Gene: Dnmt1 (DNA (cytosine-5-)-methyltransferase 1) Rattus norvegicus
Symbol: Dnmt1
Name: DNA (cytosine-5-)-methyltransferase 1
Description: ENCODES a protein that exhibits DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; double-stranded DNA binding; INVOLVED IN aging; brain development; cellular response to lead ion; PARTICIPATES IN DNA modification pathway; methionine cycle/metabolic pathway; cysteine and methionine metabolic pathway; ASSOCIATED WITH Brain Injuries; Carcinogenesis; Choline Deficiency; FOUND IN cytoplasm; neuronal cell body; nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-methylcholanthrene
Type: protein-coding
Also known as: DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase (cytosine-5) 1; DNA methyltransferase I; DNA MTase RnoIP; m.RnoIP; MCMT
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: suggests misassembly
RGSC Genome Assembly v6.0821,922,515 - 21,968,495-NCBI
Rat Cytogenetic Map8q13 NCBI
RGSC Genome Assembly v5.0821,978,830 - 22,024,656-NCBI
RGSC Genome Assembly v3.4819,926,995 - 19,973,256-NCBI
Rat Celera Assembly820,835,612 - 20,881,380-NCBI
Genome Assembly 3.1819,927,666 - 19,973,220-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dnmt1
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RGD Object Information
RGD ID: 620979
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE