Gene: Hras (Harvey rat sarcoma virus oncogene) Rattus norvegicus
Symbol: Hras
Name: Harvey rat sarcoma virus oncogene
Description: ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); protein C-terminus binding (ortholog); INVOLVED IN apoptotic process; positive regulation of DNA replication; positive regulation of ERK1 and ERK2 cascade; PARTICIPATES IN endothelin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH abnormal retinal apoptosis; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetic Retinopathy; Mammary Neoplasms, Experimental; FOUND IN intracellular membrane-bounded organelle; plasma membrane; Golgi apparatus (ortholog); INTERACTS WITH (S)-nicotine; 1,2-dichlorobenzene; 1-naphthyl isothiocyanate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: c-H-ras; GTPase HRas; H-Ras-1; Harvey ras1 protein; Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog; HRAS1; p21ras; transforming protein p21
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01214,178,278 - 214,181,686-NCBI
Rat Cytogenetic Map1q41 NCBI
RGSC Genome Assembly v5.01221,095,943 - 221,099,362-NCBI
RGSC Genome Assembly v3.41201,385,705 - 201,388,987-NCBI
Rat Celera Assembly1193,930,281 - 193,933,583-NCBI
Genome Assembly 3.11201,540,000 - 201,542,640-NCBI
RH 3.411437.21 RGD

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Candidate Gene Status
Comparative Map Data
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QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hras
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RGD Object Information
RGD ID: 2827
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-07-28
Status: ACTIVE