Gene: Kras (Kirsten rat sarcoma viral oncogene) Rattus norvegicus
Symbol: Kras
Name: Kirsten rat sarcoma viral oncogene
Description: ENCODES a protein that exhibits GDP binding; GMP binding; LRR domain binding; INVOLVED IN cytokine-mediated signaling pathway; positive regulation of MAP kinase activity; positive regulation of NF-kappaB transcription factor activity; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; endometrial cancer pathway; ASSOCIATED WITH Endometrial Neoplasms; Kidney Failure, Chronic; Sarcoma, Experimental; FOUND IN membrane raft; mitochondrion; cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2-trans,6-trans-farnesyl diphosphate; 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine
Type: protein-coding
Also known as: c-K-ras; c-K-ras2 protein; c-Ki-ras; c-Kirsten-ras proto-oncogene; GTPase KRas; K-Ras 2; ki-Ras; Kirsten rat sarcoma viral oncogene homologue 2 (active); Kras2; p21; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.04179,483,086 - 179,515,609-NCBI
Rat Cytogenetic Map4q44 NCBI
RGSC Genome Assembly v5.04243,667,912 - 243,696,325-NCBI
RGSC Genome Assembly v3.44182,869,242 - 182,895,106-NCBI
Rat Celera Assembly4166,708,846 - 166,734,692-NCBI
Genome Assembly 3.14183,114,365 - 183,140,230-NCBI

Launch Genome Browser (GBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kras
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2981
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE