Jan 5;50(1):e417. doi: 10.1038/emm.2017.158.
  • The annotation has been inferred from sequence orthology with PTEN (Homo sapiens) [(IEP) inferred from expression pattern]
  • 14 additional annotations were made from Xu Z, etal., Exp Mol Med. 2018 Jan 5;50(1):e417. doi: 10.1038/emm.2017.158.
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Qualifier: severity
  • Curation Notes: protein:decreased expression:liver (human)


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Xu Z, etal., Exp Mol Med. 2018 Jan 5;50(1):e417. doi: 10.1038/emm.2017.158.
  • The annotation has been inferred from sequence orthology with Pten (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 14 additional annotations were made from Xu Z, etal., Exp Mol Med. 2018 Jan 5;50(1):e417. doi: 10.1038/emm.2017.158.
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten


    • An association has been curated linking Pten and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
    		•  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Pten (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 949 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 165 papers in RGD have been used to annotate Pten
  • Curation Notes: OMIM:114550


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