Gene: Lcat (lecithin cholesterol acyltransferase) Rattus norvegicus
Symbol: Lcat
Name: lecithin cholesterol acyltransferase
Description: ENCODES a protein that exhibits phosphatidylcholine-sterol O-acyltransferase activity; phospholipase A2 activity; apolipoprotein A-I binding (ortholog); INVOLVED IN cholesterol metabolic process; lipoprotein metabolic process; response to copper ion; PARTICIPATES IN reverse cholesterol transport pathway; glycerophospholipid metabolic pathway; ASSOCIATED WITH Hyperlipidemias; Kidney Failure, Chronic; Myocardial Infarction; FOUND IN extracellular space (ortholog); extracellular vesicular exosome (ortholog); high-density lipoprotein particle (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Lecithin-cholesterol acyltransferase; MGC108718; phosphatidylcholine-sterol acyltransferase; phospholipid-cholesterol acyltransferase
Orthologs:
Allele / Splice: Lcatm1Mcwi   Lcatm2Mcwi   Lcatm3Mcwi   Lcatm4Mcwi   Lcatm5Mcwi  
Is Marker For: QTLs:   Insglur2  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.01937,913,333 - 37,916,799-NCBI
Rat Cytogenetic Map19q12 NCBI
RGSC Genome Assembly v5.01948,780,364 - 48,783,830-NCBI
RGSC Genome Assembly v3.41935,781,507 - 35,784,966-NCBI
Rat Celera Assembly1933,262,304 - 33,265,763-NCBI
Genome Assembly 3.11935,786,383 - 35,789,855-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lcat
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2993
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-10-21
Status: ACTIVE