Gene: Ttr (transthyretin) Rattus norvegicus
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Symbol: Ttr
Name: transthyretin
Description: ENCODES a protein that exhibits hormone binding; protein heterodimerization activity; identical protein binding (ortholog); INVOLVED IN regulation of receptor activity (inferred); retinol metabolic process (inferred); thyroid hormone metabolic process (inferred); PARTICIPATES IN forkhead class A signaling pathway; retinoic acid metabolic pathway; ASSOCIATED WITH Brain Ischemia; brain ischemia; Alzheimer Disease (ortholog); FOUND IN extracellular space; protein complex; extracellular exosome (ortholog); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LR1; prealbumin; prealbumin, amyloidosis type I; Tbpa; Transthyretin (prealbumin amyloidosis type I); Transthyretin (prealbumin, amyloidosis type I); TT
Orthologs:
Homo sapiens (human) : TTR (transthyretin)  HGNC  AGR
Mus musculus (house mouse) : Ttr (transthyretin)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ttr (transthyretin)
Pan paniscus (bonobo/pygmy chimpanzee) : TTR (transthyretin)
Canis lupus familiaris (dog) : TTR (transthyretin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttr (transthyretin)
more info ...
Is Marker For: QTLs:   Bp46   Scl22  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01815,532,963 - 15,542,180 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01815,307,563 - 15,316,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41812,406,571 - 12,413,680 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11812,433,216 - 12,440,326 (+)NCBI
Celera1811,951,406 - 11,958,617 (+)NCBICelera
Cytogenetic Map18p12NCBI
RH 3.4 Map1891.82RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ttr
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3916
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE