Gene: Lcat (lecithin cholesterol acyltransferase) Rattus norvegicus
Symbol: Lcat
Name: lecithin cholesterol acyltransferase
Description: ENCODES a protein that exhibits phosphatidylcholine-sterol O-acyltransferase activity; phospholipase A2 activity; apolipoprotein A-I binding (ortholog); INVOLVED IN cholesterol metabolic process; lipoprotein metabolic process; response to copper ion; PARTICIPATES IN reverse cholesterol transport pathway; glycerophospholipid metabolic pathway; ASSOCIATED WITH Hyperlipidemias; Kidney Failure, Chronic; Myocardial Infarction; FOUND IN extracellular exosome (ortholog); extracellular space (ortholog); high-density lipoprotein particle (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Lecithin-cholesterol acyltransferase; MGC108718; phosphatidylcholine-sterol acyltransferase; phospholipid-cholesterol acyltransferase
Orthologs:
Allele / Splice: Lcatm1Mcwi   Lcatm2Mcwi   Lcatm3Mcwi   Lcatm4Mcwi   Lcatm5Mcwi  
Is Marker For: QTLs:   Insglur2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01937,913,333 - 37,916,799 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01948,780,364 - 48,783,830 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41935,781,507 - 35,784,966 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11935,786,383 - 35,789,855 (-)NCBI
Celera1933,262,304 - 33,265,763 (-)NCBI
Cytogenetic Map19q12NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lcat
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2993
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE