Gene: Tnf (tumor necrosis factor)  Rattus norvegicus
Symbol: Tnf
Name: tumor necrosis factor
Description: ENCODES a protein that exhibits tumor necrosis factor receptor binding; cytokine activity (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process; calcium-mediated signaling; cell activation; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ceramide signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH altered response to myocardial infarction; decreased heart rate; decreased vasodilation; ASSOCIATED WITH Acute Lung Injury; Albuminuria; Anti-Glomerular Basement Membrane Disease; FOUND IN extracellular space; integral to membrane; cell surface (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (-)-perillyl alcohol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cachectin; MGC124630; RATTNF; TNF-a; TNF-alpha; Tnfa; tumor necrosis factor; tumor necrosis factor superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand superfamily member 2; tumor necrosis factor superfamily member 2; tumor necrosis factor superfamily, member 2; Tumor necrosis factor, alpha (cachetin); tumor necrosis factor, alpha (cachetin); tumor necrosis factor-alpha
Orthologs: Homo sapiens : TNF (tumor necrosis factor)  HGNC
Mus musculus : Tnf (tumor necrosis factor)  MGI
Is Marker For: QTLs:   Bp144  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.0206,936,229 - 6,938,847+NCBI
RGSC Genome Assembly v3.4203,661,000 - 3,663,618+NCBI
Rat Celera Assembly204,400,860 - 4,403,478-NCBI
Genome Assembly 3.1203,661,370 - 3,663,010+NCBI
RH 3.42051.3 RGD
RH 3.42051.4 RGD
Model

Launch Genome Browser (GBrowse)

Annotation    (Toggle Detail/Summary View)