Gene: Kmt2a (lysine (K)-specific methyltransferase 2A) Rattus norvegicus
Symbol: Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone methyltransferase activity (H3-K4 specific) (ortholog); identical protein binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); DNA methylation (ortholog); embryonic hemopoiesis (ortholog); PARTICIPATES IN DNA modification pathway; histone modification pathway; ASSOCIATED WITH Growth Deficiency and Mental Retardation with Facial Dysmorphism (ortholog); Leukemia, Biphenotypic, Acute (ortholog); Leukemia, Myeloid, Acute (ortholog); FOUND IN cytoplasm (ortholog); histone methyltransferase complex (ortholog); MLL1 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; dibutyl phthalate
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase MLL; Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene); Mll; Mll1; Mll_mapped; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (mapped); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.0849,110,407 - 49,185,872-NCBI
Rat Cytogenetic Map8q22 NCBI
RGSC Genome Assembly v5.0847,728,915 - 47,804,551-NCBI
RGSC Genome Assembly v3.4847,759,175 - 47,834,586-NCBI
Rat Celera Assembly844,701,780 - 44,779,960-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kmt2a
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1586165
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2014-10-14
Status: ACTIVE