GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Apoe | increases response to substance | ISO | Apoe (Mus musculus) | 6480464 | CTD | APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate | PMID:25270622 | Apoe | multiple interactions | ISO | Apoe (Mus musculus) | 6480464 | CTD | [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of ABCG5 protein; [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of ABCG8 protein; [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of CYP7A1 protein; [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of LDLR protein; [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of NR1H3 protein | PMID:25270622 | | ||||||||||||||||||||||
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