Gene: Stat3 (signal transducer and activator of transcription 3 (acute-phase response factor))  Rattus norvegicus

Symbol: Stat3
Name: signal transducer and activator of transcription 3 (acute-phase response factor)
Description: ENCODES a protein that exhibits CCR5 chemokine receptor binding; DNA binding; glucocorticoid receptor binding; INVOLVED IN acute-phase response; negative regulation of cell death; response to cytokine stimulus; PARTICIPATES IN Interleukin-10 signaling pathway; epidermal growth factor/neuregulin signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH Brain Injuries; Diabetes Mellitus, Experimental; Non-alcoholic Fatty Liver Disease; FOUND IN cytoplasm; nucleus; plasma membrane (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (R)-mevalonic acid; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93551; signal transducer and activator of transcription 3
Orthologs: Homo sapiens : STAT3 (signal transducer and activator of transcription 3 (acute-phase response factor))  HGNC
Mus musculus : Stat3 (signal transducer and activator of transcription 3)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map10q32.1 NCBI
RGSC Genome Assembly v5.01088,584,610 - 88,638,724-NCBI
RGSC Genome Assembly v3.41089,821,078 - 89,872,970-NCBI
Rat Celera Assembly1084,529,054 - 84,580,831-NCBI
Genome Assembly 3.11089,835,448 - 89,887,340-NCBI
RH 3.410837.0 RGD
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Stat3
Entrez Gene
Ensembl Gene
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Vista
Vista + UCSC

RGD Object Information
RGD ID: 3772
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-06-04
Status: ACTIVE