Gene: Smo (smoothened, frizzled class receptor) Rattus norvegicus
Symbol: Smo
Name: smoothened, frizzled class receptor
Description: ENCODES a protein that exhibits drug binding (ortholog); patched binding (ortholog); INVOLVED IN axon extension involved in axon guidance; facial nerve development; neuron projection regeneration; PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; basal cell carcinoma pathway; ASSOCIATED WITH Ocular Hypertension; Pancreatitis; Seizures; FOUND IN axonal growth cone; cytoplasm; dendrite; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Smoh; Smoothened; smoothened homolog; smoothened homolog (Drosophila); smoothened, frizzled family receptor
Orthologs:
Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0457,019,941 - 57,041,779 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0456,787,102 - 56,809,935 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4456,623,494 - 56,645,571 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1456,898,313 - 56,920,866 (+)NCBI
Celera453,450,322 - 53,474,674 (+)NCBI
Cytogenetic Map4q22NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Smo
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3726
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-23
Status: ACTIVE