Gene: Kmt2a (lysine methyltransferase 2A) Rattus norvegicus
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Symbol: Kmt2a
Name: lysine methyltransferase 2A
Description: ENCODES a protein that exhibits chromatin binding (ortholog); core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN membrane depolarization; response to potassium ion; anterior/posterior pattern specification (ortholog); PARTICIPATES IN DNA modification pathway; histone modification pathway; ASSOCIATED WITH Abnormalities, Multiple (ortholog); acute lymphocytic leukemia (ortholog); acute monocytic leukemia (ortholog); FOUND IN cytosol (ortholog); histone methyltransferase complex (ortholog); MLL1 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; dibutyl phthalate
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; lysine (K)-specific methyltransferase 2A; Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or trithorax Drosophila gene); Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene); Mll; Mll1; Mll_mapped; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (mapped); myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1
Orthologs:
Homo sapiens (human) : KMT2A (lysine methyltransferase 2A)  HGNC
Mus musculus (house mouse) : Kmt2a (lysine (K)-specific methyltransferase 2A)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Kmt2a (lysine methyltransferase 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT2A (lysine methyltransferase 2A)
Canis lupus familiaris (dog) : KMT2A (lysine methyltransferase 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt2a (lysine methyltransferase 2A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0849,110,407 - 49,185,872 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0847,728,915 - 47,804,551 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4847,759,175 - 47,834,586 (-)NCBIRGSC3.4rn4RGSC3.4
Celera844,701,780 - 44,782,476 (-)NCBI
Cytogenetic Map8q22NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kmt2a
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RGD Object Information
RGD ID: 1586165
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE