GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dnmt1 | decreases response to substance | EXP | | 6480464 | CTD | DNMT1 protein results in decreased susceptibility to Hydrogen Peroxide | PMID:18314485 | Dnmt1 | decreases response to substance | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | DNMT1 protein results in decreased susceptibility to Hydrogen Peroxide | PMID:18314485 | Dnmt1 | increases expression | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide results in increased expression of DNMT1 mRNA; Hydrogen Peroxide results in increased expression of DNMT1 protein | PMID:18314485 PMID:27655674 | Dnmt1 | multiple interactions | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased methylation of DNMT1 promoter | PMID:29854080 | |
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