Gene: Tlr4 (toll-like receptor 4) Rattus norvegicus
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Symbol: Tlr4
Name: toll-like receptor 4
Description: ENCODES a protein that exhibits lipopolysaccharide binding; phosphatidylinositol 3-kinase binding; receptor activity; INVOLVED IN cellular response to lipopolysaccharide; cellular response to mechanical stimulus; cellular response to retinoic acid; PARTICIPATES IN Toll-like receptor signaling pathway; titanium dioxide nanoparticle response pathway; Entamoeba histolyca infection pathway; ASSOCIATED WITH Acanthamoeba Keratitis; Acute Kidney Injury; Acute Lung Injury; FOUND IN cell surface; cytoplasm; membrane raft; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: toll4
Orthologs:
Allele / Splice: Tlr4m1Mcwi   Tlr4em1Geh  
Genetic Models: WI-Tlr4em1Geh FHH-Tlr4m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0582,587,424 - 82,601,056 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0586,690,670 - 86,704,302 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4583,564,100 - 83,577,735 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1583,569,212 - 83,582,848 (+)NCBI
Celera579,045,293 - 79,058,928 (+)NCBI
Cytogenetic Map5q24NCBImapview
RH 3.4 Map5643.7RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tlr4
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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RGD Object Information
RGD ID: 3870
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-18
Status: ACTIVE