Gene: Tnf (tumor necrosis factor) Rattus norvegicus
Symbol: Tnf
Name: tumor necrosis factor
Description: ENCODES a protein that exhibits tumor necrosis factor receptor binding; cytokine activity (ortholog); identical protein binding (ortholog); INVOLVED IN acute inflammatory response; apoptotic process; calcium-mediated signaling; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ceramide signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH altered response to myocardial infarction; decreased heart rate; decreased vasodilation; ASSOCIATED WITH Acute Lung Injury; Albuminuria; Anti-Glomerular Basement Membrane Disease; FOUND IN extracellular space; integral component of membrane; intracellular; INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-pilocarpine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cachectin; MGC124630; RATTNF; TNF-a; TNF-alpha; Tnfa; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor superfamily member 2; tumor necrosis factor superfamily, member 2; tumor necrosis factor-alpha
Is Marker For: QTLs:   Bp144  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0205,189,382 - 5,192,000-NCBI
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.0206,936,229 - 6,938,847+NCBI
RGSC Genome Assembly v3.4203,661,000 - 3,663,618+NCBI
Rat Celera Assembly204,400,860 - 4,403,478-NCBI
RH 3.420  RGD

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