Cdkn2b (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4))

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Keyword

Gene: Cdkn2b (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) Rattus norvegicus

Symbol:

Cdkn2b

Name:

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Description:

ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN negative regulation of cell proliferation; positive regulation of epithelial cell differentiation; response to cytokine stimulus; PARTICIPATES IN cell cycle pathway, mitotic; small cell lung cancer pathway; transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH Endometrial Neoplasms; Carcinoma, Transitional Cell (ortholog); Cervical Intraepithelial Neoplasia (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH ammonium chloride; chromium(6+); dichlorine

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

cyclin dependent kinase inhibitor 2B; Cyclin dependent kinase inhibitor 2B (p15 inhibits CDK4); Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase 4 inhibitor B; p14-INK4b; p15; p15-INK4b

Orthologs:

Homo sapiens : CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) HGNC
Mus musculus : Cdkn2b (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) MGI

Is Marker For:

QTLs: Tcas11

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	5	q32		NCBI
RGSC Genome Assembly v5.0	5	111,820,712 - 111,826,334	-	NCBI
RGSC Genome Assembly v3.4	5	108,939,669 - 108,945,293	-	NCBI
Rat Celera Assembly	5	102,728,741 - 102,734,365	-	NCBI
Genome Assembly 3.1	5	108,946,492 - 108,950,551	-	NCBI