Gene: Comt (catechol-O-methyltransferase) Rattus norvegicus
Symbol: Comt
Name: catechol-O-methyltransferase
Description: ENCODES a protein that exhibits catechol O-methyltransferase activity; INVOLVED IN developmental process; estrogen metabolic process; female pregnancy; PARTICIPATES IN alkaptonuria disease pathway; disulfiram pharmacodynamics pathway; dopamine beta hydroxylase deficiency pathway; ASSOCIATED WITH abnormal dopamine level; ASSOCIATED WITH Brain Injuries; Catalepsy; Diabetes Mellitus, Experimental; FOUND IN axon; cell body; cytosol; INTERACTS WITH (-)-epigallocatechin 3-gallate; (3,4-dihydroxyphenyl)acetic acid; (R)-adrenaline
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: catechol O-methyltransferase; catecholamine-O-methyltransferase
Orthologs:
Allele / Splice: Comtem1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01186,715,981 - 86,735,630 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01189,809,853 - 89,829,568 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41184,561,591 - 84,581,713 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11184,617,363 - 84,622,260 (+)NCBI
Celera1181,345,121 - 81,364,705 (+)NCBI
Cytogenetic Map11q23NCBImapview
RH 3.4 Map11712.2RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Comt
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2379
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE