| (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one | increases degradation | ISO | RGD:1316062 | 6480464 | cyclopiazonic acid results in increased degradation of TP73 protein modified form | CTD | PMID:21516125 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1316063 | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRP73 mRNA | CTD | PMID:21570461 |
| 4-hydroxynon-2-enal | increases expression | ISO | RGD:1316062 | 6480464 | 4-hydroxy-2-nonenal results in increased expression of TP73 protein | CTD | PMID:15607904 |
| 5-aza-2'-deoxycytidine | decreases methylation | ISO | RGD:1316062 | 6480464 | decitabine results in decreased methylation of TP73 promoter | CTD | PMID:19194470 |
| 5-azacytidine | multiple interactions | ISO | RGD:1316062 | 6480464 | TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]; more ... | CTD | PMID:21245298 |
| 5-fluorouracil | affects response to substance | ISO | RGD:1316062 | 6480464 | TP73 protein affects the susceptibility to Fluorouracil | CTD | PMID:18714155 |
| 5-fluorouracil | multiple interactions | ISO | RGD:1316062 | 6480464 | TP73 protein promotes the reaction [Fluorouracil results in increased expression of GRAMD4 mRNA] | CTD | PMID:21127500 |
| apigenin | increases expression | ISO | RGD:1316062 | 6480464 | Apigenin results in increased expression of TP73 protein | CTD | PMID:19397994 |
| benzo[a]pyrene | increases expression | ISO | RGD:1316062 | 6480464 | Benzo(a)pyrene results in increased expression of TP73 mRNA | CTD | PMID:20862736 |
| benzo[a]pyrene | affects activity | ISO | RGD:1316062 | 6480464 | Benzo(a)pyrene affects the activity of TP73 protein | CTD | PMID:20624995 |
| calcitriol | multiple interactions | ISO | RGD:1316062 | 6480464 | [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol | CTD | PMID:17716971 |
| calcium atom | multiple interactions | ISO | RGD:1316062 | 6480464 | [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form | CTD | PMID:21516125 |
| calcium(0) | multiple interactions | ISO | RGD:1316062 | 6480464 | [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form | CTD | PMID:21516125 |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | [Sirolimus co-treated with Cisplatin] results in increased expression of TP73 protein; more ... | CTD | PMID:20686837 |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:17076661 more ... |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:17076661 more ... |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:21274007 more ... |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | [Cisplatin co-treated with TP73 protein] results in increased expression of BAX protein; more ... | CTD | PMID:20100536 |
| cisplatin | increases response to substance | ISO | RGD:1316062 | 6480464 | TP73 results in increased susceptibility to Cisplatin | CTD | PMID:20100536 |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:21274007 more ... |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:21214929 more ... |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:21214929 more ... |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | RELA protein mutant form inhibits the reaction [Cisplatin results in decreased expression of TP73 mRNA]; more ... | CTD | PMID:21737676 |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased localization of [PLK1 protein co-treated with TP73 protein]; more ... | CTD | PMID:20655883 |
| cisplatin | increases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased expression of TP73 protein | CTD | PMID:21274007 more ... |
| cisplatin | increases activity | ISO | RGD:1316062 | 6480464 | Cisplatin results in increased activity of TP73 protein | CTD | PMID:14678968 |
| cisplatin | decreases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in decreased expression of TP73 protein modified form | CTD | PMID:21516125 |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | Cisplatin promotes the reaction [[TP73 protein binds to GRAMD4 promoter] which results in increased expression of GRAMD4 mRNA]; more ... | CTD | PMID:21127500 |
| cisplatin | decreases expression | ISO | RGD:1316062 | 6480464 | Cisplatin results in decreased expression of TP73 mRNA | CTD | PMID:21737676 |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | Cisplatin promotes the reaction [[TP73 protein binds to IL4R intron] which results in increased expression of IL4R mRNA] | CTD | PMID:14678968 |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | [[Cisplatin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased expression of TP73 protein] which results in decreased expression of BCL2 mRNA; more ... | CTD | PMID:21214929 |
| cisplatin | affects localization | ISO | RGD:1316062 | 6480464 | Cisplatin affects the localization of TP73 protein modified form | CTD | PMID:21516125 |
| cisplatin | multiple interactions | ISO | RGD:1316062 | 6480464 | calpeptin inhibits the reaction [Cisplatin results in decreased expression of TP73 protein modified form]; more ... | CTD | PMID:21516125 |
| cisplatin | increases expression | ISO | RGD:1316063 | 6480464 | Cisplatin results in increased expression of TRP73 | CTD | PMID:22002055 |
| cisplatin | decreases response to substance | ISO | RGD:1316063 | 6480464 | TRP73 alternative form results in decreased susceptibility to Cisplatin | CTD | PMID:22002055 |
| cisplatin | decreases expression | ISO | RGD:1316063 | 6480464 | Cisplatin results in decreased expression of TRP73 alternative form | CTD | PMID:22002055 |
| cisplatin | increases response to substance | ISO | RGD:1316062 | 6480464 | TP73 protein modified form results in increased susceptibility to Cisplatin | CTD | PMID:21516125 |
| copper atom | decreases expression | ISO | RGD:1316062 | 6480464 | Copper results in decreased expression of TP73 mRNA | CTD | PMID:16391388 |
| copper(0) | decreases expression | ISO | RGD:1316062 | 6480464 | Copper results in decreased expression of TP73 mRNA | CTD | PMID:16391388 |
| diarsenic trioxide | multiple interactions | ISO | RGD:1316062 | 6480464 | 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [arsenic trioxide results in increased expression of TP73 protein alternative form] | CTD | PMID:16467208 |
| diarsenic trioxide | increases expression | ISO | RGD:1316062 | 6480464 | arsenic trioxide results in increased expression of TP73 mRNA | CTD | PMID:20458559 PMID:19763917 |
| diarsenic trioxide | increases expression | ISO | RGD:1316062 | 6480464 | arsenic trioxide results in increased expression of TP73 mRNA | CTD | PMID:19763917 PMID:20458559 |
| diarsenic trioxide | multiple interactions | ISO | RGD:1316062 | 6480464 | [arsenic trioxide co-treated with PD 98059] promotes the reaction [TP73 protein binds to TP53AIP1 promoter]; more ... | CTD | PMID:15031205 |
| doxorubicin | multiple interactions | ISO | RGD:1316062 | 6480464 | [[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased expression of TP73 protein] which results in decreased expression of BCL2 mRNA; more ... | CTD | PMID:21214929 |
| doxorubicin | increases expression | ISO | RGD:1316062 | 6480464 | Doxorubicin results in increased expression of TP73 protein | CTD | PMID:21214929 PMID:17716971 |
| doxorubicin | increases expression | ISO | RGD:1316062 | 6480464 | Doxorubicin results in increased expression of TP73 protein | CTD | PMID:17716971 PMID:21214929 |
| doxorubicin | increases expression | ISO | RGD:1316062 | 6480464 | Doxorubicin results in increased expression of TP73 mRNA | CTD | PMID:17716971 |
| etoposide | increases expression | ISO | RGD:1316062 | 6480464 | Etoposide results in increased expression of TP73 mRNA | CTD | PMID:17716971 |
| etoposide | increases expression | ISO | RGD:1316062 | 6480464 | Etoposide results in increased expression of TP73 protein | CTD | PMID:17716971 PMID:21801448 |
| etoposide | multiple interactions | ISO | RGD:1316062 | 6480464 | TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; more ... | CTD | PMID:21801448 |
| etoposide | multiple interactions | ISO | RGD:1316062 | 6480464 | [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; more ... | CTD | PMID:17716971 |
| etoposide | increases expression | ISO | RGD:1316062 | 6480464 | Etoposide results in increased expression of TP73 protein | CTD | PMID:21801448 PMID:17716971 |
| kaempferol | increases expression | ISO | RGD:1316062 | 6480464 | kaempferol results in increased expression of TP73 protein | CTD | PMID:19397994 PMID:18331776 |
| kaempferol | increases expression | ISO | RGD:1316062 | 6480464 | kaempferol results in increased expression of TP73 protein | CTD | PMID:18331776 PMID:19397994 |
| luteolin | increases expression | ISO | RGD:1316062 | 6480464 | Luteolin results in increased expression of TP73 protein | CTD | PMID:18331776 PMID:19397994 |
| luteolin | increases expression | ISO | RGD:1316062 | 6480464 | Luteolin results in increased expression of TP73 protein | CTD | PMID:19397994 PMID:18331776 |
| mitomycin C | increases expression | ISO | RGD:1316062 | 6480464 | Mitomycin results in increased expression of TRP73 protein | CTD | PMID:17530733 |
| mitomycin C | multiple interactions | ISO | RGD:1316062 | 6480464 | TRP53 protein affects the reaction [Mitomycin results in increased expression of TRP73 protein] | CTD | PMID:17530733 |
| myricetin | increases expression | ISO | RGD:1316062 | 6480464 | myricetin results in increased expression of TP73 protein | CTD | PMID:19397994 |
| N-methyl-4-phenylpyridinium | multiple interactions | ISO | RGD:1316062 | 6480464 | U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of TP73 mRNA] | CTD | PMID:12710931 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1316063 | 6480464 | AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TRP73 mRNA] | CTD | PMID:19996281 |
| N-nitrosodiethylamine | decreases expression | ISO | RGD:1316063 | 6480464 | Diethylnitrosamine results in decreased expression of TRP73 mRNA | CTD | PMID:19996281 |
| nickel dichloride | increases phosphorylation | ISO | RGD:1316062 | 6480464 | nickel chloride results in increased phosphorylation of TP73 protein | CTD | PMID:21466819 |
| quercetin | increases expression | ISO | RGD:1316062 | 6480464 | Quercetin results in increased expression of TP73 protein | CTD | PMID:18331776 PMID:19397994 |
| quercetin | increases expression | ISO | RGD:1316062 | 6480464 | Quercetin results in increased expression of TP73 protein | CTD | PMID:19397994 PMID:18331776 |
| raloxifene | decreases expression | ISO | RGD:1316062 | 6480464 | Raloxifene results in decreased expression of TP73 mRNA | CTD | PMID:19429434 |
| resveratrol | increases expression | ISO | RGD:1316062 | 6480464 | resveratrol results in increased expression of TP73 mRNA; more ... | CTD | PMID:18347188 |
| sirolimus | multiple interactions | ISO | RGD:1316062 | 6480464 | [Sirolimus co-treated with Cisplatin] results in increased expression of TP73 protein; more ... | CTD | PMID:20686837 |
| sirolimus | increases expression | ISO | RGD:1316062 | 6480464 | Sirolimus results in increased expression of TP73 protein | CTD | PMID:21245298 |
| sirolimus | multiple interactions | ISO | RGD:1316062 | 6480464 | Sirolimus inhibits the reaction [TP73 protein affects the activity of HEN1 protein]; more ... | CTD | PMID:21245298 |
| trans-resveratrol | increases expression | ISO | RGD:1316062 | 6480464 | resveratrol results in increased expression of TP73 mRNA; more ... | CTD | PMID:18347188 |
| trimellitic anhydride | increases expression | ISO | RGD:1316063 | 6480464 | trimellitic anhydride results in increased expression of TRP73 mRNA | CTD | PMID:19042947 |
| wortmannin | multiple interactions | ISO | RGD:1316062 | 6480464 | wortmannin promotes the reaction [Doxorubicin results in increased expression of TP73 protein]; more ... | CTD | PMID:21214929 |
| zinc atom | multiple interactions | ISO | RGD:1316062 | 6480464 | Zinc binds to and affects the folding of and affects the activity of TP73 protein | CTD | PMID:17170001 |
| zinc atom | decreases expression | ISO | RGD:1316062 | 6480464 | Zinc deficiency results in decreased expression of TP73 mRNA | CTD | PMID:18356318 |
| zinc(0) | multiple interactions | ISO | RGD:1316062 | 6480464 | Zinc binds to and affects the folding of and affects the activity of TP73 protein | CTD | PMID:17170001 |
| zinc(0) | decreases expression | ISO | RGD:1316062 | 6480464 | Zinc deficiency results in decreased expression of TP73 mRNA | CTD | PMID:18356318 |