Cebpd (CCAAT/enhancer binding protein delta) - Rat Genome Database

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Gene: Cebpd (CCAAT/enhancer binding protein delta) Rattus norvegicus
Analyze
Symbol: Cebpd
Name: CCAAT/enhancer binding protein delta
RGD ID: 2328
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human CEBPD (CCAAT enhancer binding protein delta); PARTICIPATES IN forkhead class A signaling pathway; interleukin-6 signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: c/EBP delta; C/EBP-delta; C/EBPd; C/EBPdelta; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer-binding protein delta; CCAAT/enhancerbinding, protein (C/EBP) delta; CELF; transcription factor CELF
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81198,268,856 - 98,269,994 (+)NCBIGRCr8
mRatBN7.21184,764,670 - 84,765,808 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1184,764,565 - 84,765,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1193,496,641 - 93,497,779 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01186,157,792 - 86,158,930 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,211,385 - 85,212,523 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,008,008 - 89,009,146 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,008,008 - 89,009,146 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,069,758 - 92,070,896 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1183,507,971 - 83,509,109 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-amphetamine  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-naphthoflavone  (ISO)
amphetamine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
calciol  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
chloropicrin  (ISO)
chloroprene  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
ciglitazone  (ISO)
ciguatoxin CTX1B  (ISO)
ciprofloxacin  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
corticosterone  (EXP,ISO)
coumestrol  (ISO)
cucurbitacin B  (ISO)
cumene  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endrin  (ISO)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (EXP)
flavonoids  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (EXP,ISO)
furan  (EXP)
Genipin  (ISO)
genistein  (ISO)
glafenine  (EXP)
glucose  (ISO)
glycyrrhizinic acid  (ISO)
glyphosate  (EXP)
hexanal  (EXP)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
imidacloprid  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
inulin  (ISO)
irinotecan  (EXP)
isoflavones  (ISO)
isoniazide  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
lactacystin  (ISO)
lead(0)  (ISO)
linalool  (EXP)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (EXP)
mercury(0)  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylmercury chloride  (EXP,ISO)
methylparaben  (ISO)
microcystin-LR  (ISO)
MK-2206  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nicotinic acid  (ISO)
ozone  (EXP,ISO)
paclitaxel  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
pomalidomide  (ISO)
potassium chromate  (ISO)
potassium cyanide  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
pyrazinecarboxamide  (EXP)
pyridaben  (ISO)
quercetin  (ISO)
quinomethionate  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rimonabant  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium dichromate  (EXP)
sorafenib  (ISO)
streptozocin  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
temozolomide  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP,ISO)
undecane  (EXP)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
zaragozic acid A  (EXP,ISO)
zearalenone  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. cDNA cloning of a novel C/EBP-related factor. Kageyama R, etal., J Biol Chem 1991 Aug 15;266(23):15525-31.
4. Role of C/EBP proteins in hepatic and vascular smooth muscle transcription of human NHE1 gene. Kolyada AY, etal., Am J Physiol. 1995 Dec;269(6 Pt 1):C1408-16.
5. Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells. Mason RJ, etal., J Clin Invest 2003 Jul;112(2):244-55.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle. Penner G, etal., Am J Physiol Regul Integr Comp Physiol 2002 Feb;282(2):R439-44.
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells. Sekine O, etal., J Biol Chem 2002 Sep 27;277(39):36631-9.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14. The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein. Won JS, etal., J Neurosci 2003 Aug 20;23(20):7470-8.
Additional References at PubMed
PMID:11940593   PMID:12177065   PMID:12821655   PMID:12857754   PMID:14600146   PMID:15175325   PMID:15669083   PMID:15716114   PMID:15833715   PMID:16632469   PMID:17180354   PMID:17384995  
PMID:17636036   PMID:17888405   PMID:17910034   PMID:18559338   PMID:18632661   PMID:21249617   PMID:21492414   PMID:21795542   PMID:21980073   PMID:22347430   PMID:23426691   PMID:24029230  
PMID:26187065   PMID:29482641  


Genomics

Comparative Map Data
Cebpd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81198,268,856 - 98,269,994 (+)NCBIGRCr8
mRatBN7.21184,764,670 - 84,765,808 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1184,764,565 - 84,765,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1193,496,641 - 93,497,779 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01186,157,792 - 86,158,930 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,211,385 - 85,212,523 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,008,008 - 89,009,146 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,008,008 - 89,009,146 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,069,758 - 92,070,896 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1183,507,971 - 83,509,109 (+)NCBICelera
Cytogenetic Map11q23NCBI
CEBPD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38847,736,913 - 47,738,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl847,736,913 - 47,738,164 (-)EnsemblGRCh38hg38GRCh38
GRCh37848,649,475 - 48,650,726 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36848,812,029 - 48,813,279 (-)NCBINCBI36Build 36hg18NCBI36
Build 34848,812,028 - 48,813,323NCBI
Celera844,634,626 - 44,635,876 (-)NCBICelera
Cytogenetic Map8q11.21NCBI
HuRef844,112,391 - 44,113,009 (-)NCBIHuRef
CHM1_1848,701,363 - 48,702,613 (-)NCBICHM1_1
T2T-CHM13v2.0848,112,630 - 48,113,881 (-)NCBIT2T-CHM13v2.0
Cebpd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391615,705,150 - 15,707,409 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1615,705,150 - 15,708,895 (+)EnsemblGRCm39 Ensembl
GRCm381615,887,286 - 15,889,545 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1615,887,286 - 15,891,031 (+)EnsemblGRCm38mm10GRCm38
MGSCv371615,887,379 - 15,889,638 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361615,800,864 - 15,803,123 (+)NCBIMGSCv36mm8
Celera1616,458,567 - 16,460,826 (+)NCBICelera
Cytogenetic Map16A2NCBI
cM Map1610.09NCBI
Cebpd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554547,711,010 - 7,711,680 (-)NCBIChiLan1.0ChiLan1.0
CEBPD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2763,372,971 - 63,374,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1839,066,730 - 39,068,023 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0844,167,256 - 44,168,545 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CEBPD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13574,994 - 77,816 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3588,087 - 89,238 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03525,897 - 27,048 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13510,912 - 12,063 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03529,258 - 30,409 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0351,364,455 - 1,365,597 (+)NCBIUU_Cfam_GSD_1.0
Cebpd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530379,729,245 - 79,730,813 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365904,919,862 - 4,920,612 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEBPD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl479,872,939 - 79,874,477 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1479,872,863 - 79,874,481 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2487,368,896 - 87,370,587 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CEBPD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1843,873,075 - 43,874,375 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603998,196,146 - 98,197,762 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cebpd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247357,721,633 - 7,722,445 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247357,721,564 - 7,722,823 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cebpd
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:160
Count of miRNA genes:113
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000074586
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat

Markers in Region
RH94765  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21184,764,710 - 84,764,898 (+)MAPPERmRatBN7.2
Rnor_6.01189,008,049 - 89,008,236NCBIRnor6.0
Rnor_5.01192,069,799 - 92,069,986UniSTSRnor5.0
Celera1183,508,012 - 83,508,199UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 2 4 2 9 10 2
Low 3 43 57 41 11 41 6 7 72 33 32 1 6
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000074586   ⟹   ENSRNOP00000064025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1184,764,565 - 84,765,829 (+)Ensembl
Rnor_6.0 Ensembl1189,008,008 - 89,009,146 (+)Ensembl
RefSeq Acc Id: NM_013154   ⟹   NP_037286
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81198,268,856 - 98,269,994 (+)NCBI
mRatBN7.21184,764,670 - 84,765,808 (+)NCBI
Rnor_6.01189,008,008 - 89,009,146 (+)NCBI
Rnor_5.01192,069,758 - 92,070,896 (+)NCBI
Celera1183,507,971 - 83,509,109 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_037286 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40913 (Get FASTA)   NCBI Sequence Viewer  
  BAC55108 (Get FASTA)   NCBI Sequence Viewer  
  EDL77845 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064025
  ENSRNOP00000064025.1
  ENSRNOP00055004791
  ENSRNOP00060003347
  ENSRNOP00065010139
GenBank Protein Q03484 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_037286   ⟸   NM_013154
- UniProtKB: Q03484 (UniProtKB/Swiss-Prot),   A6JSR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000064025   ⟸   ENSRNOT00000074586
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q03484-F1-model_v2 AlphaFold Q03484 1-268 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698346
Promoter ID:EPDNEW_R8871
Type:single initiation site
Name:Cebpd_1
Description:CCAAT/enhancer binding protein delta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01189,008,001 - 89,008,061EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2328 AgrOrtholog
BioCyc Gene G2FUF-20545 BioCyc
Ensembl Genes ENSRNOG00000050869 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055003933 UniProtKB/Swiss-Prot
  ENSRNOG00060002893 UniProtKB/Swiss-Prot
  ENSRNOG00065008596 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074586 ENTREZGENE
  ENSRNOT00000074586.3 UniProtKB/Swiss-Prot
  ENSRNOT00055006271 UniProtKB/Swiss-Prot
  ENSRNOT00060004676 UniProtKB/Swiss-Prot
  ENSRNOT00065013653 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C/EBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C/EBP_chordates UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25695 ENTREZGENE
PANTHER CCAAT/ENHANCER BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CCAAT/ENHANCER-BINDING PROTEIN DELTA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cebpd PhenoGen
PIRSF CCAAT/enhancer-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050869 RatGTEx
  ENSRNOG00055003933 RatGTEx
  ENSRNOG00060002893 RatGTEx
  ENSRNOG00065008596 RatGTEx
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Leucine zipper domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC216969
UniProt A6JSR2 ENTREZGENE, UniProtKB/TrEMBL
  CEBPD_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Cebpd  CCAAT/enhancer binding protein delta  Cebpd  CCAAT/enhancer binding protein (C/EBP), delta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cebpd  CCAAT/enhancer binding protein (C/EBP), delta    CCAAT/enhancerbinding, protein (C/EBP) delta  Name updated 1299863 APPROVED
2002-06-10 Cebpd  CCAAT/enhancerbinding, protein (C/EBP) delta      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_drugs treatment with glucocorticoid receptor antagonist RU-38486 inhibits the sepsis-induced activation in the skeletal muscles 625506
gene_expression sepsis upregulates the DNA-binding activity of the CEBP resulting in activation 625506
gene_expression expressed in the skeletal muscle  
gene_process constitutive transcriptional activator 69805
gene_process may mediate glucose-mediated regulation of inducible nitric oxide synthase (iNOS) transcription 1298754
gene_process may be involved in regulation of lipogenic enzyme expression induced by keratinocyte growth factor (KGF) in alveolar type II cells 704418
gene_product member of the C/EBP family of transcription factors 625506
gene_product member of the C/EBP family of trancription factors 625506
gene_regulation expressed in the skeletal muscle 625506
gene_regulation expression upregulated by sepsis that is induced by cecal ligation and puncture 625506
gene_regulation mRNA and protein levels in alveolar type II cells upregulated by treatment with keratinocyte growth factor (KGF) 704418