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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620979
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnmt1
Name: DNA methyltransferase 1
Acc ID: CHEBI:4911
Term: etoposide
Definition: A furonaphthodioxole that has formula C29H32O13.
Chemical ID: MESH:D005047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnmt1decreases response to substanceEXP 6480464CTDDNMT1 protein results in decreased susceptibility to EtoposidePMID:18314485
Dnmt1decreases response to substanceISODNMT1 (Homo sapiens)6480464CTDDNMT1 protein results in decreased susceptibility to EtoposidePMID:18314485
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