| (S)-colchicine | decreases expression | ISO | RGD:735767 | 6480464 | Colchicine results in decreased expression of KRT18 protein | CTD | PMID:11259854 |
| 1-naphthyl isothiocyanate | increases expression | ISO | RGD:1557581 | 6480464 | 1-Naphthylisothiocyanate results in increased expression of KRT18 mRNA | CTD | PMID:15913567 |
| 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of KRT18 mRNA | CTD | PMID:17522070 |
| 1-naphthyl isothiocyanate | multiple interactions | ISO | RGD:1557581 | 6480464 | O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT18 mRNA] | CTD | PMID:15913567 |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of KRT18 mRNA | CTD | PMID:12655037 |
| 17beta-estradiol | multiple interactions | ISO | RGD:735767 | 6480464 | diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA]; more ... | CTD | PMID:11179685 |
| 17beta-estradiol | decreases expression | ISO | RGD:735767 | 6480464 | Estradiol results in decreased expression of KRT18 mRNA | CTD | PMID:23019147 |
| 17beta-estradiol | increases expression | ISO | RGD:735767 | 6480464 | Estradiol results in increased expression of KRT18 mRNA | CTD | PMID:11179685 |
| 17beta-estradiol | multiple interactions | ISO | RGD:735767 | 6480464 | KRT18 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]] | CTD | PMID:20061804 |
| 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | RGD:735767 | 6480464 | Metribolone results in increased expression of KRT18 protein | CTD | PMID:17541959 PMID:17152098 |
| 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | RGD:735767 | 6480464 | Metribolone results in increased expression of KRT18 protein | CTD | PMID:17152098 PMID:17541959 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:735767 | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA] | CTD | PMID:11179685 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:735767 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KRT18 mRNA | CTD | PMID:23152189 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KRT18 mRNA | CTD | PMID:20959002 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1557581 | 6480464 | Tetrachlorodibenzodioxin affects the expression of KRT18 mRNA | CTD | PMID:21570461 |
| 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of KRT18 mRNA | CTD | PMID:21346803 |
| 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of KRT18 mRNA | CTD | PMID:21346803 |
| 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:735767 | 6480464 | Fenretinide results in increased expression of KRT18 protein | CTD | PMID:17387344 |
| 5-fluorouracil | multiple interactions | ISO | RGD:735767 | 6480464 | [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of KRT18 protein | CTD | PMID:15754201 |
| 9-cis-retinoic acid | increases expression | ISO | RGD:735767 | 6480464 | alitretinoin results in increased expression of KRT18 mRNA | CTD | PMID:17034753 |
| acrolein | increases metabolic processing | ISO | RGD:735767 | 6480464 | Acrolein results in increased metabolism of KRT18 protein | CTD | PMID:20015449 |
| all-trans-retinoic acid | increases expression | ISO | RGD:735767 | 6480464 | Tretinoin results in increased expression of KRT18 mRNA | CTD | PMID:17034753 |
| all-trans-retinoic acid | increases expression | ISO | RGD:735767 | 6480464 | Tretinoin results in increased expression of KRT18 mRNA | CTD | PMID:21934132 PMID:17034753 |
| all-trans-retinoic acid | increases expression | ISO | RGD:735767 | 6480464 | Tretinoin results in increased expression of KRT18 mRNA | CTD | PMID:17034753 PMID:21934132 |
| all-trans-retinoic acid | increases expression | ISO | RGD:1557581 | 6480464 | Tretinoin results in increased expression of KRT18 mRNA | CTD | PMID:16236135 |
| all-trans-retinoic acid | increases expression | ISO | RGD:735767 | 6480464 | Tretinoin results in increased expression of KRT18 protein | CTD | PMID:17387344 |
| all-trans-retinol | increases expression | ISO | RGD:735767 | 6480464 | Vitamin A results in increased expression of KRT18 mRNA | CTD | PMID:17034753 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of KRT18 mRNA; more ... | CTD | PMID:16483693 |
| arachidonic acid | multiple interactions | ISO | RGD:735767 | 6480464 | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein | CTD | PMID:17034788 |
| arsenic atom | decreases expression | ISO | RGD:735767 | 6480464 | Arsenic results in decreased expression of KRT18 mRNA | CTD | PMID:11134558 PMID:12773770 |
| arsenic atom | decreases expression | ISO | RGD:735767 | 6480464 | Arsenic results in decreased expression of KRT18 mRNA | CTD | PMID:12773770 PMID:11134558 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1557581 | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to KRT18 promoter] | CTD | PMID:19654925 |
| benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of KRT18 protein | CTD | PMID:21467743 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1557581 | 6480464 | Benzo(a)pyrene results in decreased expression of KRT18 mRNA | CTD | PMID:19770486 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:1557581 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of KRT18 mRNA | CTD | PMID:21715664 |
| benzo[a]pyrene | increases expression | ISO | RGD:735767 | 6480464 | Benzo(a)pyrene results in increased expression of KRT18 mRNA | CTD | PMID:20064835 |
| beta-carotene | increases expression | ISO | RGD:735767 | 6480464 | beta Carotene results in increased expression of KRT18 mRNA | CTD | PMID:17034753 |
| bis(2-chloroethyl) sulfide | multiple interactions | ISO | RGD:1557581 | 6480464 | Dimercaprol inhibits the reaction [Mustard Gas results in increased expression of KRT18 mRNA] | CTD | PMID:16377760 |
| bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1557581 | 6480464 | Mustard Gas results in increased expression of KRT18 mRNA | CTD | PMID:16377760 |
| buta-1,3-diene | decreases expression | ISO | RGD:1557581 | 6480464 | 1,3-butadiene results in decreased expression of KRT18 mRNA | CTD | PMID:21147608 |
| cadmium dichloride | increases expression | ISO | RGD:735767 | 6480464 | Cadmium Chloride results in increased expression of KRT18 mRNA | CTD | PMID:12160620 |
| chloroform | increases expression | EXP | | 6480464 | Chloroform results in increased expression of KRT18 mRNA | CTD | PMID:17522070 |
| ciguatoxin CTX1B | affects expression | ISO | RGD:1557581 | 6480464 | Ciguatoxins affects the expression of KRT18 mRNA | CTD | PMID:18353800 |
| clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of KRT18 mRNA | CTD | PMID:17522070 |
| copper(2+) sulfate | increases expression | ISO | RGD:735767 | 6480464 | Copper Sulfate results in increased expression of KRT18 mRNA | CTD | PMID:19549813 |
| cumene | multiple interactions | ISO | RGD:1557581 | 6480464 | [cumene co-treated with KRAS gene mutant form] results in decreased expression of KRT18 mRNA | CTD | PMID:18648096 |
| diarsenic trioxide | decreases response to substance | ISO | RGD:735767 | 6480464 | KRT18 protein results in decreased susceptibility to arsenic trioxide | CTD | PMID:20707922 |
| diarsenic trioxide | increases expression | ISO | RGD:1557581 | 6480464 | arsenic trioxide results in increased expression of KRT18 mRNA | CTD | PMID:15073043 |
| diazoxide | increases expression | ISO | RGD:1557581 | 6480464 | Isoproterenol results in increased expression of KRT18 mRNA | CTD | PMID:21335049 |
| dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of KRT18 mRNA | CTD | PMID:21266533 |
| diethylstilbestrol | decreases expression | ISO | RGD:1557581 | 6480464 | Diethylstilbestrol results in decreased expression of KRT18 mRNA | CTD | PMID:15171707 |
| dimercaprol | multiple interactions | ISO | RGD:1557581 | 6480464 | Dimercaprol inhibits the reaction [Mustard Gas results in increased expression of KRT18 mRNA] | CTD | PMID:16377760 |
| dimethylarsinic acid | decreases expression | EXP | | 6480464 | Cacodylic Acid results in decreased expression of KRT18 mRNA | CTD | PMID:17481689 |
| diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of KRT18 mRNA | CTD | PMID:21551480 |
| docetaxel anhydrous | increases expression | ISO | RGD:735767 | 6480464 | docetaxel results in increased expression of KRT18 protein | CTD | PMID:16685278 |
| docetaxel anhydrous | increases metabolic processing | ISO | RGD:735767 | 6480464 | docetaxel results in increased metabolism of KRT18 protein | CTD | PMID:16685278 |
| doxorubicin | affects response to substance | ISO | RGD:735767 | 6480464 | KRT18 protein affects the susceptibility to Doxorubicin | CTD | PMID:16928833 |
| elemental selenium | increases expression | ISO | RGD:735767 | 6480464 | Selenium results in increased expression of KRT18 mRNA | CTD | PMID:19244175 |
| erythromycin estolate | increases expression | EXP | | 6480464 | Erythromycin Estolate results in increased expression of KRT18 mRNA | CTD | PMID:17522070 |
| estramustine | increases expression | ISO | RGD:735767 | 6480464 | Estramustine results in increased expression of KRT18 protein | CTD | PMID:16685278 |
| ethanol | multiple interactions | ISO | RGD:735767 | 6480464 | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein | CTD | PMID:17034788 |
| ethanol | increases expression | ISO | RGD:735767 | 6480464 | Ethanol results in increased expression of KRT18 protein | CTD | PMID:20621659 |
| fenofibrate | multiple interactions | ISO | RGD:1557581 | 6480464 | [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein | CTD | PMID:18978307 |
| fulvestrant | multiple interactions | ISO | RGD:735767 | 6480464 | KRT18 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]; more ... | CTD | PMID:20061804 |
| fumonisin B1 | increases expression | ISO | RGD:1557581 | 6480464 | fumonisin B1 results in increased expression of KRT18 mRNA | CTD | PMID:16221962 |
| genistein | increases expression | ISO | RGD:735767 | 6480464 | Genistein results in increased expression of KRT18 protein | CTD | PMID:20884965 |
| genistein | multiple interactions | ISO | RGD:735767 | 6480464 | ESR1 promotes the reaction [Genistein results in increased expression of KRT18 protein]; more ... | CTD | PMID:20884965 |
| glutathione | increases expression | EXP | | 6480464 | Glutathione deficiency results in increased expression of KRT18 mRNA | CTD | PMID:15345336 |
| heparin | increases expression | ISO | RGD:735767 | 6480464 | Heparin results in increased expression of KRT18 protein | CTD | PMID:15671997 |
| hydrazine | increases expression | EXP | | 6480464 | hydrazine results in increased expression of KRT18 protein | CTD | PMID:15370871 |
| isoprenaline | increases expression | ISO | RGD:1557581 | 6480464 | Isoproterenol results in increased expression of KRT18 mRNA | CTD | PMID:21335049 |
| lovastatin | decreases expression | ISO | RGD:1557581 | 6480464 | Lovastatin results in decreased expression of KRT18 mRNA | CTD | PMID:20493250 |
| methotrexate | affects expression | ISO | RGD:1557581 | 6480464 | Methotrexate affects the expression of KRT18 mRNA | CTD | PMID:18502557 |
| methylarsonic acid | decreases expression | EXP | | 6480464 | monomethylarsonic acid results in decreased expression of KRT18 mRNA | CTD | PMID:17481689 |
| microcystin-LR | increases expression | ISO | RGD:1557581 | 6480464 | cyanoginosin LR results in increased expression of KRT18 mRNA | CTD | PMID:17654400 |
| microcystin-LR | multiple interactions | ISO | RGD:735767 | 6480464 | SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT18 protein]; more ... | CTD | PMID:22960429 |
| microcystin-LR | increases phosphorylation | ISO | RGD:735767 | 6480464 | cyanoginosin LR results in increased phosphorylation of KRT18 protein | CTD | PMID:22960429 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1557581 | 6480464 | [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT18 protein | CTD | PMID:20101389 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein | CTD | PMID:20935162 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of KRT18 protein | CTD | PMID:20935162 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT18 mRNA; more ... | CTD | PMID:19409407 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1557581 | 6480464 | [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein | CTD | PMID:18978307 |
| N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of KRT18 mRNA | CTD | PMID:17072980 |
| nevirapine | increases expression | ISO | RGD:735767 | 6480464 | Nevirapine results in increased expression of KRT18 protein | CTD | PMID:19152342 |
| paracetamol | affects expression | ISO | RGD:1557581 | 6480464 | Acetaminophen affects the expression of KRT18 mRNA | CTD | PMID:17562736 |
| paracetamol | multiple interactions | ISO | RGD:1557581 | 6480464 | dioscin inhibits the reaction [Acetaminophen results in increased expression of KRT18 protein] | CTD | PMID:22939915 |
| paracetamol | increases expression | ISO | RGD:1557581 | 6480464 | Acetaminophen results in increased expression of KRT18 protein | CTD | PMID:22939915 |
| paracetamol | decreases expression | ISO | RGD:735767 | 6480464 | Acetaminophen results in decreased expression of KRT18 mRNA | CTD | PMID:21420995 |
| paracetamol | increases cleavage | ISO | RGD:1557581 | 6480464 | Acetaminophen results in increased cleavage of KRT18 protein | CTD | PMID:19783637 |
| perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of KRT18 mRNA | CTD | PMID:19162173 |
| phenobarbital | multiple interactions | ISO | RGD:1557581 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of KRT18 mRNA] | CTD | PMID:19482888 |
| phenobarbital | multiple interactions | EXP | | 6480464 | [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein | CTD | PMID:20935162 |
| phenobarbital | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT18 mRNA; more ... | CTD | PMID:19409407 |
| phenobarbital | increases expression | ISO | RGD:1557581 | 6480464 | Phenobarbital results in increased expression of KRT18 mRNA | CTD | PMID:19482888 |
| phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:1557581 | 6480464 | [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNA | CTD | PMID:16368122 |
| phosgene | affects expression | ISO | RGD:1557581 | 6480464 | Phosgene affects the expression of KRT18 mRNA | CTD | PMID:16300373 |
| piperonyl butoxide | multiple interactions | ISO | RGD:1557581 | 6480464 | [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT18 protein | CTD | PMID:20101389 |
| pirinixic acid | decreases expression | ISO | RGD:1557581 | 6480464 | pirinixic acid results in decreased expression of KRT18 mRNA | CTD | PMID:17426115 PMID:18445702 |
| pirinixic acid | decreases expression | ISO | RGD:1557581 | 6480464 | pirinixic acid results in decreased expression of KRT18 mRNA | CTD | PMID:18445702 PMID:17426115 |
| pirinixic acid | increases expression | ISO | RGD:1557581 | 6480464 | pirinixic acid results in increased expression of KRT18 mRNA | CTD | PMID:16221962 |
| progesterone | multiple interactions | ISO | RGD:1557581 | 6480464 | NCOA2 protein affects the reaction [Progesterone results in decreased expression of KRT18 mRNA] | CTD | PMID:17556502 |
| progesterone | decreases expression | ISO | RGD:1557581 | 6480464 | Progesterone results in decreased expression of KRT18 mRNA | CTD | PMID:17556502 |
| pyrogallol | increases expression | ISO | RGD:1557581 | 6480464 | Pyrogallol results in increased expression of KRT18 mRNA | CTD | PMID:20362636 |
| selenium atom | increases expression | ISO | RGD:735767 | 6480464 | Selenium results in increased expression of KRT18 mRNA | CTD | PMID:19244175 |
| tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of KRT18 mRNA | CTD | PMID:17522070 |
| tetrachloromethane | affects expression | ISO | RGD:1557581 | 6480464 | Carbon Tetrachloride affects the expression of KRT18 mRNA | CTD | PMID:17484886 |
| tetracycline | increases expression | EXP | | 6480464 | Tetracycline results in increased expression of KRT18 mRNA | CTD | PMID:17522070 |
| thioacetamide | multiple interactions | ISO | RGD:1557581 | 6480464 | KRT18 protein affects the reaction [Thioacetamide results in increased expression of MMP2 mRNA]; more ... | CTD | PMID:18395095 |
| thioacetamide | increases expression | ISO | RGD:1557581 | 6480464 | Thioacetamide results in increased expression of KRT18 mRNA | CTD | PMID:18395095 |
| titanium dioxide | increases phosphorylation | ISO | RGD:735767 | 6480464 | titanium dioxide results in increased phosphorylation of KRT18 protein | CTD | PMID:21439344 |
| trimethylarsine oxide | decreases expression | EXP | | 6480464 | trimethylarsine oxide results in decreased expression of KRT18 mRNA | CTD | PMID:17481689 |
| ursodeoxycholic acid | decreases expression | EXP | | 6480464 | Ursodeoxycholic Acid results in decreased expression of KRT18 mRNA | CTD | PMID:15885361 |
| valproic acid | increases expression | ISO | RGD:1557581 | 6480464 | Valproic Acid results in increased expression of KRT18 mRNA | CTD | PMID:15345369 |
| valproic acid | affects expression | ISO | RGD:1557581 | 6480464 | Valproic Acid affects the expression of KRT18 mRNA | CTD | PMID:17292431 |
| vancomycin | decreases expression | ISO | RGD:1557581 | 6480464 | Vancomycin results in decreased expression of KRT18 mRNA | CTD | PMID:18930951 |
| vinorelbine | increases expression | ISO | RGD:735767 | 6480464 | vinorelbine results in increased expression of KRT18 protein | CTD | PMID:16685278 |
| vinorelbine | increases metabolic processing | ISO | RGD:735767 | 6480464 | vinorelbine results in increased metabolism of KRT18 protein | CTD | PMID:16685278 |