Gene: Abca1 (ATP binding cassette subfamily A member 1) Rattus norvegicus
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Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Description: ENCODES a protein that exhibits ATPase activity, coupled to transmembrane movement of substances; anion transmembrane transporter activity (ortholog); apolipoprotein A-I binding (ortholog); INVOLVED IN cellular response to cholesterol; cholesterol transport; lipoprotein biosynthetic process; PARTICIPATES IN altered reverse cholesterol transport pathway; retinol metabolic pathway; reverse cholesterol transport pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; familial hyperlipidemia; Fatty Liver; FOUND IN cell surface; high-density lipoprotein particle; endocytic vesicle (ortholog); INTERACTS WITH (25R)-cholest-5-ene-3beta,26-diol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family A member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, subfamily A (ABC1), member 1
Orthologs:
Homo sapiens (human) : ABCA1 (ATP binding cassette subfamily A member 1)  HGNC  AGR
Mus musculus (house mouse) : Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Abca1 (ATP binding cassette subfamily A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA1 (ATP binding cassette subfamily A member 1)
Canis lupus familiaris (dog) : ABCA1 (ATP binding cassette subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abca1 (ATP binding cassette subfamily A member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0569,857,717 - 69,983,042 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0574,023,652 - 74,112,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4570,493,357 - 70,583,729 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1570,498,469 - 70,588,842 (-)NCBI
Celera566,575,764 - 66,665,022 (-)NCBICelera
Cytogenetic Map5q23-q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Abca1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631344
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2017-11-28
Status: ACTIVE