GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dnmt1 | affects activity | ISO | Dnmt1 (Mus musculus) | 6480464 | CTD | Folic Acid affects the activity of DNMT1 protein | PMID:16855792 | Dnmt1 | affects expression | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Folic Acid affects the expression of DNMT1 mRNA | PMID:17311948 PMID:26492244 | Dnmt1 | affects expression | ISO | Dnmt1 (Mus musculus) | 6480464 | CTD | Folic Acid affects the expression of DNMT1 mRNA | PMID:29986310 | Dnmt1 | increases expression | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | Folic Acid results in increased expression of DNMT1 mRNA | PMID:23219837 | Dnmt1 | increases expression | ISO | Dnmt1 (Mus musculus) | 6480464 | CTD | Folic Acid results in increased expression of DNMT1 mRNA; Folic Acid results in increased expression of DNMT1 protein | PMID:30920123 | Dnmt1 | multiple interactions | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | APP protein affects the reaction [Folic Acid affects the expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Arsenic results in decreased expression of DNMT1 mRNA] | PMID:26492244 PMID:35490796 | Dnmt1 | multiple interactions | ISO | Dnmt1 (Mus musculus) | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of DNMT1 mRNA; Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT1 mRNA]; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA] | PMID:20978746 PMID:22206623 PMID:28422052 PMID:28475147 | |
Go Back to source page | Continue to Ontology report |