GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dnmt1 | decreases expression | EXP | | 6480464 | CTD | Cisplatin results in decreased expression of DNMT1 protein | PMID:19723570 | Dnmt1 | decreases response to substance | EXP | | 6480464 | CTD | DNMT1 protein results in decreased susceptibility to Cisplatin | PMID:18314485 | Dnmt1 | multiple interactions | EXP | | 6480464 | CTD | [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein | PMID:19723570 | Dnmt1 | decreases response to substance | ISO | DNMT1 (Homo sapiens) | 6480464 | CTD | DNMT1 protein results in decreased susceptibility to Cisplatin | PMID:18314485 PMID:21458988 | |
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