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GENE - TERM ANNOTATION REPORT

RGD ID: 2138
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoe
Name: apolipoprotein E
Acc ID: DOID:0110035
Term: Alzheimer's disease 2
Definition: An Alzheimer's disease that is characterized by an association of the apolipoprotein E E4 allele. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pubmed/8346443 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoe ISOAPOE (Homo sapiens)7240710OMIM  
Apoe ISOAPOE (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanism 
Apoe ISOAPOE (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Alzheimer disease 2 | ClinVar Annotator: match by term: Alzheimer disease associated with APOE E4 | ClinVar Annotator: match by term: Late-onset familial alzheimer diseasePMID:10213549 PMID:10799751 PMID:11835377 PMID:11940689 PMID:11940706 PMID:14741101 PMID:15048896 PMID:15146461 PMID:15184602 PMID:15326261 PMID:15557508 PMID:15668424 PMID:18338393 PMID:18979180 PMID:18987351 PMID:19605830 PMID:19846850 PMID:21742527 PMID:22381401 PMID:22949395 PMID:23060451 PMID:23296339 PMID:23571587 PMID:24033266 PMID:24126160 PMID:25741868 PMID:27260402 PMID:28492532 PMID:29842932 PMID:2987927 PMID:32376954 PMID:32808727 PMID:3353383 PMID:35120450 PMID:35628605 PMID:35639372 PMID:3922972 PMID:7263700 PMID:8294487 PMID:8346443 PMID:8350998 PMID:8488843 PMID:8618665 PMID:8644717 PMID:9279208 PMID:9343467 PMID:9360638 PMID:9932938
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