Gene: Kmt2a (lysine (K)-specific methyltransferase 2A) Rattus norvegicus
Symbol: Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Description: ENCODES a protein that exhibits chromatin binding (ortholog); core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN membrane depolarization; response to potassium ion; anterior/posterior pattern specification (ortholog); PARTICIPATES IN DNA modification pathway; histone modification pathway; ASSOCIATED WITH Abnormalities, Multiple (ortholog); De Lange Syndrome (ortholog); Growth Deficiency and Mental Retardation with Facial Dysmorphism (ortholog); FOUND IN cytoplasm (ortholog); histone methyltransferase complex (ortholog); MLL1 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; dibutyl phthalate
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase MLL; Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or trithorax Drosophila gene); Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene); Mll; Mll1; Mll_mapped; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (mapped); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.0849,110,407 - 49,185,872-NCBI
Rat Cytogenetic Map8q22 NCBI
RGSC Genome Assembly v5.0847,728,915 - 47,804,551-NCBI
RGSC Genome Assembly v3.4847,759,175 - 47,834,586-NCBI
Rat Celera Assembly844,701,780 - 44,779,960-NCBI

Launch Genome Browser (GBrowse)     Launch JBrowse

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Kmt2a
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1586165
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE