Gene: Fh (fumarate hydratase)  Rattus norvegicus

Symbol: Fh
Name: fumarate hydratase
Description: ENCODES a protein that exhibits fumarate hydratase activity; INVOLVED IN fumarate metabolic process; malate metabolic process; tricarboxylic acid cycle; PARTICIPATES IN citric acid cycle pathway; altered citric acid cycle pathway; renal cell cancer pathway; ASSOCIATED WITH Carcinoma, Renal Cell (ortholog); Fumaric aciduria (ortholog); HYPERCHOLESTEROLEMIA, FAMILIAL (ortholog); FOUND IN mitochondrion; INTERACTS WITH (R)-adrenaline; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fh1; fumarase; fumarate hydratase 1; fumarate hydratase, mitochondrial; MGC105468
Orthologs: Homo sapiens : FH (fumarate hydratase)  HGNC
Mus musculus : Fh1 (fumarate hydratase 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map13q25 NCBI
RGSC Genome Assembly v5.01398,116,496 - 98,142,636-NCBI
RGSC Genome Assembly v3.41391,329,837 - 91,355,722-NCBI
Rat Celera Assembly1387,123,119 - 87,148,786-NCBI
Genome Assembly 3.11391,518,725 - 91,544,617-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fh
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RGD Object Information
RGD ID: 2614
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE