Gene: Abca1 (ATP binding cassette subfamily A member 1) Rattus norvegicus
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Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Description: ENCODES a protein that exhibits ATPase activity, coupled to transmembrane movement of substances; anion transmembrane transporter activity (ortholog); apolipoprotein A-I binding (ortholog); INVOLVED IN cellular response to cholesterol; cholesterol transport; lipoprotein biosynthetic process; PARTICIPATES IN altered reverse cholesterol transport pathway; retinol metabolic pathway; reverse cholesterol transport pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; familial hyperlipidemia; Fatty Liver; FOUND IN cell surface; high-density lipoprotein particle; endocytic vesicle (ortholog); INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family A member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, subfamily A (ABC1), member 1
Orthologs:
Homo sapiens (human) : ABCA1 (ATP binding cassette subfamily A member 1)  HGNC
Mus musculus (house mouse) : Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Abca1 (ATP binding cassette subfamily A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA1 (ATP binding cassette subfamily A member 1)
Canis lupus familiaris (dog) : ABCA1 (ATP binding cassette subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abca1 (ATP binding cassette subfamily A member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0569,857,717 - 69,983,042 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0574,023,652 - 74,112,802 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4570,493,357 - 70,583,729 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1570,498,469 - 70,588,842 (-)NCBI
Celera566,575,764 - 66,665,022 (-)NCBI
Cytogenetic Map5q23-q24NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Abca1
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 631344
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE