Gene: Kdr (kinase insert domain receptor) Rattus norvegicus
Symbol: Kdr
Name: kinase insert domain receptor
Description: ENCODES a protein that exhibits growth factor binding; vascular endothelial growth factor-activated receptor activity; integrin binding (ortholog); INVOLVED IN aging; endochondral bone growth; hyaluronan metabolic process; PARTICIPATES IN altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression; altered vascular endothelial growth factor signaling pathway involving the main players; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH abnormal depression-related behavior; abnormal passive avoidance behavior; abnormal retinal vasculature morphology; ASSOCIATED WITH Acute Lung Injury; Arteriosclerosis; Brain Injuries; FOUND IN cytoplasm; neuron projection; neuronal cell body; INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
Also known as: fetal liver kinase 1; FLK-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); kinase insert domain protein receptor; MGC93590; protein-tyrosine kinase receptor flk-1; vascular endothelial growth factor receptor 2; Vegfr-2
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01434,727,677 - 34,787,127 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01434,557,361 - 34,618,112 (+)NCBIRnor5.0rn5Rnor5.0
Celera1431,512,534 - 31,554,989 (+)NCBI
Cytogenetic Map14p11NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kdr
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2965
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-11
Status: ACTIVE