Gene: Apoe (apolipoprotein E) Rattus norvegicus
Symbol: Apoe
Name: apolipoprotein E
Description: ENCODES a protein that exhibits beta-amyloid binding; hydroxyapatite binding; lipid transporter activity; INVOLVED IN aging; cellular response to cholesterol; cellular response to growth factor stimulus; PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; Alzheimer disease pathway; ASSOCIATED WITH Alzheimer Disease; Diabetes Mellitus, Experimental; Glomerulonephritis, Membranous; FOUND IN cell surface; cytoplasm; dendrite; INTERACTS WITH 17alpha-ethynylestradiol; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apo-E; APOEA
Allele / Splice: Apoeem8Mcwi   Apoeem7Mcwi   Apoeem9Mcwi  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0180,612,894 - 80,616,820-NCBI
Rat Cytogenetic Map1q21 NCBI
RGSC Genome Assembly v5.0181,878,372 - 81,882,298-NCBI
RGSC Genome Assembly v3.4179,003,634 - 79,006,387-NCBI
Rat Celera Assembly173,813,122 - 73,817,046-NCBI
Genome Assembly 3.1179,081,854 - 79,083,684-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Apoe
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 2138
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-10-01
Status: ACTIVE