GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dnmt1 | decreases expression | EXP | | 6480464 | CTD | Arsenic results in decreased expression of DNMT1 protein | PMID:9380733 | Dnmt1 | increases expression | EXP | | 6480464 | CTD | Arsenic results in increased expression of DNMT1 mRNA | PMID:9380733 | Dnmt1 | affects methylation | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Arsenic affects the methylation of DNMT1 gene | PMID:25304211 | Dnmt1 | affects response to substance | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | DNMT1 gene SNP affects the susceptibility to Arsenic | PMID:27292127 PMID:31864032 | Dnmt1 | decreases expression | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Arsenic results in decreased expression of DNMT1 mRNA | PMID:35490796 | Dnmt1 | increases expression | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Arsenic results in increased expression of DNMT1 mRNA | PMID:27838757 | Dnmt1 | multiple interactions | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Folic Acid inhibits the reaction [Arsenic results in decreased expression of DNMT1 mRNA] | PMID:35490796 | Dnmt1 | multiple interactions | ISO | Dnmt1 (Mus musculus) | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DNMT1 protein | PMID:34952004 | |
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