| 1,3-dinitrobenzene | decreases expression | EXP | | 6480464 | 3-dinitrobenzene results in decreased expression of PLK1 mRNA | CTD | PMID:22841810 |
| 17beta-estradiol | multiple interactions | ISO | RGD:1353801 | 6480464 | fulvestrant inhibits the reaction [Estradiol results in increased expression of PLK1 protein]; more ... | CTD | PMID:20208560 |
| 17beta-estradiol | affects expression | ISO | RGD:11121 | 6480464 | Estradiol affects the expression of PLK1 mRNA | CTD | PMID:15598610 |
| 17beta-estradiol | increases expression | ISO | RGD:1353801 | 6480464 | Estradiol results in increased expression of PLK1 protein | CTD | PMID:20208560 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:11121 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PLK1 mRNA | CTD | PMID:15667827 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:11121 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PLK1 mRNA | CTD | PMID:21570461 |
| 2,3-dimethoxynaphthalene-1,4-dione | increases expression | ISO | RGD:1353801 | 6480464 | 2,3-dimethoxy-1,4-naphthoquinone results in increased expression of PLK1 mRNA | CTD | PMID:19031421 |
| 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of PLK1 mRNA | CTD | PMID:21346803 |
| 2-amino-2-deoxy-D-glucopyranose | increases expression | ISO | RGD:11121 | 6480464 | Glucosamine results in increased expression of PLK1 mRNA | CTD | PMID:17178593 |
| 2-amino-2-deoxy-D-glucopyranose | decreases expression | EXP | | 6480464 | Glucosamine results in decreased expression of PLK1 mRNA | CTD | PMID:17109745 |
| 2-methoxyethanol | decreases expression | EXP | | 6480464 | methyl cellosolve results in decreased expression of PLK1 mRNA | CTD | PMID:9681501 |
| 4-hydroxynon-2-enal | decreases expression | ISO | RGD:11121 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of PLK1 mRNA | CTD | PMID:19191707 |
| 5-fluorouracil | increases expression | ISO | RGD:1353801 | 6480464 | Fluorouracil results in increased expression of PLK1 protein | CTD | PMID:15016801 |
| 5-fluorouracil | decreases expression | ISO | RGD:1353801 | 6480464 | Fluorouracil results in decreased expression of PLK1 mRNA | CTD | PMID:15205334 |
| 5-fluorouracil | multiple interactions | ISO | RGD:1353801 | 6480464 | TP53 protein affects the reaction [Fluorouracil results in decreased expression of PLK1 mRNA]; more ... | CTD | PMID:15016801 |
| aldehydo-D-glucosamine | increases expression | ISO | RGD:11121 | 6480464 | Glucosamine results in increased expression of PLK1 mRNA | CTD | PMID:17178593 |
| aldehydo-D-glucosamine | decreases expression | EXP | | 6480464 | Glucosamine results in decreased expression of PLK1 mRNA | CTD | PMID:17109745 |
| all-trans-retinoic acid | decreases expression | ISO | RGD:1353801 | 6480464 | Tretinoin results in decreased expression of PLK1 mRNA | CTD | PMID:16249480 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PLK1 mRNA | CTD | PMID:16483693 |
| arsenite(3-) | decreases expression | ISO | RGD:11121 | 6480464 | arsenite results in decreased expression of PLK1 mRNA | CTD | PMID:18929588 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1353801 | 6480464 | Benzo(a)pyrene results in decreased expression of PLK1 mRNA | CTD | PMID:20106945 PMID:20064835 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1353801 | 6480464 | Benzo(a)pyrene results in decreased expression of PLK1 mRNA | CTD | PMID:20064835 more ... |
| benzo[a]pyrene | decreases expression | ISO | RGD:1353801 | 6480464 | Benzo(a)pyrene results in decreased expression of PLK1 mRNA | CTD | PMID:20064835 more ... |
| benzo[a]pyrene | decreases expression | ISO | RGD:1353801 | 6480464 | Benzo(a)pyrene results in decreased expression of PLK1 mRNA | CTD | PMID:20064835 PMID:20106945 |
| beta-D-glucosamine | increases expression | ISO | RGD:11121 | 6480464 | Glucosamine results in increased expression of PLK1 mRNA | CTD | PMID:17178593 |
| beta-D-glucosamine | decreases expression | EXP | | 6480464 | Glucosamine results in decreased expression of PLK1 mRNA | CTD | PMID:17109745 |
| calcitriol | multiple interactions | ISO | RGD:1353801 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of PLK1 mRNA | CTD | PMID:21592394 |
| calcitriol | decreases expression | ISO | RGD:1353801 | 6480464 | Calcitriol results in decreased expression of PLK1 mRNA | CTD | PMID:21592394 |
| cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of PLK1 mRNA | CTD | PMID:18500788 |
| choline | multiple interactions | ISO | RGD:11121 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PLK1 mRNA | CTD | PMID:20938992 |
| ciprofloxacin | increases expression | EXP | | 6480464 | Ciprofloxacin results in increased expression of PLK1 protein | CTD | PMID:18512786 |
| cis-caffeic acid | multiple interactions | ISO | RGD:1353801 | 6480464 | [Thapsigargin co-treated with caffeic acid] results in increased expression of PLK1 mRNA | CTD | PMID:19442820 |
| cisplatin | increases localization | ISO | RGD:1353801 | 6480464 | Cisplatin results in increased localization of PLK1 protein | CTD | PMID:20655883 |
| cisplatin | decreases response to substance | ISO | RGD:11121 | 6480464 | PLK1 results in decreased susceptibility to Cisplatin | CTD | PMID:22006019 |
| cisplatin | increases expression | ISO | RGD:11121 | 6480464 | Cisplatin results in increased expression of PLK1 mRNA | CTD | PMID:21151649 |
| cisplatin | decreases response to substance | ISO | RGD:1353801 | 6480464 | PLK1 results in decreased susceptibility to Cisplatin | CTD | PMID:22000864 |
| cisplatin | decreases response to substance | ISO | RGD:1353801 | 6480464 | PLK1 protein results in decreased susceptibility to Cisplatin | CTD | PMID:20655883 |
| cisplatin | multiple interactions | ISO | RGD:1353801 | 6480464 | Cisplatin results in increased localization of [PLK1 protein co-treated with TP73 protein]; more ... | CTD | PMID:20655883 |
| clofibrate | decreases expression | ISO | RGD:11121 | 6480464 | Clofibrate results in decreased expression of PLK1 mRNA | CTD | PMID:17585979 |
| clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of PLK1 mRNA | CTD | PMID:15033592 |
| cobalt dichloride | decreases expression | ISO | RGD:1353801 | 6480464 | cobaltous chloride results in decreased expression of PLK1 mRNA | CTD | PMID:19376846 PMID:19320972 |
| cobalt dichloride | decreases expression | ISO | RGD:1353801 | 6480464 | cobaltous chloride results in decreased expression of PLK1 mRNA | CTD | PMID:19320972 PMID:19376846 |
| copper atom | multiple interactions | ISO | RGD:1353801 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PLK1 mRNA | CTD | PMID:20971185 |
| copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of PLK1 mRNA | CTD | PMID:22465980 |
| copper(0) | multiple interactions | ISO | RGD:1353801 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PLK1 mRNA | CTD | PMID:20971185 |
| copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of PLK1 mRNA | CTD | PMID:22465980 |
| copper(2+) sulfate | decreases expression | ISO | RGD:1353801 | 6480464 | Copper Sulfate results in decreased expression of PLK1 mRNA | CTD | PMID:19549813 |
| corticosterone | decreases expression | EXP | | 6480464 | Corticosterone results in decreased expression of PLK1 mRNA | CTD | PMID:15755911 |
| coumestrol | multiple interactions | ISO | RGD:1353801 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of PLK1 mRNA; more ... | CTD | PMID:19167446 |
| coumestrol | increases expression | ISO | RGD:1353801 | 6480464 | Coumestrol results in increased expression of PLK1 mRNA | CTD | PMID:19167446 |
| coumestrol | multiple interactions | ISO | RGD:1353801 | 6480464 | [Coumestrol co-treated with ESR1 protein] results in increased expression of PLK1 mRNA; more ... | CTD | PMID:18310284 |
| cyclosporin A | decreases expression | ISO | RGD:1353801 | 6480464 | Cyclosporine results in decreased expression of PLK1 mRNA | CTD | PMID:20106945 |
| cyclosporin A | decreases expression | ISO | RGD:1353801 | 6480464 | Cyclosporine results in decreased expression of PLK1 mRNA | CTD | PMID:20106945 PMID:22147139 |
| cyclosporin A | decreases expression | ISO | RGD:1353801 | 6480464 | Cyclosporine results in decreased expression of PLK1 mRNA | CTD | PMID:20106945 more ... |
| D-glucose | increases expression | ISO | RGD:11121 | 6480464 | Glucose results in increased expression of PLK1 mRNA | CTD | PMID:17178593 |
| dasatinib (anhydrous) | decreases expression | ISO | RGD:1353801 | 6480464 | dasatinib results in decreased expression of PLK1 mRNA | CTD | PMID:20579391 |
| dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PLK1 mRNA | CTD | PMID:21266533 |
| dibutyl phthalate | decreases expression | ISO | RGD:11121 | 6480464 | Dibutyl Phthalate results in decreased expression of PLK1 mRNA | CTD | PMID:17361019 |
| doxorubicin | decreases expression | ISO | RGD:1353801 | 6480464 | Doxorubicin results in decreased expression of PLK1 mRNA | CTD | PMID:15205334 |
| folic acid | multiple interactions | ISO | RGD:11121 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PLK1 mRNA | CTD | PMID:20938992 |
| fulvestrant | multiple interactions | ISO | RGD:1353801 | 6480464 | fulvestrant inhibits the reaction [Estradiol results in increased expression of PLK1 protein] | CTD | PMID:20208560 |
| glucose | increases expression | ISO | RGD:11121 | 6480464 | Glucose results in increased expression of PLK1 mRNA | CTD | PMID:17178593 |
| hydrogen peroxide | decreases expression | ISO | RGD:1353801 | 6480464 | Hydrogen Peroxide results in decreased expression of PLK1 mRNA | CTD | PMID:12414654 |
| indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PLK1 mRNA | CTD | PMID:22129741 |
| L-ascorbic acid | multiple interactions | ISO | RGD:1353801 | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in increased expression of PLK1 mRNA | CTD | PMID:17639512 |
| L-methionine | multiple interactions | ISO | RGD:11121 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PLK1 mRNA | CTD | PMID:20938992 |
| lucanthone | decreases expression | ISO | RGD:1353801 | 6480464 | Lucanthone results in decreased expression of PLK1 mRNA | CTD | PMID:21148553 |
| luteolin | decreases expression | ISO | RGD:1353801 | 6480464 | Luteolin results in decreased expression of PLK1 protein | CTD | PMID:22926442 |
| menadione | decreases expression | ISO | RGD:1353801 | 6480464 | Vitamin K 3 results in decreased expression of PLK1 mRNA | CTD | PMID:12414654 |
| N-nitrosodiethylamine | increases expression | ISO | RGD:11121 | 6480464 | Diethylnitrosamine results in increased expression of PLK1 mRNA | CTD | PMID:17854601 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PLK1 mRNA | CTD | PMID:22129741 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:11121 | 6480464 | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLK1 mRNA] | CTD | PMID:17854601 |
| nickel atom | increases expression | ISO | RGD:1353801 | 6480464 | Nickel results in increased expression of PLK1 mRNA | CTD | PMID:19031421 |
| ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of PLK1 mRNA | CTD | PMID:16251485 |
| ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of PLK1 mRNA | CTD | PMID:19237604 PMID:16251485 |
| ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of PLK1 mRNA | CTD | PMID:16251485 PMID:19237604 |
| paclitaxel | multiple interactions | ISO | RGD:1353801 | 6480464 | [pifithrin co-treated with Paclitaxel] results in increased expression of PLK1 protein | CTD | PMID:18516295 |
| paracetamol | affects expression | ISO | RGD:11121 | 6480464 | Acetaminophen affects the expression of PLK1 mRNA | CTD | PMID:17562736 |
| phenobarbital | increases expression | ISO | RGD:11121 | 6480464 | Phenobarbital results in increased expression of PLK1 mRNA | CTD | PMID:20403969 |
| phorbol 13-acetate 12-myristate | increases expression | ISO | RGD:1353801 | 6480464 | Tetradecanoylphorbol Acetate results in increased expression of PLK1 mRNA | CTD | PMID:19031421 |
| pirinixic acid | increases expression | ISO | RGD:11121 | 6480464 | pirinixic acid results in increased expression of PLK1 mRNA | CTD | PMID:17950772 |
| pirinixic acid | multiple interactions | ISO | RGD:11121 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of PLK1 mRNA] | CTD | PMID:17950772 |
| pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PLK1 mRNA | CTD | PMID:19162173 |
| pirinixic acid | decreases expression | ISO | RGD:11121 | 6480464 | pirinixic acid results in decreased expression of PLK1 mRNA | CTD | PMID:17426115 |
| pregnenolone 16alpha-carbonitrile | increases expression | ISO | RGD:11121 | 6480464 | Pregnenolone Carbonitrile results in increased expression of PLK1 mRNA | CTD | PMID:22698814 |
| quercetin | multiple interactions | ISO | RGD:1353801 | 6480464 | [Quercetin co-treated with Ascorbic Acid] results in increased expression of PLK1 mRNA | CTD | PMID:17639512 |
| quercetin | decreases expression | ISO | RGD:1353801 | 6480464 | Quercetin results in decreased expression of PLK1 mRNA | CTD | PMID:21632981 |
| resveratrol | decreases expression | ISO | RGD:1353801 | 6480464 | resveratrol results in decreased expression of PLK1 mRNA | CTD | PMID:15767336 |
| resveratrol | multiple interactions | ISO | RGD:1353801 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of PLK1 mRNA | CTD | PMID:19167446 |
| silver(1+) nitrate | decreases expression | ISO | RGD:1353801 | 6480464 | Silver Nitrate analog results in decreased expression of PLK1 mRNA | CTD | PMID:22831968 |
| tamoxifen | multiple interactions | ISO | RGD:1353801 | 6480464 | Tamoxifen inhibits the reaction [Estradiol results in increased expression of PLK1 protein] | CTD | PMID:20208560 |
| tert-butyl hydroperoxide | decreases expression | ISO | RGD:1353801 | 6480464 | tert-Butylhydroperoxide results in decreased expression of PLK1 mRNA | CTD | PMID:12414654 |
| tert-butyl hydroperoxide | increases expression | ISO | RGD:11121 | 6480464 | tert-Butylhydroperoxide results in increased expression of PLK1 mRNA | CTD | PMID:15003993 |
| testosterone | multiple interactions | ISO | RGD:1353801 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of PLK1 mRNA | CTD | PMID:21592394 |
| testosterone | decreases expression | ISO | RGD:1353801 | 6480464 | Testosterone results in decreased expression of PLK1 mRNA | CTD | PMID:21592394 |
| tetrachloromethane | affects expression | ISO | RGD:11121 | 6480464 | Carbon Tetrachloride affects the expression of PLK1 mRNA | CTD | PMID:17484886 |
| tetrachloromethane | multiple interactions | ISO | RGD:11121 | 6480464 | PLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of PLK1 mRNA] | CTD | PMID:16006527 |
| thapsigargin | multiple interactions | ISO | RGD:1353801 | 6480464 | [Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in increased expression of PLK1 mRNA; more ... | CTD | PMID:19442820 |
| thapsigargin | increases expression | ISO | RGD:1353801 | 6480464 | Thapsigargin results in increased expression of PLK1 mRNA | CTD | PMID:19442820 |
| thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PLK1 mRNA | CTD | PMID:22659510 |
| titanium dioxide | affects activity | ISO | RGD:11121 | 6480464 | titanium dioxide affects the activity of PLK1 protein | CTD | PMID:19695278 |
| trans-resveratrol | decreases expression | ISO | RGD:1353801 | 6480464 | resveratrol results in decreased expression of PLK1 mRNA | CTD | PMID:15767336 |
| trans-resveratrol | multiple interactions | ISO | RGD:1353801 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of PLK1 mRNA | CTD | PMID:19167446 |
| trimellitic anhydride | increases expression | ISO | RGD:11121 | 6480464 | trimellitic anhydride results in increased expression of PLK1 mRNA | CTD | PMID:19042947 |
| troglitazone | decreases expression | ISO | RGD:1353801 | 6480464 | troglitazone results in decreased expression of PLK1 mRNA | CTD | PMID:19140230 |
| valproic acid | affects expression | ISO | RGD:11121 | 6480464 | Valproic Acid affects the expression of PLK1 mRNA | CTD | PMID:17292431 |
| zoledronic acid | decreases expression | ISO | RGD:1353801 | 6480464 | zoledronic acid results in decreased expression of PLK1 mRNA | CTD | PMID:20977926 |