Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1-chloro-2,4-dinitrobenzene | increases oxidation | ISO | RGD:733019 | 6480464 | Dinitrochlorobenzene results in increased oxidation of PRDX2 protein | CTD | PMID:18789312 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:735477 | 6480464 | Ethinyl Estradiol results in increased expression of PRDX2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:735477 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRDX2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | RGD:733019 | 6480464 | Estradiol results in decreased expression of PRDX2 mRNA | CTD | PMID:23019147 | 17beta-estradiol | decreases expression | ISO | RGD:733019 | 6480464 | Estradiol results in decreased expression of PRDX2 mRNA | CTD | PMID:23019147 PMID:23373633 | 1H-pyrazole | decreases expression | ISO | RGD:735477 | 6480464 | pyrazole results in decreased expression of PRDX2 mRNA | CTD | PMID:17945193 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:735477 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRDX2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:735477 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PRDX2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:735477 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRDX2 mRNA | CTD | PMID:19770486 | 2-butoxyethanol | increases expression | ISO | RGD:735477 | 6480464 | n-butoxyethanol results in increased expression of PRDX2 mRNA | CTD | PMID:19812364 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of PRDX2 mRNA | CTD | PMID:9681501 | 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:733019 | 6480464 | decitabine results in increased expression of PRDX2 mRNA | CTD | PMID:19194470 | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | all-trans-retinoic acid | decreases response to substance | ISO | RGD:733019 | 6480464 | PRDX2 protein results in decreased susceptibility to Tretinoin | CTD | PMID:16932348 | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PRDX2 mRNA | CTD | PMID:16483693 | arsenic atom | affects metabolic processing | ISO | RGD:733019 | 6480464 | PRDX2 protein affects the metabolism of Arsenic | CTD | PMID:18682255 | ATP | increases expression | EXP | | 6480464 | Adenosine Triphosphate results in increased expression of PRDX2 protein modified form | CTD | PMID:16178011 | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | decreases expression | ISO | RGD:733019 | 6480464 | Benzo(a)pyrene results in decreased expression of PRDX2 protein | CTD | PMID:17292933 | benzo[a]pyrene | decreases expression | ISO | RGD:735477 | 6480464 | Benzo(a)pyrene results in decreased expression of PRDX2 mRNA | CTD | PMID:19770486 PMID:22641617 | benzo[a]pyrene | increases expression | ISO | RGD:735477 | 6480464 | Benzo(a)pyrene results in increased expression of PRDX2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | RGD:735477 | 6480464 | Benzo(a)pyrene results in decreased expression of PRDX2 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | multiple interactions | ISO | RGD:733019 | 6480464 | Quercetin inhibits the reaction [Benzo(a)pyrene results in decreased expression of PRDX2 protein] | CTD | PMID:17292933 | benzo[a]pyrene | multiple interactions | ISO | RGD:735477 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in increased expression of PRDX2 mRNA | CTD | PMID:21715664 | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of PRDX2 protein | CTD | PMID:21699967 | cadmium dichloride | decreases expression | ISO | RGD:735477 | 6480464 | Cadmium Chloride results in decreased expression of PRDX2 mRNA | CTD | PMID:17499415 | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of PRDX2 protein | CTD | PMID:16470657 | cocaine | affects expression | ISO | RGD:733019 | 6480464 | Cocaine affects the expression of PRDX2 protein | CTD | PMID:19393250 | cocaine | decreases expression | ISO | RGD:733019 | 6480464 | Cocaine results in decreased expression of PRDX2 protein | CTD | PMID:17075605 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of PRDX2 mRNA | CTD | PMID:19497425 | copper atom | affects binding | ISO | RGD:733019 | 6480464 | PRDX2 protein binds to Copper | CTD | PMID:15359738 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of PRDX2 mRNA | CTD | PMID:19497425 | copper(0) | affects binding | ISO | RGD:733019 | 6480464 | PRDX2 protein binds to Copper | CTD | PMID:15359738 | copper(2+) sulfate | decreases expression | ISO | RGD:733019 | 6480464 | Copper Sulfate results in decreased expression of PRDX2 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | RGD:733019 | 6480464 | Cyclosporine results in decreased expression of PRDX2 mRNA | CTD | PMID:20106945 | cypermethrin | increases expression | ISO | RGD:735477 | 6480464 | cypermethrin results in increased expression of PRDX2 mRNA | CTD | PMID:21142847 | Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:735477 | 6480464 | Tetrahydrocannabinol results in increased expression of PRDX2 protein | CTD | PMID:18584336 | Delta(9)-tetrahydrocannabinol | decreases expression | ISO | RGD:733019 | 6480464 | Tetrahydrocannabinol results in decreased expression of PRDX2 mRNA | CTD | PMID:15454482 | deoxycholic acid | decreases response to substance | ISO | RGD:733019 | 6480464 | PRDX2 protein results in decreased susceptibility to Deoxycholic Acid | CTD | PMID:12507930 | diarsenic trioxide | decreases expression | ISO | RGD:735477 | 6480464 | arsenic trioxide results in decreased expression of PRDX2 mRNA | CTD | PMID:21173536 | dibutyl phthalate | decreases expression | ISO | RGD:735477 | 6480464 | Dibutyl Phthalate results in decreased expression of PRDX2 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | ISO | RGD:735477 | 6480464 | Dibutyl Phthalate results in decreased expression of PRDX2 mRNA | CTD | PMID:17361019 PMID:21266533 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of PRDX2 mRNA | CTD | PMID:18636392 | dimethylarsinic acid | increases expression | EXP | | 6480464 | Cacodylic Acid results in increased expression of PRDX2 mRNA | CTD | PMID:16122865 | dioxygen | multiple interactions | ISO | RGD:735477 | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of PRDX2 mRNA] | CTD | PMID:22629407 | dioxygen | increases expression | ISO | RGD:735477 | 6480464 | Oxygen deficiency results in increased expression of PRDX2 mRNA | CTD | PMID:22629407 | doxorubicin | multiple interactions | ISO | RGD:735477 | 6480464 | MT2 affects the reaction [Doxorubicin results in increased expression of PRDX2 mRNA]; more ... | CTD | PMID:21463615 | doxorubicin | increases expression | ISO | RGD:735477 | 6480464 | Doxorubicin results in increased expression of PRDX2 mRNA; more ... | CTD | PMID:21463615 | elemental selenium | decreases expression | EXP | | 6480464 | Selenium deficiency results in decreased expression of PRDX2 mRNA | CTD | PMID:15792362 | formaldehyde | decreases expression | ISO | RGD:733019 | 6480464 | Formaldehyde results in decreased expression of PRDX2 mRNA; more ... | CTD | PMID:20347000 | formaldehyde | multiple interactions | ISO | RGD:733019 | 6480464 | PRDX2 protein inhibits the reaction [Formaldehyde results in increased activity of CASP3 protein]; more ... | CTD | PMID:20347000 | graphite | decreases expression | ISO | RGD:733019 | 6480464 | Graphite results in decreased expression of PRDX2 protein | CTD | PMID:22157353 | hexachlorobenzene | increases expression | EXP | | 6480464 | Hexachlorobenzene results in increased expression of PRDX2 mRNA | CTD | PMID:15159207 | hyaluronic acid | decreases expression | EXP | | 6480464 | Hyaluronic Acid analog results in decreased expression of PRDX2 protein | CTD | PMID:23178681 | hydrogen peroxide | increases expression | ISO | RGD:733019 | 6480464 | Hydrogen Peroxide results in increased expression of PRDX2 protein | CTD | PMID:11295360 | hydrogen peroxide | decreases expression | EXP | | 6480464 | Hydrogen Peroxide results in decreased expression of PRDX2 protein | CTD | PMID:23178681 | hydrogen peroxide | increases expression | EXP | | 6480464 | Hydrogen Peroxide results in increased expression of PRDX2 protein modified form | CTD | PMID:16178011 | hydrogen peroxide | decreases expression | ISO | RGD:735477 | 6480464 | Hydrogen Peroxide results in decreased expression of PRDX2 mRNA | CTD | PMID:14729362 | hydrogen peroxide | decreases response to substance | ISO | RGD:733019 | 6480464 | PRDX2 protein results in decreased susceptibility to Hydrogen Peroxide | CTD | PMID:11469800 | ibuprofen | affects expression | ISO | RGD:733019 | 6480464 | Ibuprofen affects the expression of PRDX2 protein | CTD | PMID:18351690 | ibuprofen | increases expression | ISO | RGD:733019 | 6480464 | Ibuprofen results in increased expression of PRDX2 mRNA | CTD | PMID:18351690 | isotretinoin | decreases expression | ISO | RGD:733019 | 6480464 | Isotretinoin results in decreased expression of PRDX2 mRNA | CTD | PMID:20436886 | kojic acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX2 mRNA | CTD | PMID:18544905 | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | lead(0) | decreases expression | ISO | RGD:733019 | 6480464 | Lead results in decreased expression of PRDX2 mRNA | CTD | PMID:19921347 | mercury atom | increases expression | EXP | | 6480464 | Mercury results in increased expression of PRDX2 mRNA | CTD | PMID:12730625 | mercury(0) | increases expression | EXP | | 6480464 | Mercury results in increased expression of PRDX2 mRNA | CTD | PMID:12730625 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of PRDX2 protein | CTD | PMID:19826936 | methamphetamine | decreases expression | ISO | RGD:735477 | 6480464 | Methamphetamine results in decreased expression of PRDX2 protein | CTD | PMID:16181420 | mitoxantrone | affects response to substance | ISO | RGD:733019 | 6480464 | PRDX2 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | mono(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of PRDX2 mRNA | CTD | PMID:22087261 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX2 mRNA | CTD | PMID:18544905 | naphthalene | affects binding | ISO | RGD:735477 | 6480464 | naphthalene metabolite binds to PRDX2 protein | CTD | PMID:15892573 | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of PRDX2 mRNA | CTD | PMID:18636392 | paclitaxel | affects response to substance | ISO | RGD:733019 | 6480464 | PRDX2 protein affects the susceptibility to Paclitaxel | CTD | PMID:16217747 | paracetamol | decreases expression | ISO | RGD:735477 | 6480464 | Acetaminophen results in decreased expression of PRDX2 mRNA | CTD | PMID:17585979 | paracetamol | affects expression | ISO | RGD:735477 | 6480464 | Acetaminophen affects the expression of PRDX2 mRNA | CTD | PMID:17562736 | paraquat | increases expression | ISO | RGD:733019 | 6480464 | Paraquat results in increased expression of PRDX2 protein modified form | CTD | PMID:11697128 | paraquat | decreases expression | ISO | RGD:735477 | 6480464 | Paraquat results in decreased expression of PRDX2 mRNA | CTD | PMID:21371552 | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | quercetin | multiple interactions | ISO | RGD:733019 | 6480464 | Quercetin inhibits the reaction [Benzo(a)pyrene results in decreased expression of PRDX2 protein] | CTD | PMID:17292933 | quercetin | increases expression | ISO | RGD:733019 | 6480464 | Quercetin results in increased expression of PRDX2 protein | CTD | PMID:17292933 | raloxifene | affects expression | EXP | | 6480464 | Raloxifene affects the expression of PRDX2 mRNA | CTD | PMID:16079270 | rosiglitazone | affects expression | ISO | RGD:733019 | 6480464 | rosiglitazone affects the expression of PRDX2 protein | CTD | PMID:19556978 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of PRDX2 mRNA | CTD | PMID:19013527 | selenium atom | decreases expression | EXP | | 6480464 | Selenium deficiency results in decreased expression of PRDX2 mRNA | CTD | PMID:15792362 | streptozocin | decreases expression | ISO | RGD:735477 | 6480464 | Streptozocin results in decreased expression of PRDX2 mRNA | CTD | PMID:20446767 | streptozocin | multiple interactions | ISO | RGD:733019 | 6480464 | PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA] | CTD | PMID:20446767 | tert-butyl hydroperoxide | decreases expression | ISO | RGD:733019 | 6480464 | tert-Butylhydroperoxide results in decreased expression of PRDX2 mRNA | CTD | PMID:15336504 | tert-butyl hydroperoxide | decreases expression | ISO | RGD:735477 | 6480464 | tert-Butylhydroperoxide results in decreased expression of PRDX2 mRNA | CTD | PMID:14729362 | tert-butyl hydroperoxide | increases expression | ISO | RGD:733019 | 6480464 | tert-Butylhydroperoxide results in increased expression of PRDX2 protein | CTD | PMID:11295360 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PRDX2 protein | CTD | PMID:16845489 | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of PRDX2 mRNA | CTD | PMID:19483382 | troglitazone | decreases expression | ISO | RGD:733019 | 6480464 | troglitazone results in decreased expression of PRDX2 mRNA | CTD | PMID:19140230 | uranium atom | affects expression | ISO | RGD:733019 | 6480464 | Uranium affects the expression of PRDX2 mRNA | CTD | PMID:15672453 | zinc atom | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of PRDX2 mRNA | CTD | PMID:11717422 | zinc(0) | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of PRDX2 mRNA | CTD | PMID:11717422 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process









