Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | UBE2E2 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | UBE2E2 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
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# | Reference Title | Reference Citation |
1. | Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score. | Eze IC, etal., Environ Int. 2016 Sep;94:263-271. doi: 10.1016/j.envint.2016.04.032. Epub 2016 Jun 6. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:9371400 | PMID:12477932 | PMID:16428300 | PMID:20061386 | PMID:21628527 | PMID:27914986 |
Ube2e2 (Rattus norvegicus - Norway rat) |
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UBE2E2 (Homo sapiens - human) |
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Ube2e2 (Mus musculus - house mouse) |
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Ube2e2 (Chinchilla lanigera - long-tailed chinchilla) |
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UBE2E2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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UBE2E2 (Canis lupus familiaris - dog) |
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Ube2e2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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UBE2E2 (Sus scrofa - pig) |
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LOC103241760 (Chlorocebus sabaeus - green monkey) |
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Variants in Ube2e2
731 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D15Got11 |
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D15Mco16 |
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D3S3993 |
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RH129032 |
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D4Mit282 |
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AW532084 |
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BE120096 |
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RH141730 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 36 | 45 | 35 | 11 | 35 | 1 | 3 | 74 | 35 | 40 | 11 | 1 |
Low | 7 | 12 | 6 | 8 | 6 | 7 | 8 | 1 | 7 | ||||
Below cutoff |
RefSeq Transcripts | NM_001108371 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001399659 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NM_001399660 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NM_001399661 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006251699 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH474010 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JAXUCZ010000015 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000046879 ⟹ ENSRNOP00000049082 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000105543 ⟹ ENSRNOP00000087029 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001108371 ⟹ NP_001101841 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | NM_001399659 ⟹ NP_001386588 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001399660 ⟹ NP_001386589 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001399661 ⟹ NP_001386590 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_001101841 | (Get FASTA) | NCBI Sequence Viewer |
NP_001386588 | (Get FASTA) | NCBI Sequence Viewer | |
NP_001386589 | (Get FASTA) | NCBI Sequence Viewer | |
NP_001386590 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL94076 | (Get FASTA) | NCBI Sequence Viewer |
EDL94077 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000049082 | ||
ENSRNOP00000049082.4 | |||
ENSRNOP00000087029 | |||
ENSRNOP00000087029.1 |
RefSeq Acc Id: | NP_001101841 ⟸ NM_001108371 |
- Peptide Label: | isoform 1 |
- UniProtKB: | D3ZYE1 (UniProtKB/TrEMBL), A6K030 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000049082 ⟸ ENSRNOT00000046879 |
RefSeq Acc Id: | ENSRNOP00000087029 ⟸ ENSRNOT00000105543 |
RefSeq Acc Id: | NP_001386589 ⟸ NM_001399660 |
- Peptide Label: | isoform 2 |
- UniProtKB: | A0A8I6A2G8 (UniProtKB/TrEMBL), A6K029 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | NP_001386588 ⟸ NM_001399659 |
- Peptide Label: | isoform 2 |
- UniProtKB: | A0A8I6A2G8 (UniProtKB/TrEMBL), A6K029 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | NP_001386590 ⟸ NM_001399661 |
- Peptide Label: | isoform 2 |
- UniProtKB: | A0A8I6A2G8 (UniProtKB/TrEMBL), A6K029 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D3ZYE1-F1-model_v2 | AlphaFold | D3ZYE1 | 1-126 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1305644 | AgrOrtholog |
BioCyc Gene | G2FUF-14476 | BioCyc |
BioCyc Pathway | PWY-7511 [protein ubiquitination] | BioCyc |
BioCyc Pathway Image | PWY-7511 | BioCyc |
Ensembl Genes | ENSRNOG00000032690 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000046879 | ENTREZGENE |
ENSRNOT00000046879.4 | UniProtKB/TrEMBL | |
ENSRNOT00000105543 | ENTREZGENE | |
ENSRNOT00000105543.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.10.110.10 | UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7127579 | IMAGE-MGC_LOAD |
IMAGE:7382303 | IMAGE-MGC_LOAD | |
InterPro | UBQ-conjugat_E2 | UniProtKB/TrEMBL |
UBQ-conjugating_AS | UniProtKB/TrEMBL | |
UBQ-conjugating_enzyme/RWD | UniProtKB/TrEMBL | |
KEGG Report | rno:361013 | UniProtKB/TrEMBL |
MGC_CLONE | MGC:116336 | IMAGE-MGC_LOAD |
MGC:94146 | IMAGE-MGC_LOAD | |
NCBI Gene | 361013 | ENTREZGENE |
PANTHER | UBIQUITIN-CONJUGATING ENZYME E2 | UniProtKB/TrEMBL |
UBIQUITIN-CONJUGATING ENZYME E2 E1 | UniProtKB/TrEMBL | |
UBIQUITIN-CONJUGATING ENZYME E2 E2 | UniProtKB/TrEMBL | |
Pfam | UQ_con | UniProtKB/TrEMBL |
PhenoGen | Ube2e2 | PhenoGen |
PROSITE | UBIQUITIN_CONJUGAT_1 | UniProtKB/TrEMBL |
UBIQUITIN_CONJUGAT_2 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000032690 | RatGTEx |
SMART | UBCc | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF54495 | UniProtKB/TrEMBL |
UniProt | A0A8I6A2G8 | ENTREZGENE, UniProtKB/TrEMBL |
A6K029 | ENTREZGENE, UniProtKB/TrEMBL | |
A6K030 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZYE1 | ENTREZGENE, UniProtKB/TrEMBL | |
Q4KLJ5_RAT | UniProtKB/TrEMBL | |
Q6AY98_RAT | UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2013-05-24 | Ube2e2 | ubiquitin-conjugating enzyme E2E 2 | LOC683661 | similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | Data merged from RGD:1584491 | 1643240 | APPROVED |
2011-08-01 | Ube2e2 | ubiquitin-conjugating enzyme E2E 2 | Ube2e2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2006-11-19 | LOC683661 | similar to ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2005-12-06 | Ube2e2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | Ube2e2_predicted | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) (predicted) | Symbol and Name updated | 1559027 | APPROVED |
2005-01-12 | Ube2e2_predicted | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |