Gene: Pon1 (paraoxonase 1) Rattus norvegicus
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Symbol: Pon1
Name: paraoxonase 1
Description: ENCODES a protein that exhibits aryldialkylphosphatase activity; arylesterase activity (ortholog); calcium ion binding (ortholog); INVOLVED IN lipid metabolic process; response to fatty acid; response to fluoride; PARTICIPATES IN clopidogrel pharmacodynamics pathway; clopidogrel pharmacokinetics pathway; organophosphate response pathway; ASSOCIATED WITH Hyperlipoproteinemias; Spinal Cord Injuries; Acute Coronary Syndrome (ortholog); FOUND IN extracellular space; intracellular membrane-bounded organelle; blood microparticle (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-esterase 1; aromatic esterase 1; PON 1; serum aryldialkylphosphatase 1; serum paraoxonase/arylesterase 1
Orthologs:
Homo sapiens (human) : PON1 (paraoxonase 1)  HGNC  AGR
Mus musculus (house mouse) : Pon1 (paraoxonase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Pon1 (paraoxonase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PON1 (paraoxonase 1)
Canis lupus familiaris (dog) : PON1 (paraoxonase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pon1 (paraoxonase 1)
more info ...
Allele / Splice: Pon1em1Mcwi   Pon1em2Mcwi   Pon1em3Mcwi  
Genetic Models: SS-Pon1em2Mcwi SS-Pon1em3Mcwi SS-Pon1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0430,249,749 - 30,276,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0430,156,712 - 30,183,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4429,936,314 - 29,964,821 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1429,975,057 - 30,003,299 (-)NCBI
Celera428,821,674 - 28,848,125 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pon1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620062
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE