(+)-isolariciresinol decreases expression ISO HNF1A (Homo sapiens) 6480464 isolariciresinol results in decreased expression of HNF1A mRNA CTD PMID:35755389 1,2-dimethylhydrazine decreases expression ISO Hnf1a (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of HNF1A mRNA CTD PMID:22206623 17alpha-ethynylestradiol increases expression ISO Hnf1a (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of HNF1A mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression ISO Hnf1a (Mus musculus) 6480464 Ethinyl Estradiol results in decreased expression of HNF1A mRNA and Ethinyl Estradiol results in decreased expression of HNF1A protein CTD PMID:27818225 17alpha-ethynylestradiol multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HNF1A mRNA more ... CTD PMID:17942748 and PMID:27818225 17alpha-ethynylestradiol decreases activity EXP 6480464 Ethinyl Estradiol results in decreased activity of HNF1A protein CTD PMID:12507762 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of HNF1A mRNA CTD PMID:22946080 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Hnf1a (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Hnf1a (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Hnf1a (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of HNF1A mRNA CTD PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Hnf1a (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of HNF1A mRNA CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PTCD1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HNF1A mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HNF1A gene] CTD PMID:17942748 and PMID:28213091 2,4-dinitrotoluene affects expression EXP 6480464 2 more ... CTD PMID:21346803 2,6-di-tert-butyl-4-methylphenol multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Butylated Hydroxytoluene co-treated with Oxygen] results in increased expression of HNF1A mRNA CTD PMID:16272459 5-aza-2'-deoxycytidine multiple interactions ISO HNF1A (Homo sapiens) 6480464 HNF1A protein promotes the reaction [Decitabine results in increased expression of UGT1A1 mRNA] CTD PMID:23401472 5-azacytidine decreases methylation ISO HNF1A (Homo sapiens) 6480464 Azacitidine results in decreased methylation of HNF1A promoter CTD PMID:25953102 5-azacytidine increases expression ISO HNF1A (Homo sapiens) 6480464 Azacitidine results in increased expression of HNF1A mRNA and Azacitidine results in increased expression of HNF1A protein CTD PMID:25953102 5-azacytidine multiple interactions ISO HNF1A (Homo sapiens) 6480464 HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA] CTD PMID:25953102 5-fluorouracil affects expression ISO HNF1A (Homo sapiens) 6480464 Fluorouracil affects the expression of HNF1A mRNA CTD PMID:34151400 acetylsalicylic acid decreases expression EXP 6480464 Aspirin results in decreased expression of HNF1A mRNA CTD PMID:12800193 aflatoxin B1 decreases expression ISO HNF1A (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of HNF1A mRNA CTD PMID:22100608 aflatoxin B1 decreases methylation ISO HNF1A (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of HNF1A exon CTD PMID:30157460 aldehydo-D-glucose affects response to substance ISO HNF1A (Homo sapiens) 6480464 HNF1A gene mutant form affects the susceptibility to Glucose CTD PMID:15787664 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HNF1A mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of HNF1A mRNA CTD PMID:30779732 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO HNF1A (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Acetaminophen results in decreased expression of HNF1A mRNA] and pyrazolanthrone inhibits the reaction [Acetaminophen results in decreased expression of HNF1A protein] CTD PMID:33959992 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of HNF1A mRNA CTD PMID:11163329 baicalin decreases expression ISO Hnf1a (Mus musculus) 6480464 baicalin results in decreased expression of HNF1A protein CTD PMID:32687838 baicalin decreases expression ISO HNF1A (Homo sapiens) 6480464 baicalin results in decreased expression of HNF1A mRNA and baicalin results in decreased expression of HNF1A protein CTD PMID:32687838 baicalin multiple interactions ISO HNF1A (Homo sapiens) 6480464 baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter] more ... CTD PMID:32687838 benzo[a]pyrene decreases methylation ISO HNF1A (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of HNF1A exon CTD PMID:27901495 benzo[a]pyrene decreases expression ISO HNF1A (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of HNF1A mRNA CTD PMID:32234424 benzo[a]pyrene affects methylation ISO HNF1A (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of HNF1A promoter CTD PMID:27901495 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of HNF1A mRNA and Diethylhexyl Phthalate results in decreased expression of HNF1A protein CTD PMID:15728792 and PMID:30597186 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 Diethylhexyl Phthalate promotes the reaction [HNF1A protein binds to SLC2A2 promoter] CTD PMID:30597186 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PTCD1 mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of HNF1A mRNA and bisphenol A results in increased expression of PTCD1 mRNA CTD PMID:30816183 more ... bisphenol A increases expression ISO Hnf1a (Mus musculus) 6480464 bisphenol A results in increased expression of HNF1A mRNA CTD PMID:29161229 and PMID:34585602 bisphenol A affects methylation ISO Hnf1a (Mus musculus) 6480464 bisphenol A affects the methylation of HNF1A promoter CTD PMID:27334623 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HNF1A mRNA CTD PMID:22946080 and PMID:25181051 butanal decreases expression ISO HNF1A (Homo sapiens) 6480464 butyraldehyde results in decreased expression of HNF1A mRNA CTD PMID:26079696 Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of HNF1A mRNA CTD PMID:15728792 butyric acid affects expression EXP 6480464 Butyric Acid affects the expression of HNF1A mRNA CTD PMID:12800193 caffeine affects phosphorylation ISO HNF1A (Homo sapiens) 6480464 Caffeine affects the phosphorylation of HNF1A protein CTD PMID:35688186 cannabidiol affects methylation EXP 6480464 Cannabidiol affects the methylation of HNF1A gene CTD PMID:30521419 carbamazepine affects expression ISO HNF1A (Homo sapiens) 6480464 Carbamazepine affects the expression of HNF1A mRNA CTD PMID:24752500 carmustine decreases expression ISO HNF1A (Homo sapiens) 6480464 Carmustine results in decreased expression of HNF1A mRNA CTD PMID:15980968 cisplatin decreases expression EXP 6480464 [Cisplatin results in decreased expression of HNF1A mRNA] which results in decreased expression of SLC5A1 mRNA more ... CTD PMID:18656965 cisplatin decreases expression ISO HNF1A (Homo sapiens) 6480464 Cisplatin results in decreased expression of HNF1A mRNA CTD PMID:27392435 cisplatin multiple interactions EXP 6480464 HNF1A protein affects the reaction [Cisplatin results in decreased expression of CLTRN mRNA] CTD PMID:18656965 D-glucose affects response to substance ISO HNF1A (Homo sapiens) 6480464 HNF1A gene mutant form affects the susceptibility to Glucose CTD PMID:15787664 DDT multiple interactions EXP 6480464 [DDT co-treated with Diethylnitrosamine] results in decreased expression of HNF1A mRNA and [DDT co-treated with Diethylnitrosamine] results in increased expression of HNF1A mRNA CTD PMID:15885732 dexamethasone multiple interactions ISO HNF1A (Homo sapiens) 6480464 [Ursodeoxycholic Acid co-treated with Dexamethasone] promotes the reaction [EP300 protein binds to NR3C1 protein binds to HNF1A protein binds to SLC4A2 promoter alternative form] more ... CTD PMID:18188457 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of HNF1A mRNA CTD PMID:20888898 dextran sulfate increases expression ISO Hnf1a (Mus musculus) 6480464 Dextran Sulfate results in increased expression of HNF1A protein CTD PMID:29680209 dextran sulfate multiple interactions ISO Hnf1a (Mus musculus) 6480464 6-formylindolo(3 more ... CTD PMID:29680209 and PMID:29950665 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of HNF1A mRNA CTD PMID:15728792 and PMID:21745491 diclofenac affects expression ISO HNF1A (Homo sapiens) 6480464 Diclofenac affects the expression of HNF1A mRNA CTD PMID:24752500 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of HNF1A mRNA CTD PMID:22946080 dioxygen decreases response to substance ISO HNF1A (Homo sapiens) 6480464 HNF1A gene mutant form results in decreased susceptibility to Oxygen deficiency CTD PMID:21994956 dioxygen multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Butylated Hydroxytoluene co-treated with Oxygen] results in increased expression of HNF1A mRNA CTD PMID:16272459 dipentyl phthalate decreases expression EXP 6480464 di-n-pentyl phthalate results in decreased expression of HNF1A mRNA CTD PMID:15728792 epoxiconazole decreases expression ISO Hnf1a (Mus musculus) 6480464 epoxiconazole results in decreased expression of HNF1A mRNA CTD PMID:35436446 ethanol multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of HNF1A mRNA CTD PMID:24155903 ethanol decreases expression ISO HNF1A (Homo sapiens) 6480464 Ethanol results in decreased expression of HNF1A protein CTD PMID:27989594 ethanol multiple interactions ISO HNF1A (Homo sapiens) 6480464 salvianolic acid B inhibits the reaction [Ethanol results in decreased expression of HNF1A protein] CTD PMID:27989594 folic acid increases expression ISO Hnf1a (Mus musculus) 6480464 Folic Acid results in increased expression of HNF1A mRNA CTD PMID:25629700 genistein decreases expression ISO Hnf1a (Mus musculus) 6480464 Genistein results in decreased expression of HNF1A mRNA CTD PMID:32186404 gentamycin decreases expression EXP 6480464 [Gentamicins results in decreased expression of HNF1A mRNA] which results in decreased expression of SLC5A1 mRNA more ... CTD PMID:18656965 and PMID:33387578 gentamycin multiple interactions EXP 6480464 HNF1A protein affects the reaction [Gentamicins results in decreased expression of CLTRN mRNA] CTD PMID:18656965 glucose affects response to substance ISO HNF1A (Homo sapiens) 6480464 HNF1A gene mutant form affects the susceptibility to Glucose CTD PMID:15787664 lipopolysaccharide decreases expression ISO Hnf1a (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of HNF1A protein CTD PMID:16002565 lipopolysaccharide multiple interactions EXP 6480464 Lipopolysaccharides inhibits the reaction [HNF1A protein binds to ALB promoter] and Lipopolysaccharides inhibits the reaction [HNF1A protein binds to GSTA2 promoter] CTD PMID:14561216 lithocholic acid decreases expression EXP 6480464 Lithocholic Acid results in decreased expression of HNF1A mRNA CTD PMID:20888898 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [HNF1A protein results in increased expression of IL1B mRNA] CTD PMID:15350541 mercury atom increases expression ISO HNF1A (Homo sapiens) 6480464 Mercury results in increased expression of HNF1A mRNA CTD PMID:16823088 mercury(0) increases expression ISO HNF1A (Homo sapiens) 6480464 Mercury results in increased expression of HNF1A mRNA CTD PMID:16823088 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of HNF1A mRNA CTD PMID:28013212 methidathion increases expression ISO Hnf1a (Mus musculus) 6480464 methidathion results in increased expression of HNF1A mRNA CTD PMID:34813904 N-acetylsphingosine multiple interactions EXP 6480464 N-acetylsphingosine results in decreased expression of and results in decreased activity of HNF1A protein CTD PMID:15155840 N-acetylsphingosine multiple interactions ISO HNF1A (Homo sapiens) 6480464 N-acetylsphingosine promotes the reaction [Acetaminophen results in decreased expression of HNF1A mRNA] and N-acetylsphingosine promotes the reaction [Acetaminophen results in decreased expression of HNF1A protein] CTD PMID:31385618 and PMID:33959992 N-acetylsphingosine decreases ubiquitination EXP 6480464 N-acetylsphingosine results in decreased ubiquitination of HNF1A protein CTD PMID:15155840 N-nitrosodiethylamine multiple interactions EXP 6480464 [DDT co-treated with Diethylnitrosamine] results in decreased expression of HNF1A mRNA and [DDT co-treated with Diethylnitrosamine] results in increased expression of HNF1A mRNA CTD PMID:15885732 Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of HNF1A mRNA CTD PMID:22946080 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of HNF1A mRNA CTD PMID:23358140 oleanolic acid multiple interactions ISO Hnf1a (Mus musculus) 6480464 HNF1A protein affects the reaction [SRT1720 inhibits the reaction [Oleanolic Acid results in decreased expression of ABCB11 protein]] more ... CTD PMID:37028458 oltipraz multiple interactions ISO HNF1A (Homo sapiens) 6480464 oltipraz inhibits the reaction [Acetaminophen results in decreased expression of HNF1A mRNA] and oltipraz inhibits the reaction [Acetaminophen results in decreased expression of HNF1A protein] CTD PMID:31385618 and PMID:33959992 ozone increases expression EXP 6480464 Ozone results in increased expression of HNF1A mRNA CTD PMID:35737395 paracetamol decreases activity EXP 6480464 Acetaminophen results in decreased activity of HNF1A protein CTD PMID:25858767 paracetamol multiple interactions ISO HNF1A (Homo sapiens) 6480464 N-acetylsphingosine promotes the reaction [Acetaminophen results in decreased expression of HNF1A mRNA] more ... CTD PMID:31385618 and PMID:33959992 paracetamol decreases expression ISO HNF1A (Homo sapiens) 6480464 Acetaminophen results in decreased expression of HNF1A mRNA and Acetaminophen results in decreased expression of HNF1A protein CTD PMID:29067470 more ... PCB138 multiple interactions ISO Hnf1a (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 perfluorooctanoic acid multiple interactions ISO HNF1A (Homo sapiens) 6480464 [perfluorooctanoic acid results in decreased activity of HNF4A protein] which results in decreased expression of HNF1A mRNA CTD PMID:22609092 perfluorooctanoic acid decreases expression ISO HNF1A (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of HNF1A mRNA and perfluorooctanoic acid results in decreased expression of HNF1A protein CTD PMID:22609092 and PMID:25868421 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of HNF1A mRNA CTD PMID:20888898 propanal decreases expression ISO HNF1A (Homo sapiens) 6480464 propionaldehyde results in decreased expression of HNF1A mRNA CTD PMID:26079696 prothioconazole decreases expression ISO HNF1A (Homo sapiens) 6480464 prothioconazole results in decreased expression of HNF1A mRNA CTD PMID:35048155 Ptaquiloside decreases expression ISO Hnf1a (Mus musculus) 6480464 ptaquiloside results in decreased expression of HNF1A mRNA CTD PMID:23274088 resveratrol increases expression ISO HNF1A (Homo sapiens) 6480464 resveratrol results in increased expression of HNF1A mRNA CTD PMID:21163946 salvianolic acid B multiple interactions ISO HNF1A (Homo sapiens) 6480464 salvianolic acid B inhibits the reaction [Ethanol results in decreased expression of HNF1A protein] CTD PMID:27989594 senecionine decreases expression ISO Hnf1a (Mus musculus) 6480464 senecionine results in decreased expression of HNF1A protein CTD PMID:35357534 silicon dioxide decreases expression ISO HNF1A (Homo sapiens) 6480464 Silicon Dioxide results in decreased expression of HNF1A mRNA CTD PMID:23623845 simvastatin increases expression ISO Hnf1a (Mus musculus) 6480464 Simvastatin results in increased expression of HNF1A mRNA CTD PMID:22160096 sodium arsenite decreases expression ISO HNF1A (Homo sapiens) 6480464 sodium arsenite results in decreased expression of HNF1A mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO Hnf1a (Mus musculus) 6480464 sodium arsenite results in decreased expression of HNF1A mRNA CTD PMID:37682722 sodium arsenite multiple interactions ISO HNF1A (Homo sapiens) 6480464 sodium arsenite promotes the reaction [HNF1A protein binds to CAPRIN1 protein] CTD PMID:33939924 testosterone decreases expression ISO HNF1A (Homo sapiens) 6480464 Testosterone results in decreased expression of HNF1A mRNA CTD PMID:33359661 tetrachloromethane increases expression ISO Hnf1a (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of HNF1A mRNA CTD PMID:15056808 tetrachloromethane decreases activity EXP 6480464 Carbon Tetrachloride results in decreased activity of HNF1A protein CTD PMID:25858767 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of HNF1A mRNA CTD PMID:34492290 thymoquinone decreases expression ISO HNF1A (Homo sapiens) 6480464 thymoquinone results in decreased expression of HNF1A mRNA CTD PMID:32112862 titanium dioxide multiple interactions ISO Hnf1a (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HNF1A mRNA CTD PMID:29950665 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of HNF1A mRNA CTD PMID:33387578 trimellitic anhydride decreases expression ISO Hnf1a (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of HNF1A mRNA CTD PMID:19042947 triptonide increases expression ISO Hnf1a (Mus musculus) 6480464 triptonide results in increased expression of HNF1A mRNA CTD PMID:33045310 urethane decreases expression ISO HNF1A (Homo sapiens) 6480464 Urethane results in decreased expression of HNF1A mRNA CTD PMID:28818685 ursodeoxycholic acid multiple interactions ISO HNF1A (Homo sapiens) 6480464 [Ursodeoxycholic Acid co-treated with Dexamethasone] promotes the reaction [EP300 protein binds to NR3C1 protein binds to HNF1A protein binds to SLC4A2 promoter alternative form] more ... CTD PMID:18188457 valproic acid affects expression ISO Hnf1a (Mus musculus) 6480464 Valproic Acid affects the expression of HNF1A mRNA CTD PMID:17963808 valproic acid decreases expression ISO HNF1A (Homo sapiens) 6480464 Valproic Acid results in decreased expression of HNF1A mRNA CTD PMID:29154799 zinc atom affects expression ISO Hnf1a (Mus musculus) 6480464 Zinc deficiency affects the expression of HNF1A mRNA CTD PMID:24155903 zinc atom multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of HNF1A mRNA CTD PMID:24155903 zinc(0) affects expression ISO Hnf1a (Mus musculus) 6480464 Zinc deficiency affects the expression of HNF1A mRNA CTD PMID:24155903 zinc(0) multiple interactions ISO Hnf1a (Mus musculus) 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of HNF1A mRNA CTD PMID:24155903